A study was conducted to determine the accuracy and reliability of the Home Ovarian Monitor for measuring estrone glucuronide (E1G) and pregnanediol glucuronide (PdG) during ovulatory cycles as a mean...
OBJECTIVE: To investigate the relation between intra-abdominal fat distribution and metabolic disorders in nonobese patients with the polycystic ovary syndrome (PCOS).
DESIGN: Prospective case-contro...
PCOS > Metabolic Features > Insulin ResistancePCOS > Metabolic Features > Visceral AdiposityPCOS > Diagnosis > Body Composition Assessment
Treatment for infertility using assisted reproductive technologies (ART) is highly successful and has been used to help a steadily growing number of couples worldwide. In 1999, in the United States, m...
Contraception/Comparison > ART Outcomes > Fetal and Neonatal RisksInfertility > Assisted Reproduction > Adverse OutcomesResearch Methodology > Study Design > Confounders in ART Studies
OBJECTIVE: To assess the day-specific and cycle-specific probabilities of conception leading to clinical pregnancy, in relation to the timing of intercourse and vulvar mucus observations.
METHODS: Th...
OBJECTIVE: To confirm that hCG levels in follicular fluid and serum would be comparable between i.m. and s.c. administration of purified hCG.
DESIGN: In a prospective study, serum and follicular flui...
Objective: To evaluate the effects of laparoscopic ovarian wedge resection on hormonal and metabolic parameters of polycystic ovary syndrome (PCOS) and to compare profiles of women who achieved pregna...
PCOS > Surgical Treatment > Ovarian Wedge ResectionPCOS > Metabolic Features > Insulin and Lipid ProfilesSurgery > Laparoscopic Procedures > Ovarian Surgery for PCOS
OBJECTIVE: To investigate the possibility of direct effects of metformin on ovarian steroidogenesis.
DESIGN: Cultured ovarian cells.
SETTING: Academic research environment.
PATIENT(S): Women underg...
PCOS > Medical Treatment > MetforminReproductive Endocrinology > Ovarian Steroidogenesis > Drug EffectsPCOS > Pathophysiology > Androgen Production
To review the use of hCG and to describe the clinical benefit of recombinant hCG (r-hCG) based on the published results of prospective, randomized studies. Review of published articles. Tertiary infer...
OBJECTIVE: To determine the number of embryos stored at assisted reproductive technology (ART) clinics in the United States and their current disposition.
DESIGN: A targeted survey instrument sent by...
Ethics/Philosophy > Embryo Status > Cryopreserved Embryo DispositionInfertility > Assisted Reproductive Technology > IVF Embryo StorageResearch Methodology > Survey Studies > ART Practice Surveys
Mettler L et al., 2003JSLS : Journal of the Society of Laparoendoscopic Surgeons
BACKGROUND AND OBJECTIVE: Laparoscopy is the standard method to visually identify endometriotic lesions under magnification within and outside the minor pelvis. The aim of this study was to analyze th...
A discrepancy exists between the interest in modern methods of natural family planning (NFP) and their actual use in developed countries. To explore reasons for this discrepancy, we analyzed data from...
This cross-sectional cohort study of 5566 women and 2187 men 50 years of age and older in the population-based Canadian Multicentre Osteoporosis Study was conducted to determine whether reported past ...
OBJECTIVE: In women suffering from polycystic ovary syndrome (PCOS), correction of hyperinsulinemia results enhances spontaneous ovulation or alternatively, the responsiveness to ovulation induction a...
Martin JA et al., 2003National Vital Statistics Reports : From the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System
OBJECTIVES: This report presents 2001 data on U.S. births according to a wide variety of characteristics. Data are presented for maternal demographic characteristics including age, live-birth order, r...
General OB/GYN > Vital Statistics > US Birth DataPregnancy > Epidemiology > National Birth TrendsPregnancy > Preterm Birth > Population-Level Trends
Yildirim M et al., 2003European Journal of Obstetrics, Gynecology, and Reproductive Biology
OBJECTIVE: To determine the effects of ovarian wedge resection by minilaparotomy in infertile patients with polycystic ovarian syndrome (PCOS).
STUDY DESIGN: One hundred and thirty-four anovulatory p...
da Fonseca EB et al., 2003American Journal of Obstetrics and Gynecology
OBJECTIVE: The purpose of this study was to evaluate the effect of prophylactic vaginal progesterone in decreasing preterm birth rate in a high-risk population.
STUDY DESIGN: A randomized, double-bli...
Objective: To determine the efficacy of L-carnitine therapy in selected cases of male factor infertility.
Design: Placebo-controlled, double-blind, crossover trial.
Setting: University tertiary referr...
Andrology > Medical Treatment > Carnitine SupplementationAndrology > Semen Analysis > Sperm Motility ParametersInfertility > Male Factor > Nutritional Therapy
Makino I et al., 2003Biochemical and Biophysical Research Communications
Adrenomedullin (AM) gains its bioactivity by amidation at its C-terminal, forming "mature AM." The mature AM and the expression of AM receptor component mRNAs, receptor activity-modifying protein 2 an...
Buchweitz O et al., 2003The Journal of the American Association of Gynecologic Laparoscopists
STUDY OBJECTIVE: To evaluate the reliability of diagnosing minimal and mild endometriosis under routine conditions, and to determine to what extent disease activity is taken into account.
DESIGN: Ret...
Background: Hormonal contraceptives have been associated with increased risk of HIV acquisition.
Methods: The association between hormonal contraception use and HIV acquisition was assessed in a rura...
Contraception/Comparison > Hormonal Contraception > HIV RiskContraception/Comparison > Injectable Contraceptives > Health OutcomesResearch Methodology > Epidemiology > Population-Based Cohort
McCartney CR et al., 2003Seminars in Reproductive Medicine
Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism and chronic anovulation. Although the etiology of PCOS is unknown, perturbations of gonadotropin secretion are one of t...
