Anovulatory Cycles
Anovulatory cycles are menstrual cycles in which the ovaries do not release an egg, though bleeding may still occur and be mistaken for a normal period. Anovulation is one of the most common causes of female infertility, accounting for roughly 30% of cases. The absence of ovulation means the corpus luteum never forms, progesterone is not produced, and the luteal phase does not occur.1
Common causes include polycystic ovary syndrome (PCOS), hyperprolactinemia, hypothyroidism, hypothalamic dysfunction (from excessive exercise or very low body weight), and perimenopause. Each cause has distinct hormonal fingerprints, and distinguishing them matters. Treating PCOS-driven anovulation is not the same as treating prolactin-driven anovulation. The cause determines the protocol.
In RRM, anovulation is identified through cycle charting (absence of a post-peak phase on the CrMS chart), serial follicular ultrasound, and targeted hormonal panels timed to the cycle. Charting data reveals the pattern cycle by cycle. Without it, clinicians are working without the most basic diagnostic information. Ovulation is a sign of health.2 When it is absent, RRM clinicians investigate the reason rather than bypass the system.
Cited in this entry
- Successful Implementation of Menstrual Cycle Biomarkers in the Treatment of Infertility in Polycystic Ovary Syndrome. https://pubmed.ncbi.nlm.nih.gov/36833150/
- Ovulation, a sign of health. https://pubmed.ncbi.nlm.nih.gov/29255329/
This content is for educational purposes only and does not constitute medical advice. Consult an RRM clinician or healthcare provider for guidance specific to your situation.