Newest scholarly works
Camera trocar lifting in office gasless laparoscopic sterilization under local anesthesia Acta obstetricia et gynecologica Scandinavica · 2010 Systematic review and metaanalysis of intraperitoneal instillation of local anesthetics for reduction of pain after gynecologic laparoscopy Journal of minimally invasive gynecology · 2012 Ultrasound Visceral Slide Assessment to Evaluate for Intra-abdominal Adhesions in Patients Undergoing Abdominal Surgery - A Systematic Review and Meta-analysis Journal of minimally invasive gynecology · 2021
All works
Original research
Systematic Mapping of the Abdomen and Pelvis (S-MAP) IIRRM 2026 · poster A three-axis framework for reproductive impairment IIRRM 2026 · poster The ART Reporting Completeness (ARC) Framework IIRRM 2026 · poster
All original research
Get a free library card
Save papers, follow topics, and connect the library to Claude or ChatGPT.
Sign up free
Commentary
Where Did the Vitamin A Go? What Changed in Cereal, Milk and the American Plate Naomi Whittaker, MD and Pam Schoenfeld, MS, RD, LDN · Oct 20
All 22 guides Plain-language guides to the methods, the conditions, and what the evidence shows.
All commentary
Breaking Up with IVF Free for membersMidwife and former front-line IVF clinician Dr. Jennifer Mercier joins Dr. Naomi Whittaker for a candid Save the Uterus Club conversation. Masterclass in Endometriosis & Surgery 9 sectionsComprehensive guide for patients preparing for endometriosis surgery. Hormones Through the Lifespan Free for membersA comprehensive overview of hormonal health across a woman's life, menstrual cycles, common conditions, and the transition to menopause, presented by Dr. Ana Garcia, OB/GYN.
All 20 courses Endometriosis For clinicians
Member courses and live calls
Join Save the Uterus Club: live calls with Dr. Whittaker, member courses, discussion.
Become a member
Save the Uterus Club
Save the Uterus Club The community and collaboration arm of RRM Academy: live calls, new research, advocacy taking shape. Become a member

Lifestyle and Environment Sleep and Circadian Health

Association between adverse perinatal outcomes and sleep disturbances during pregnancy: a systematic review and meta-analysis

Yang Z, Zhu Z, Wang C, Zhang F, Zeng H

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2022
DOI 10.1080/14767058.2020.1711727 PMID 31902261

Abstract

Background

Due to physiological and hormonal factors, sleep disturbances are prevalent in the obstetric population. Multiple studies have evaluated the relationship between sleep disturbances and perinatal outcomes, with inconsistent results. The purpose of this systematic review and meta-analysis was to further assess the overall relationship between four types of sleep disturbances (snoring, obstructive sleep apnea, extreme sleep duration, and poor sleep quality) and adverse perinatal outcomes.

Methods

We performed electronic searches in PubMed, Embase, the Cochrane Library, CNKI, VIP, and Wanfang Data in February 2019 to identify studies that assessed adverse perinatal outcomes among expectant mothers with sleep disturbances.

Results

In total, 5044 studies were identified in the initial search and 65 met the defined criteria. Pooled analysis showed that sleep disturbances were associated with an increased risk for preeclampsia (aOR: 2.77; 95% CI: 1.81-4.24), gestational diabetes mellitus (aOR: 1.96; 95% CI: 1.62-2.38), cesarean delivery (aOR: 1.99; 95% CI: 1.70-2.33), depression (aOR: 3.98; 95% CI: 2.74-5.77) and preterm birth (aOR: 1.95; 95% CI: 1.55-2.45).

Conclusions

The four studied sleep disturbances (OSA, snoring, extreme sleep duration and poor sleep quality) during pregnancy were associated with adverse perinatal outcomes. Expectant mothers should be advised to practice healthy sleep hygiene measures.

Topics

By this author

Related research

Lifestyle and Environment › Sleep and Circadian Health › Sleep Quality · Pregnancy › Pregnancy Complications › Hypertensive Disorders · Birth and Delivery › Birth Outcomes › Maternal Morbidity
Ziyi Yang, Ziyu Zhu, Chunyi Wang, Fan Zhang, Huan Zeng
Z Yang, Z Zhu, C Wang, F Zhang, H Zeng
PMID 31902261 31902261 DOI 10.1080/14767058.2020.1711727 10.1080/14767058.2020.1711727 Yang et al. 2022, Yang 2022

Learn

Resources

Tools

Help

Candid Platinum Transparency 2026

RRM Academy is a 501(c)(3) nonprofit providing free and low-cost education in restorative reproductive medicine for patients and healthcare professionals.

This site is an educational resource and does not provide medical advice. Inclusion of a study does not imply endorsement of its findings. Always consult a qualified healthcare provider for diagnosis and treatment.

© 2026 RRM Academy · All Rights Reserved

Restorative Reproductive Medicine Foundation · 3401 Hartzdale Dr, Ste 103B PMB 3518, Camp Hill, PA 17011 · EIN: 93-4594315
Sitemap AI Instructions Developers Terms of Use Medical Disclaimer Privacy Policy