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Evaluation of ovulation and corpus luteum function using measurements of plasma progesterone

Abraham GE et al., 1974 Obstetrics and Gynecology

To develop a practical yet statistically valid means of indicating ovulation and adequacy of corpus luteum function concentrations of plasma progesterone (P) were measured daily during the luteal phas...

Reproductive Endocrinology > Corpus Luteum > Luteal Phase AssessmentDiagnostics > Hormone Assays > Progesterone MeasurementInfertility > Diagnostics > Ovulation Confirmation

Ovulatory failure in a normal population and in patients with breast cancer

Swain MC et al., 1974 The Journal of Obstetrics and Gynaecology of the British Commonwealth

The luteal phase plasma progesterone levels of 341 control patients were compared with those in 25 patients with early and 12 patients with advanced breast cancer. There was a significant increase of ...

Reproductive Endocrinology > Ovulatory Dysfunction > AnovulationGeneral OB/GYN > Breast Health > Breast Cancer Hormonal AssociationsMenstrual Cycle > Luteal Phase > Luteal Phase Deficiency

Low-dosage clomiphene therapy in the treatment of infertility due to defective ovulation

Barrett CT et al., 1974 South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde

Summary: The use of clomiphene in gradually increasing doses, in cases of infertility due to anovulation, oligo-ovulation and inadequate luteal phase, led to a high pregnancy rate, particularly in the...

Infertility > Medical Treatment > Clomiphene CitrateInfertility > Ovulation Induction > Dose OptimizationReproductive Endocrinology > Ovulatory Dysfunction > Anovulation Treatment

Measurement of serum LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the inadequate luteal phase

Sherman BM et al., 1974 The Journal of Clinical Endocrinology and Metabolism

The irregular menses experienced by obese and/or hirsute women were studied by daily measurement of serum LH, FSH, estradiol (E2) and progesterone (P). During 8 cycles of 24 to 157 days, each episode ...

Reproductive Endocrinology > Corpus Luteum > Luteal Phase DeficiencyMenstrual Cycle > Disorders > Oligomenorrhea Hormonal ProfileInfertility > Diagnostics > Hormonal Evaluation of Ovulatory Dysfunction

Estrogen and progesterone in plasma in relation to premenstrual tension

Carstensen H et al., 1974 Journal of Steroid Biochemistry

Plasma concentration of estrogen and progesterone were measured during the last 6 days of the menstrual cycle in women with premenstrual tension, and compared with a group of healthy women. Those wome...

Reproductive Endocrinology > Steroid Hormones > Estrogen-Progesterone BalanceMenstrual Cycle > Premenstrual Disorders > Hormonal EtiologyGeneral OB/GYN > Premenstrual Syndrome > Hormone Profiles

Effect of progesterone and 17-hydroxyprogesterone caproate on normal corpus luteum function

Aksel S et al., 1974 American Journal of Obstetrics and Gynecology

A group of infertility patients were evaluated by an endometrial biopsy, timed with a basal body temperature chart, serum luteinizing hormone radioimmunassay to pinpoint ovulation, and daily serum pro...

Reproductive Endocrinology > Corpus Luteum > Exogenous Progesterone EffectsInfertility > Medical Treatment > Luteal Phase Progesterone SupportDiagnostics > Endometrial Biopsy > Luteal Phase Dating

Plasma progesterone levels in normal and abnormal pregnancies

Lindberg BS et al., 1974 Acta Obstetricia Et Gynecologica Scandinavica

Plasma progesterone levels were estimated by competitive protein binding in 815 samples from healthy pregnant women with uncomplicated pregnancies. This series includes 32 patients who were followed s...

Reproductive Endocrinology > Progesterone > Plasma Levels in PregnancyPregnancy > High-Risk Pregnancy > Progesterone MonitoringDiagnostics > Hormone Assays > Progesterone Measurement

Recollections of my life with progesterone

Allen WM, 1974 Gynecologic Investigation

This paper gives in narrative style those phases of the corpus luteum story in which the author was an active participant. The first part deals with the exciting days at the University of Rochester wh...

