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Perfluorochemicals and endometriosis: the ENDO study

Louis GMB et al., 2012 Epidemiology (Cambridge, Mass.)

Background: Environmental chemicals may be associated with endometriosis. No published research has focused on the possible role of perfluorochemicals (PFCs) despite their widespread presence in human...

EndometriosisReproductive Endocrinology

Recent combined hormonal contraceptives (CHCs) and the risk of thromboembolism and other cardiovascular events in new users

Sidney S et al., 2013 Contraception

Background: Combined hormonal contraceptives (CHCs) place women at increased risk of venous thromboembolic events (VTEs) and arterial thrombotic events (ATEs), including acute myocardial infarction an...

Contraception/Comparison > Hormonal Contraceptives > Thromboembolism RiskContraception/Comparison > Safety > Cardiovascular EventsContraception/Comparison > Hormonal Contraceptives > Drospirenone

Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women

Daniel L Koller et al., 2012 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research

Previous genome-wide association studies (GWAS) have identified common variants in genes associated with variation in bone mineral density (BMD), although most have been carried out in combined sample...

Bone HealthReproductive Endocrinology

Marital fertility and income: moderating effects of the Church of Jesus Christ of Latter-day Saints religion in Utah

Smith KR et al., 2012 Journal of Biosocial Science

Utah has the highest total fertility of any state in the United States and also the highest proportion of population affiliated with the Church of Jesus Christ of Latter-day Saints (the LDS or Mormon ...

General OB/GYN > Reproductive Demographics > Religion and FertilityGeneral OB/GYN > Epidemiology > Sociodemographic DeterminantsEthics/Philosophy > Reproductive Ethics > Pronatalism

Oral contraceptive use and risk of breast cancer: a meta-analysis of prospective cohort studies

Zhu H et al., 2012 The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception

BACKGROUND AND Objectives: It has been suggested that taking oral contraceptives (OCs) may increase breast cancer incidence. However, data in this regard are inconsistent. We performed this meta-analy...

Contraception/Comparison > Oral Contraceptives > Breast Cancer RiskGeneral OB/GYN > Breast Health > Hormonal Risk FactorsResearch Methodology > Meta-Analysis > Prospective Cohort Studies

Fertility awareness-based methods of family planning: A review of effectiveness for avoiding pregnancy using SORT

Manhart MD et al., 2013 Osteopathic Family Physician

Each year, over three-fourths of the women of reproductive age in the United States seek family planning services from primary care clinicians. Women and their doctors should be informed of all effect...

Fertility Awareness > Effectiveness > Evidence ReviewFertility Awareness > Education > Clinician TrainingFertility Awareness > Methods Overview > Comparative Effectiveness

Vitamin D in the aetiology and management of polycystic ovary syndrome

Thomson RL et al., 2012 Clinical endocrinology

Vitamin D deficiency is common in women with polycystic ovary syndrome (PCOS), with the 67-85% of women with PCOS having serum concentrations of 25-hydroxy vitamin D (25OHD) <20 ng/ml. Vitamin D defic...

PCOS > Pathophysiology > Vitamin D DeficiencyPCOS > Treatment > Nutritional SupplementationPCOS > Comorbidities > Insulin Resistance

Luteal phase deficiency in normal cycling women

Hammoud A et al., 2012 Fertility and Sterility
Menstrual Cycle > Luteal Phase > Luteal Phase DeficiencyReproductive Endocrinology > Progesterone > Luteal InsufficiencyInfertility > Diagnosis > Luteal Phase Evaluation

Assisted reproductive techniques and NaProTechnology

Dowbór-Dzwonka A et al., 2012 Open Access Zdrowie publiczne

Infertility is a significant and constantly increasing individual and social problem. It is estimated that at present it affects approx. 15 to 20 percent of couples. Inability to conceive a child elic...

NaProTECHNOLOGY > Comparison > ART vs NaProTECHNOLOGYEthics/Philosophy > Reproductive Ethics > Assisted ReproductionInfertility > Treatment > Natural Procreation Methods

Inflammation, leukocytes and menstruation

Evans J et al., 2012 Reviews in Endocrine & Metabolic Disorders

Menstruation has many of the features of an inflammatory process. The complexity and sequence of inflammatory-type events leading to the final tissue breakdown and bleeding are slowly being unravelled...

Menstrual Cycle > Physiology > Endometrial InflammationReproductive Endocrinology > Progesterone > Endometrial EffectsMenstrual Cycle > Physiology > Tissue Breakdown and Repair

Progesterone for hot flush and night sweat treatment--effectiveness for severe vasomotor symptoms and lack of withdrawal rebound

Prior JC et al., 2012 Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology

A controlled trial recently showed that oral micronized progesterone (Progesterone, 300 mg at h.s. daily) was effective for vasomotor symptoms (VMS) in 133 healthy early postmenopausal women. Here, we...