OBJECTIVE: To review the effectiveness of metformin in restoring regular menstrual cycles and ovulation and achieving pregnancy in women with polycystic ovary syndrome (PCOS).
DESIGN: Systematic revi...
Stanford JB et al., 2002American Journal of Obstetrics and Gynecology
There are many potential mechanisms of action for the intrauterine device (IUD), which vary by type of IUD (inert, copper, or hormonal). This paper reviews the evidence for each potential mechanism of...
Zimmermann MB et al., 2002Thyroid : Official Journal of the American Thyroid Association
Several minerals and trace elements are essential for normal thyroid hormone metabolism, e.g., iodine, iron, selenium, and zinc. Coexisting deficiencies of these elements can impair thyroid function. ...
OBJECTIVE: To investigate the effects of reduction of insulin resistance and hyperinsulinemia associated with the polycystic ovary syndrome (PCOS) on FSH-stimulated ovarian aromatase activity.
DESIGN...
PCOS > Medical Treatment > MetforminPCOS > Pathophysiology > Insulin Resistance and HyperandrogenismReproductive Endocrinology > Ovarian Steroidogenesis > Aromatase Activity
Unlühizarci K K et al., 2002Fertility and Sterility
Hirsutism is a very common clinical problem encountered in daily practice, and, unfortunately, its treatment is far from satisfactory. In several studies, antiandrogens were given in combination with ...
The incidence of Chlamydia trachomatis (Ct) infection and the possible correlation between couples presenting with first-trimester spontaneous abortions and active Ct infection was assessed. Additiona...
Infertility > Infectious Causes > Chlamydia TrachomatisPregnancy > Early Pregnancy Loss > Infectious EtiologyDiagnostics > Infection Screening > Chlamydia Detection
Physicians who counsel women for preconception concerns are in an excellent position to give advice to couples regarding the optimal timing of intercourse to achieve pregnancy. The currently available...
CONTEXT: As a result of oocyte donation, women in their sixth decade of life are now able to conceive and carry pregnancies to term. However, little is known about pregnancy outcomes in this populatio...
Objective: To revise and expand the 1996 Osteoporosis Society of Canada clinical practice guidelines for the management of osteoporosis, incorporating recent advances in diagnosis, prevention and mana...
The (PD) peak day of cervical mucus is an important biologic marker for the self-determination of the optimal time of fertility in a woman's menstrual cycle. The purpose of this article is to provide ...
Background: Exercise programs improve balance, strength and agility in elderly people and thus may prevent falls. However, specific exercise programs that might be widely used in the community and tha...
Bone Health > Fall Prevention > Exercise InterventionsBone Health > Osteoporosis > Non-Pharmacological ManagementResearch Methodology > Randomized Controlled Trials > Exercise Interventions
Ablij H et al., 2002European Journal of Internal Medicine
C-reactive protein (CRP) is the prototype acute-phase protein, which can increase up to 1000-fold after the onset of a stimulus. Aside from its disputed role as a marker of infection and/or inflammati...
OBJECTIVE: To report a case of acute hemoperitoneum due to erosion of the uterine artery by an endometriotic lesion of the left ovary.
DESIGN: Case report and review of literature.
SETTING: Universi...
Endometriosis > Complications > Vascular ErosionSurgery > Laparoscopy > Emergency Conversion to LaparotomyEndometriosis > Case Reports > Acute Hemoperitoneum
OBJECTIVE: In vitro studies demonstrated that implantation on membranes (peritoneum, amniotic membranes) can take place if there are defects on the surface of the membranes. If these mechanisms play a...
Surgery > Laparoscopy > Timing and OutcomesEndometriosis > Treatment > Surgical RecurrenceMenstrual Cycle > Luteal Phase > Surgical Implications
Farquharson RG et al., 2002Obstetrics and Gynecology
OBJECTIVE: To compare the efficacy of low-dose aspirin alone versus low-dose aspirin plus low molecular weight heparin in pregnant women with antiphospholipid syndrome and recurrent miscarriage as pro...
OBJECTIVE: To review the evidence that polycystic ovary syndrome is a genetic disease.
DESIGN: Review of published literature.
RESULTS: The existing literature provides a strong basis for arguing th...
OBJECTIVE: To determine whether insulin resistance is associated with recurrent pregnancy loss (RPL).
DESIGN: Single center, case-controlled, prospective study.
SETTING: University-associated reprod...
Infertility > Recurrent Pregnancy Loss > Insulin ResistancePCOS > Metabolic Features > Insulin Resistance and PregnancyDiagnostics > Metabolic Testing > Fasting Insulin and Glucose
This multicenter study has produced a database of 7017 menstrual cycles contributed by 881 women. It provides improved knowledge on length and location of the "fertile window" (identified as of up to ...
Nestler JE, 2002Human Reproduction (Oxford, England)
Insulin resistance is a prominent feature of polycystic ovarian syndrome (PCOS), and women with the disorder are at increased risk for the development of other diseases that have been linked to insuli...
PCOS > Treatment > MetforminPCOS > Metabolic Features > Insulin Resistance and Diabetes RiskContraception/Comparison > Oral Contraceptives > Metabolic Effects in PCOS
OBJECTIVE: To prove that several days of low-dose hCG alone can be used to stimulate folliculogenesis, complete FSH-initiated follicle/oocyte maturation, and achieve pregnancy in assisted reproduction...
Zonana-Nacach A et al., 2002
Open Access
Salud Publica De Mexico
Objective: To assess risk factors associated with systemic lupus erythematosus (SLE) in the Mexican population.
MATERIAL AND Methods: A case-control study was conducted on June 1996, at the Reumathol...