Reproductive Endocrinology > Progesterone > History of DiscoveryEthics/Philosophy > History of Reproductive Medicine > Hormone Research

The ovulation method of family planning

France JT, 1973 IPPF Medical Bulletin

The ovulation method of family planning relies on self-recognition of physiological changes occuring around time of ovulation rather than a calendar to enable a couple to avoid sexual intercourse duri...

Fertility Awareness > Cervical Mucus Monitoring > Billings Ovulation MethodFertility Awareness > Method Effectiveness > Field TrialsBody Literacy > Fertility Signs > Mucus and Temperature Indicators

Oestriol and prevention of breast cancer

Lemon HM, 1973 Lancet (London, England)

Findings of estriol protective action against chemical carcinogens used to induce breast cancer in laboratory animals.

Reproductive Endocrinology > Estrogens > Estriol and Cancer ProtectionGeneral OB/GYN > Breast Health > Hormonal Cancer Prevention

The influence of fetal sex on the levels of plasma progesterone in the human fetus

Hagemenas FC et al., 1973 The Journal of Clinical Endocrinology and Metabolism

Progesterone levels in the human fetoplacental unit at term were determined by a competitive protein binding method. Progesterone levels in the umbilical vein were always higher than in the umbilical ...

Reproductive Endocrinology > Progesterone > Fetal Progesterone MetabolismPregnancy > Fetoplacental Unit > Sex-Related Hormonal Differences

The prevention of postoperative pelvic adhesions following conservative operative treatment for human infertility. A final 3-year follow-up report

Horne HW Jr et al., 1973 International Journal of Fertility

A combination of Decadreon (dexamethasone) and Phenergan (promethazine) was tested in this collaborative study of 240 infertility patients as a means of preventing postoperative adhesion formation aft...

Surgery > Adhesion Prevention > Corticosteroid ProtocolsInfertility > Surgical Treatment > Postoperative OutcomesSurgery > Pelvic Surgery > Reproductive Surgery Outcomes

Ovulation method of family planning

Billings JJ, 1972 Lancet (London, England)
Fertility Awareness > Cervical Mucus Monitoring > Billings Ovulation MethodBody Literacy > Fertility Signs > Cervical Mucus Patterns

A trial of the ovulation method of family planning in Tonga

Weissmann MC et al., 1972 Lancet (London, England)
Fertility Awareness > Billings Ovulation Method > Clinical TrialsFertility Awareness > Natural Family Planning > Effectiveness StudiesFertility Awareness > Billings Ovulation Method > International Applications

A composite picture of the menstrual cycle

Moghissi KS et al., 1972 American Journal of Obstetrics and Gynecology

Ten ovulating women were studied to assess the interrelationships of various systemic, hormonal, and reproductive tract changes during normal menstrual cycles. Samples of blood, 24 hour urine specimen...

Menstrual Cycle > Hormonal Profiles > Normal Cycle CharacterizationReproductive Endocrinology > Ovulation > Hormonal MarkersDiagnostics > Ovulation Detection > Multiparameter Assessment

The hypothalamus and reproduction

Schally AV et al., 1972 American Journal of Obstetrics and Gynecology

This article has been designed to review recent developments in the field of hypothalamic hormones involved in the control of reproductive functions. A brief resume of early physiologic and anatomic s...

Reproductive Endocrinology > Hypothalamic-Pituitary Axis > GnRH DiscoveryReproductive Endocrinology > Gonadotropins > FSH and LH RegulationInfertility > Ovulation Induction > GnRH Therapy

Stein-Leventhal syndrome

Halbe HW et al., 1972 American Journal of Obstetrics and Gynecology
PCOS > Diagnosis > Historical ClassificationPCOS > Pathophysiology > Stein-Leventhal SyndromeGeneral OB/GYN > Endocrine Disorders > Polycystic Ovary Syndrome

Endocrine profiles in premenstrual tension

Adamopoulos DA et al., 1972 Clinical Endocrinology

Summary: Studies on pituitary and ovarian function as assessed by the urinary output of total gonadotrophic activity, the three classical oestrogens, pregnanediol and, in some cases, testosterone and ...