Perimenopause/Menopause > Treatment > Progesterone TherapyPerimenopause/Menopause > Symptoms > Vasomotor SymptomsReproductive Endocrinology > Progesterone > Therapeutic Applications

Evaluation and treatment of recurrent pregnancy loss: a committee opinion

Reproductive Endocrinology Precis, 2012 Fertility and sterility

The majority of miscarriages are sporadic and most result from genetic causes that are greatly influenced by maternal age. Recurrent pregnancy loss (RPL) is defined by two or more failed clinical preg...

Infertility > Recurrent Pregnancy Loss > Evaluation GuidelinesPregnancy > Complications > Recurrent MiscarriageDiagnostics > Reproductive > Recurrent Pregnancy Loss Workup

Hot flushes and night sweats differ in associations with cardiovascular markers in healthy early postmenopausal women

Hitchcock CL et al., 2012 Menopause (New York, N.Y.)

Objective: The aim of this study was to evaluate the associations between vasomotor symptoms ([VMS] hot flushes or flashes and night sweats) and markers of cardiovascular risk. Methods: Healthy postm...

Perimenopause/Menopause > Symptoms > Vasomotor SymptomsPerimenopause/Menopause > Comorbidities > Cardiovascular RiskResearch Methodology > Clinical Trials > Randomized Controlled Trial

The relationship between proton pump inhibitor use and longitudinal change in bone mineral density: a population-based study [corrected] from the Canadian Multicentre Osteoporosis Study (CaMos)

Targownik LE et al., 2012 The American Journal of Gastroenterology

Objectives: Proton pump inhibitor (PPI) use has been identified as a risk factor for hip and vertebral fractures. Evidence supporting a relationship between PPI use and osteoporosis remains scant. Dem...

Bone HealthReproductive Endocrinology

Low-level laser in the treatment of patients with hypothyroidism induced by chronic autoimmune thyroiditis: a randomized, placebo-controlled clinical trial

Höfling DB et al., 2012 Lasers in Medical Science

Chronic autoimmune thyroiditis (CAT) is the most common cause of acquired hypothyroidism, which requires lifelong levothyroxine replacement therapy. Currently, no effective therapy is available for CA...

Diagnostics > Thyroid > Autoimmune Thyroiditis TreatmentResearch Methodology > Clinical Trials > Randomized Placebo-Controlled TrialReproductive Endocrinology > Thyroid Disorders > Hypothyroidism Management

Thrombotic stroke and myocardial infarction with hormonal contraception

Lidegaard Ø et al., 2012 The New England Journal of Medicine

Background: Although several studies have assessed the risk of venous thromboembolism with newer hormonal contraception, few have examined thrombotic stroke and myocardial infarction, and results have...

Contraception/Comparison > Adverse Effects > Cardiovascular RiskContraception/Comparison > Hormonal Contraception > Arterial ThrombosisResearch Methodology > Epidemiology > Historical Cohort Study

Rising incidence of multiple sclerosis in females associated with urbanization

Kotzamani D et al., 2012 Neurology

Objective: To design and perform a case-control study of multiple sclerosis (MS) in Crete, an island of 0.6 million people, that has experienced profound socioeconomic changes in recent decades. Meth...

General OB/GYN > Epidemiology > Autoimmune DiseaseContraception/Comparison > Side Effects > Neurological OutcomesGeneral OB/GYN > Environmental Health > Urbanization Effects

Adhesion prevention in endometriosis: a neglected critical challenge

Somigliana E et al., 2012 Journal of Minimally Invasive Gynecology

Prevention of adhesions, whether de novo or by re-formation, is one of the most important and surprisingly neglected aspect of the treatment of endometriosis. Adhesions may cause infertility, dyspareu...

Surgery > Adhesion Prevention > Anti-Adhesion AgentsEndometriosis > Surgical Treatment > Postoperative ComplicationsSurgery > Laparoscopy > Adhesion Management

Infertility treatment in a population-based sample: 2004-2005

Simonsen SE et al., 2012 Maternal and child health journal

To describe the characteristics of women seeking infertility treatment and the types of fertility treatment sought within a population-based sample. We analyzed data from the cross-sectional Pregnancy...

Infertility > Epidemiology > Treatment UtilizationInfertility > ART > Population-Based OutcomesResearch Methodology > Cross-Sectional Studies > Survey Design

The use of hormonal contraceptive agents and mood disorders in women

Svendal G et al., 2012 Journal of Affective Disorders

Background: Mood disorders are a major cause of disability in developed countries, and contraceptive agents among the most widely used medications. The relationship between contraceptive agents and mo...

Contraception/Comparison > Side Effects > Mood DisordersContraception/Comparison > Hormonal Contraception > Progestin-OnlyContraception/Comparison > Hormonal Contraception > Combined Oral Contraceptives

Effects of hormonal contraception on vaginal flora

De Seta F et al., 2012 Contraception

Background: The sector of the market that deals with contraception offers a long list of different contraceptive methods. Within the estroprogestinic choice, the routes of administration are oral, tra...

