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Hormonal Contraception and Breast Cancer Risk

White ND 2018 American journal of lifestyle medicine

Contemporary hormonal contraception formulations contain lower doses of estrogen, have new synthetic progestin components, and provide novel methods of delivery that have not been studied extensively ...

Breast Cancer RiskHormonal Contraception AssociationContemporary Contraceptive Safety

Achieving Pregnancy Using Primary Care Interventions to Identify the Fertile Window

Bouchard TP et al. 2018 Open Access Frontiers in Medicine

Objective: To determine the effectiveness of achieving pregnancy with focused intercourse in the fertile window identified using natural fertility indicators. Methods: 24-cycle prospective effectiven...

Fertile Window IdentificationPrimary Care Pregnancy AchievementNatural Fertility Indicator Effectiveness

Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

Kristensen DM et al. 2018 Proceedings of the National Academy of Sciences of the United States of America

Concern has been raised over increased male reproductive disorders in the Western world, and the disruption of male endocrinology has been suggested to play a central role. Several studies have shown ...

NSAID Effects on Testicular FunctionIbuprofen-Induced HypogonadismIn Vivo/Ex Vivo Testicular Study

24-Month Metformin Improves PCOS Menses, Hormones, and Metabolism

Carpentier PA 2018 Journal of Clinical Endocrinology & Metabolism

Context: The long-term effects of metformin in women with polycystic ovarian syndrome (PCOS) are inadequately studied. Objective: The effects of metformin on women with PCOS during 24 months with res...

Metformin TherapyTestosterone and LHLong-Term Treatment Outcomes

A document analysis of 'Adverse incidents in fertility clinics: lessons to learn' reports published by the Human Fertilisation and Embryology Authority between 2010-2015

Steen J 2018 Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

BACKGROUND: The fertility clinic is an environment in which significant adverse incidents are potentially catastrophic. The Human Fertilisation and Embryology Authority (HFEA) publishes an annual repo...

Adverse Incident ReportingThematic AnalysisFertility Clinic Quality

Adjuvant administration of 17-α-hydroxy-progesterone caproate in women with three or more second trimester pregnancy losses undergoing cervical cerclage is no more effective than cerclage alone

Samson FD et al. 2018 Journal of perinatal medicine

OBJECTIVE: To investigate the role of adjuvant 17-α-hydroxy-progesterone caproate (17OHP-C) in reducing the risk of preterm delivery <34 weeks and adverse perinatal outcomes in women with ≥3 second tr...

Cervical InsufficiencyProgesterone TherapyPreterm Birth Prevention

DIR Jahrbuch 2017 (Deutsches IVF-Register Annual Report 2017)

Deutsches IVF-Register e.V. 2018 Deutsches IVF-Register Jahrbuch

Annual report (Jahrbuch) of the Deutsches IVF-Register (DIR) for treatment year 2017. DIR is the German national IVF/ICSI registry, founded 1982 — the oldest continuously operating ART registry. Volun...

Prolactin and Autoimmunity

Borba VV et al. 2018 Frontiers in immunology

The great asymmetry of autoimmune diseases between genders represents one of the most enigmatic observations among the mosaic of autoimmunity. Sex hormones are believed to play a crucial role on this ...

Higher TSH Levels Within the Normal Range Are Associated With Unexplained Infertility

Orouji Jokar T et al. 2017 The Journal of Clinical Endocrinology and Metabolism

CONTEXT: Unexplained infertility (UI), defined as the inability to conceive after 12 months of unprotected intercourse with no diagnosed cause, affects 10% to 30% of infertile couples. An improved und...

Subclinical Hypothyroidism and TSHTSH Threshold for FertilityThyroid Screening in Infertility Workup

Ovulation, a sign of health

Vigil P et al. 2017 The Linacre Quarterly

The concept of the ovarian continuum can be understood as a process that occurs during a woman's lifetime and begins during intrauterine life with fertilization. Women start their reproductive years w...

Women's Lifespan HealthHealth Indicator Beyond FertilityLifespan Hormonal Health

Contemporary Hormonal Contraception and the Risk of Breast Cancer

Mørch LS et al. 2017 The New England Journal of Medicine

BACKGROUND: Little is known about whether contemporary hormonal contraception is associated with an increased risk of breast cancer. METHODS: We assessed associations between the use of hormonal cont...

Breast Cancer RiskCombined Oral ContraceptivesProgestin-Only Methods

Relationship Between the Menstrual Cycle and Timing of Ovulation Revealed by New Protocols: Analysis of Data from a Self-Tracking Health App

Sohda S et al. 2017 Open Access Journal of Medical Internet Research

Background: There are many mobile phone apps aimed at helping women map their ovulation and menstrual cycles and facilitating successful conception (or avoiding pregnancy). These apps usually ask user...

Self-Tracking App Ovulation AnalysisApp-Based Population DataMobile App Menstrual Cycle Protocols

Association of Hormonal Contraception With Suicide Attempts and Suicides

Skovlund CW et al. 2017 The American Journal of Psychiatry

Objective: The purpose of this study was to assess the relative risk of suicide attempt and suicide in users of hormonal contraception. Method: The authors assessed associations between hormonal contr...

Mental HealthCombined Oral ContraceptivesProgestin-Only Methods

The International Glossary on Infertility and Fertility Care, 2017

Zegers-Hochschild F et al. 2017 Human Reproduction (Oxford, England)

STUDY Question: Can a consensus and evidence-driven set of terms and definitions be generated to be used globally in order to ensure consistency when reporting on infertility issues and fertility care...

International Consensus Glossary 2017Reproductive Medicine DefinitionsFertility Care Terminology

Teaching OB/GYN residents bioethics within a Catholic healthcare context

Steele A 2017 Issues in Law & Medicine

Residents entering training in the specialty of Obstetrics and Gynecology (OB/GYN) often have misconceptions as to what medical interventions Roman Catholic healthcare institutions prohibit, and why c...

Medical EducationResidency TrainingInstitutional Frameworks

Endometriosis, especially mild disease: a risk factor for miscarriages

Kohl Schwartz AS et al. 2017 Fertility and Sterility

Objective: To investigate the prevalence of miscarriage in women with endometriosis (WwE) compared with disease-free control women (CW). Design: Cross-sectional analysis nested in a retrospective obse...

Miscarriage RiskMild vs SevereEndometriosis-Related Pregnancy Loss

Stress and the HPA Axis: Balancing Homeostasis and Fertility

Joseph DN et al. 2017 International journal of molecular sciences

An organism's reproductive fitness is sensitive to the environment, integrating cues of resource availability, ecological factors, and hazards within its habitat. Events that challenge the environment...

The Future of Cesarean Delivery Rates in the United States

Clapp MA et al. 2017 Clinical Obstetrics and Gynecology

The US cesarean delivery rate remains 30%-32%. Increases in maternal age, obesity, and diabetes put upward pressure on this rate. Alternatives to cesarean delivery, vaginal birth after cesarean (VBAC)...

Rate TrendsCesarean Section ReductionUtilization Barriers

Osteopenia and Osteoporosis in Female Athletes

MacKnight JM 2017 Clinics in sports medicine

Disorders of bone density are especially prevalent among athletic women. The severity of bone loss ranges from osteopenia to frank osteoporosis. In female athletes, a higher incidence of osteoporosis ...