Menstrual Cycle > Premenstrual Disorders > Hormonal ProfilesReproductive Endocrinology > Ovarian Function > Anovulation and PMSMenstrual Cycle > Luteal Phase > Premenstrual Syndrome Etiology

Outcome of pregnancy after induced ovulation. Follow-up of pregnancies and children born after clomiphene therapy

Hack M et al., 1972 JAMA

Eighty-six women reached at least 20 weeks' pregnancy in 96 instances, after ovulation induced by clomiphene citrate. Although 37 of the women had 44 previous pregnancies, there had been a high pregna...

Infertility > Ovulation Induction > Clomiphene Citrate OutcomesPregnancy > Complications > After Fertility TreatmentInfertility > Treatment Outcomes > Neonatal Follow-up

Plasma estrone, estradiol, estriol, progesterone, and 17-hydroxyprogesterone in human pregnancy. I. Normal pregnancy

Tulchinsky D et al., 1972 American Journal of Obstetrics and Gynecology

To describe normal relationships between the various plasma unconjugated estrogens and progesterone during the second half of human pregnancy, the plasma concentrations of progesterone, 17-hydroxyprog...

Reproductive Endocrinology > Steroid Hormones > Pregnancy Hormone ProfilesPregnancy > Normal Physiology > Hormonal ChangesDiagnostics > Hormone Measurement > Pregnancy Reference Values

Single luteal phase serum progesterone assay as an indicator of ovulation

Israel R et al., 1972 American Journal of Obstetrics and Gynecology

A study was undertaken to determine whether solitary progesterone as says performed on serum samples obtained in the midluteal phase would provide the clinician with a convenient indicator that ovulat...

Reproductive Endocrinology > Progesterone > Luteal Phase AssessmentDiagnostics > Ovulation Confirmation > Serum ProgesteroneInfertility > Diagnostic Evaluation > Hormonal Testing

The significance of the human corpus luteum in pregnancy maintenance. I. Preliminary studies

Csapo AI et al., 1972 American Journal of Obstetrics and Gynecology

Following the total removal of luteal tissue, circulating plasma progesterone, intrauterine pressure, oxytocin response, and clinical progress in abortion were determined sequentially in 12 first-trim...

Pregnancy > Early Pregnancy > Corpus Luteum FunctionReproductive Endocrinology > Progesterone > Luteoplacental ShiftPregnancy > Miscarriage > Progesterone Deficiency Mechanisms

Symptoms and hormonal changes accompanying ovulation

Billings EL et al., 1972 Lancet (London, England)
Fertility Awareness > Billings Ovulation Method > Hormonal CorrelationMenstrual Cycle > Ovulation > Symptoms and SignsBody Literacy > Cervical Mucus > Ovulation Detection

Luteal Phase Defects: Diagnosis and Implications

Hilgers TW, 1972 xPharm: The Comprehensive Pharmacology Reference
Reproductive Endocrinology > Luteal Phase Deficiency > DiagnosisNaProTECHNOLOGY > Hormonal Assessment > Luteal Phase EvaluationInfertility > Hormonal Causes > Progesterone Insufficiency

Prostaglandin-induced myometrial activity inhibited by progesterone

Porter DG et al., 1971 Nature

PROSTAGLANDINS (PGs) are being used increasingly as abortifacients although their precise mechanism of action is uncertain. One of the compounds frequently used is PGF2α, which has been shown to stimu...

Reproductive Endocrinology > Progesterone > Myometrial EffectsReproductive Endocrinology > Prostaglandins > Uterine ActivityPregnancy > Uterine Physiology > Progesterone-Prostaglandin Interaction

Use-effectiveness of oral and intrauterine contraception

Lewitt S et al., 1971 Fertility and Sterility

The use-effectiveness of oral contraception and intrauterine contraception was studied in 3 family planning centers in the United States: Grady Memorial Hospital in Atlanta, Georgia; State University ...

