Successful ongoing natural pregnancies and healthy live births in women with low and very low antimullerian hormone levels in a private practice setting in Lima-Peru. A case series report

Valer Chavez G, Sandoval I

Published August 9, 2024 IIRRM 2024 Congress, Vancouver

Abstract

In Peru, IVF centers usually advise women to consider ovodonation when they have low antimullerian hormone (AMH) values. We know that other than age, few factors can predict the chances of natural fertility and the AMH predictive value for clinical pregnancy remains controversial. We present a case series report of 10 patients, from February 2022 to April 2024. These women have ongoing natural pregnancies and healthy live births, although their AMH values were low(<1ng/ml) and very low (<0,4 ng/ml). This is the first report of its kind in our country. In these case series decreased AMH level does not represent decreased natural fertility in young or old females. We consider that any preconceptional counseling or infertility treatment options should not be based in the misconception about the low and very low AMH values as predictors of failure to have a natural pregnancy and healthy live birth, to avoid creating anxiety to couples and, more important, referring women to ovodonation Our cases could support the findings of several studies affirming that a decreased AMH level does not represent decreased fertility in young or old females. Evidence shows that serum AMH levels are not associated with fecundability women of childbearing age. Therefore, they should not be used as a fertility test or to deny access to infertility treatment. Likewise, the available evidence does not consistently suggest an increased risk of pregnancy loss or fetal abnormalities in naturally conceived pregnancies of women with lower ovarian reserve.

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