Contraception/Comparison > Side Effects > Vaginal MicrobiomeContraception/Comparison > Hormonal Contraception > Vaginal RingGeneral OB/GYN > Vaginal Health > Infection Prevention

In vitro fertilisation for unexplained subfertility

Pandian Z et al., 2012 The Cochrane Database of Systematic Reviews

Background: In vitro fertilisation (IVF) is a widely accepted treatment for unexplained infertility (NICE 2004), which affects up to a third of all infertile couples. With estimated live birth rates (...

Infertility > ART > IVF EffectivenessInfertility > Unexplained Infertility > Treatment ComparisonResearch Methodology > Systematic Reviews > Cochrane Reviews

Selective salpingography and tubal catheterization in infertile women

El Fekih C et al., 2012 La Tunisie Medicale

Background: Use of selective salpingography (SS) and fallopian tube catheterization (TC) has revolutionized the diagnosis and treatment of proximal tubal infertility. Aim: To evaluate results of wome...

Infertility > Tubal Factor > Tubal CatheterizationDiagnostics > Tubal Assessment > Selective SalpingographySurgery > Minimally Invasive > Tubal Recanalization

Oral micronized progesterone for vasomotor symptoms--a placebo-controlled randomized trial in healthy postmenopausal women

Hitchcock CL et al., 2012 Menopause (New York, N.Y.)

Objective: The aim of this study was to compare oral micronized progesterone (progesterone) with placebo as therapy for postmenopausal hot flushes and night sweats (vasomotor symptoms [VMS]). Methods...

Perimenopause/Menopause > Vasomotor Symptoms > Progesterone TherapyPerimenopause/Menopause > Treatment > Bioidentical HormonesResearch Methodology > Randomized Controlled Trials > Placebo-Controlled

Body weight and composition in users of levonorgestrel-releasing intrauterine system

Dal'Ava N et al., 2012 Contraception

Background: There is little information about body weight and body composition (BC) among users of the levonorgestrel-releasing intrauterine system (LNG-IUS). The aim of this study was to evaluate bod...

Contraception/Comparison > Side Effects > Weight and Body CompositionContraception/Comparison > Hormonal Contraception > Levonorgestrel IUSContraception/Comparison > Non-Hormonal Methods > Copper IUD

Hysteroscopic treatment of the cesarean-induced isthmocele in restoring infertility

Florio P et al., 2012 Current Opinion in Obstetrics & Gynecology

PURPOSE OF Review: To review the treatments of the cesarean-induced isthmocele in restoring infertility, associated techniques, and the risks of complications associated with their use. Recent Finding...

Surgery > Hysteroscopy > Isthmocele RepairInfertility > Secondary Infertility > Cesarean Scar DefectGeneral OB/GYN > Cesarean Section > Long-Term Complications

Low-dose lisinopril in normotensive men with idiopathic oligospermia and infertility: a 5-year randomized, controlled, crossover pilot study

Mbah AU et al., 2012 Clinical Pharmacology and Therapeutics

The outcomes of drug treatment for male infertility remain conjectural, with controversial study results. Our pilot study employed a randomized, placebo-controlled, crossover methodology with intentio...

Andrology > Medical Treatment > ACE Inhibitors for OligospermiaInfertility > Male Factor > Idiopathic Oligospermia TreatmentResearch Methodology > Randomized Controlled Crossover Trial > Male Infertility

Ultrastructural interaction between spermatozoon and human oviductal cells in vitro

Vigil P et al., 2012 Journal of Electron Microscopy

The oviduct is an important organ for successful mammalian reproduction. In this work, human oviducts were inseminated and their explants analyzed using scanning electron microscopy in order to study,...

Infertility > Reproductive Physiology > Sperm-Oviduct InteractionDiagnostics > Imaging > Electron Microscopy Reproductive TractReproductive Endocrinology > Gamete Biology > Sperm Transport and Reservoir

Menstrual bleeding patterns among regularly menstruating women

Dasharathy SS et al., 2012 American Journal of Epidemiology

Menstrual bleeding patterns are considered relevant indicators of reproductive health, though few studies have evaluated patterns among regularly menstruating premenopausal women. The authors evaluate...

Menstrual CycleGeneral OB/GYN

The effects of injectable hormonal contraceptives on HIV seroconversion and on sexually transmitted infections

Wand H et al., 2012 AIDS

Objectives: To investigate the association between hormonal contraceptives and risk of HIV-1 seroconversion and prevalence of other sexually transmitted infections. Design: Prospective cohort. Method...

Contraception/Comparison > Injectable Contraceptives > HIV and STI RiskGeneral OB/GYN > Sexually Transmitted Infections > Contraceptive-Associated RiskContraception/Comparison > Safety > Infectious Disease Susceptibility

Clinician perceptions of providing natural family planning methods in Title X funded clinics

Kelly PJ et al., 2012 Journal of Midwifery & Women's Health

INTRODUCTION: Natural family planning (NFP) methods are effective for contraception with proper and consistent use. However, only 1% of patients at federally funded Title X family planning clinics sel...

Body Literacy > Education > Clinician Training and PerspectivesFertility Awareness > Access and Provision > Title X Clinic ImplementationRRM Methods > Natural Family Planning > Provider Barriers and Facilitators