Contraception/Comparison > IUD vs Oral Contraceptives > Use EffectivenessContraception/Comparison > Continuation Rates > Method ComparisonContraception/Comparison > Failure Rates > Clinical Outcomes

Psychology of the misuse and rejection of contraception

Sandberg EC et al., 1971 American Journal of Obstetrics and Gynecology

Some of the psychological influences on contraceptive misuse and rejection are presented, ranging from denial (of the possibility of pregnancy), guilt, sexual identity conflicts, to fear, opportunism ...

Contraception/Comparison > Adherence and Compliance > Psychological FactorsEthics/Philosophy > Contraception > Psychological and Social DimensionsContraception/Comparison > User Experience > Barriers to Compliance

The IUD and the pill: extended use-effectiveness

Lewit S et al., 1971 Family Planning Perspectives

The extended use-effectiveness of IUD and oral pills as measured by 1) their theoretical effectiveness 2) consistency of use and 3) continuation of use in preventing unwanted pregnancies was studied f...

Contraception/Comparison > IUD vs Oral Contraceptives > Extended EffectivenessContraception/Comparison > Continuation Rates > Long-term OutcomesContraception/Comparison > Unplanned Pregnancy > Method-Specific Risk

Experience with induction of ovulation

MacLeod SC et al., 1970 American Journal of Obstetrics and Gynecology

One hundred and thirty-five patients diagnosed as ovulatory failure have been treated in our clinic since 1966. One hundred and eighteen of these have been treated with clomiphene citrate, or more rec...

Infertility > Ovulation Induction > Clomiphene CitrateInfertility > Ovulation Induction > Gonadotropin TherapyReproductive Endocrinology > Anovulation > Medical Treatment

Plasma progesterone secretion by the corpus luteum of term pregnancy

LeMaire WJ et al., 1970 American Journal of Obstetrics and Gynecology

Plasma progesterone concentration was determined in the maternal peripheral vein, umbilical vein, uterine vein, and both ovarian veins at elective cesarean section in term pregnancy. In 10 cases plasm...

Reproductive Endocrinology > Progesterone > Corpus Luteum FunctionPregnancy > Physiology > Ovarian Hormone Production

The short luteal phase

Strott CA et al., 1970 The Journal of Clinical Endocrinology and Metabolism

From among a group of women with apparently normal menstrual cycles, 7 cycles with short luteal phases were identified. These cycles were characterized by grossly normal FSH and LH patterns although t...

Reproductive Endocrinology > Luteal Phase > Luteal Phase DeficiencyMenstrual Cycle > Hormonal Patterns > Progesterone DynamicsInfertility > Luteal Phase Defect > Endocrine Characterization

Plasma levels of progesterone in pregnancy measured by a rapid competitive protein binding technique

Johansson ED, 1969 Acta Endocrinologica

Plasma levels of progesterone* were measured during normal human pregnancy by a sensitive and rapid competitive protein binding technique. During the first half of gestation 440 determinations in 321 ...

Pregnancy > Hormonal Monitoring > Progesterone LevelsReproductive Endocrinology > Progesterone > Gestational ProfilesDiagnostics > Hormone Assays > Competitive Protein Binding

Evaluation of a new ovulatory stimulating agent: clomiphene citrate (clomid)

No Authors Listed, 1968 JAMA

Clomiphene citrate, in selected patients, is an effective agent for the treatment of infertility due to anovulation. An adequate laboratory and physical evaluation of each individual patient is essent...

Infertility > Ovulation Induction > Clomiphene CitrateReproductive Endocrinology > Pharmacology > Ovulatory AgentsGeneral OB/GYN > Drug Evaluation > Adverse Effects

Plasma progesterone levels in normal pregnancy, labor, and the puerperium. I. Method of assay

Yannone ME, 1968 American Journal of Obstetrics and Gynecology

A method to measure plasma progesterone by gas-liquid chromatography is presented. The procedure allows for the preparation of a plasma progesterone extract clean enough for accurate submicrogram quan...

Diagnostics > Hormone Assays > Progesterone MeasurementPregnancy > Endocrinology > Progesterone LevelsResearch Methodology > Laboratory Techniques > Chromatography