HCG Trigger (Human Chorionic Gonadotropin Trigger)
A single injection of human chorionic gonadotropin (hCG) given during an ovulation induction or monitored cycle to mimic the natural LH surge, triggering final follicular maturation and ovulation. In NaPro Medical and related RRM protocols, hCG triggering is used selectively when cycle-timed monitoring identifies a mature follicle with a delayed or absent endogenous LH surge, or to improve the precision of ovulation timing in combination with ovulation induction agents such as clomiphene or letrozole. Post-ovulatory hCG "boosters" also support corpus luteum function and early luteal progesterone production. Unlike IVF protocols, which use hCG triggering to time oocyte retrieval, RRM protocols use it to support natural intercourse-timed conception within the body.
This content is for educational purposes only and does not constitute medical advice. Consult an RRM clinician or healthcare provider for guidance specific to your situation.