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Impaired fecundity in the United States: 1982-1995

Chandra A et al., 1998 Family Planning Perspectives

CONTEXT: The 1995 National Survey of Family Growth (NSFG) provides new nationally representative data to test the accuracy of the commonly held assumption that impaired fecundity has been rising in th...

Infertility > Epidemiology > Population Trends in FecundityInfertility > Demographics > Age and Delayed ChildbearingResearch Methodology > Survey Studies > National Survey of Family Growth

Transrectal ultrasonography in the assessment of rectovaginal endometriosis

Fedele L et al., 1998 Obstetrics and Gynecology

OBJECTIVE: To evaluate the validity of transrectal ultrasonography in the assessment of rectovaginal endometriosis. METHODS: We compared the findings of transrectal ultrasonographic examination perfo...

Endometriosis > Diagnosis > Transrectal UltrasonographyDiagnostics > Imaging > Ultrasound for Deep EndometriosisEndometriosis > Deep Infiltrating > Rectovaginal Septum

Prevalence of ovarian endometriosis in epithelial ovarian cancer

Jimbo H et al., 1998 International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics

OBJECTIVE: The objective of this study was to examine the occurrence of ovarian endometriosis in epithelial ovarian cancer in Japan. METHOD: The presence of ovarian endometriosis was determined by re...

Endometriosis > Complications > Ovarian Cancer AssociationGeneral OB/GYN > Gynecologic Oncology > Endometriosis-Related Ovarian CancerEndometriosis > Epidemiology > Geographic Variation in Cancer Risk

Accuracy of the Ovulon fertility monitor to predict and detect ovulation

Fehring RJ et al., 1998 Journal of nurse-midwifery

The purpose of this pilot study was to correlate the three biologic markers of the Ovulon fertility monitor (a long-term predictive peak about 6 days before ovulation, a short-term predictive peak abo...

Fertility Awareness > Devices > Ovulon Fertility MonitorDiagnostics > Ovulation Detection > Vaginal Electrical ReadingsFertility Awareness > Methods > Technology-Assisted Monitoring

hCG, its free subunits and its metabolites. Roles in pregnancy and trophoblastic disease

Cole LA, 1998 The Journal of Reproductive Medicine

OBJECTIVE: To examine the structure and metabolism of human chorionic gonadotropin (hCG) and the effect of molecular heterogeneity on the immunodiagnosis and monitoring of gestational trophoblastic di...

Pregnancy > Biochemistry > hCG Structure and MetabolismDiagnostics > Biomarkers > hCG Measurement in Trophoblastic DiseaseGeneral OB/GYN > Gynecologic Oncology > Gestational Trophoblastic Disease

Role of opioid tone in the pathophysiology of hyperinsulinemia and insulin resistance in polycystic ovarian disease

Fulghesu AM et al., 1998 Metabolism: Clinical and Experimental

Hyperinsulinemia secondary to a poorly characterized disorder of insulin action is a feature of polycystic ovarian disease (PCOD). On the other hand, being generally admitted that opioids may play a r...

PCOS > Pathophysiology > Opioid Tone and Insulin ResistancePCOS > Treatment > Naltrexone Opioid BlockadeReproductive Endocrinology > Insulin Metabolism > PCOS Hyperinsulinemia

Maternal serum interleukin-6 concentration as a marker for impending preterm delivery

Murtha AP et al., 1998 Obstetrics and Gynecology

OBJECTIVE: To determine whether serum interleukin-6 concentrations predict impending preterm delivery. METHODS: Blood samples were collected from 130 gravidas at 22-34 weeks' gestation. The study gro...

Pregnancy > Preterm Birth > BiomarkersDiagnostics > Serum Biomarkers > Cytokine MeasurementPregnancy > Complications > Premature Rupture of Membranes

Expression of alpha6 and beta4 integrin subunits on human endometrium throughout the menstrual cycle and during early pregnancy

Lanteri E et al., 1998 Fertility and Sterility

OBJECTIVE: To evaluate the expression of alpha6 and beta4 integrin subunits on surface and glandular endometrium throughout the menstrual cycle and during early pregnancy. SETTING: Second Department ...

Reproductive Endocrinology > Endometrial Receptivity > Integrin ExpressionMenstrual Cycle > Endometrial Changes > Implantation WindowInfertility > Implantation > Molecular Markers

Premenopausal ovariectomy-related bone loss: a randomized, double-blind, one-year trial of conjugated estrogen or medroxyprogesterone acetate

Prior JC et al., 1998 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research

The purpose of this study was to contrast the effects of conventional estrogen treatment with medroxyprogesterone on cancellous and cortical bone change in the first year following premenopausal ovari...

Bone Health > Hormone Therapy > Estrogen vs ProgesteronePerimenopause/Menopause > Surgical Menopause > Bone LossResearch Methodology > Randomized Controlled Trials > Double-Blind Design

Women's interest in natural family planning

Lemaire JC et al., 1998 The Journal of Family Practice

BACKGROUND: In the United States, approximately 4% of women of reproductive age use natural family planning (NFP) to avoid pregnancy. It is unclear whether this low number is related to a lack of avai...

Fertility Awareness > Patient Perspectives > Interest and UtilizationBody Literacy > Public Awareness > Family Planning PreferencesResearch Methodology > Survey Studies > Reproductive Health

Neonatal assessment of babies conceived by in vitro fertilization

Fisch B et al., 1998 Journal of Perinatology : Official Journal of the California Perinatal Association

PROBLEM: Neonatal outcome of in vitro fertilization (IVF) pregnancies has been described by different authors, but several issues have yet to be resolved. The aim of the present study was to evaluate ...

Pregnancy > Neonatal Outcomes > Assisted ReproductionInfertility > IVF Outcomes > Neonatal AssessmentGeneral OB/GYN > Congenital Anomalies > ART-Related Risk

Design of the Women's Health Initiative clinical trial and observational study. The Women's Health Initiative Study Group

Women's Health Initiative Study Group, 1998 Control Clin Trials

The Women's Health Initiative (WHI) is a large and complex clinical investigation of strategies for the prevention and control of some of the most common causes of morbidity and mortality among postme...

General OB/GYN > Women's Health > Postmenopausal Disease PreventionResearch Methodology > Clinical Trial Design > Factorial DesignPerimenopause/Menopause > Hormone Therapy > Large-Scale Trials

Differential behavioral effects of gonadal steroids in women with and in those without premenstrual syndrome

Schmidt PJ et al., 1998 The New England Journal of Medicine

BACKGROUND: The symptoms of women with premenstrual syndrome improve in response to suppression of ovarian function, although these women have no evidence of ovarian dysfunction. We undertook a study ...

Menstrual Cycle > Premenstrual Syndrome > Hormonal MechanismsReproductive Endocrinology > Gonadal Steroids > Behavioral EffectsResearch Methodology > Randomized Controlled Trials > Crossover Design

Pharmacokinetics and pharmacodynamics of conjugated equine estrogens: chemistry and metabolism

Bhavnani BR, 1998 Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)

Conjugated equine estrogens (Premarin), are used extensively for estrogen replacement therapy and prevention of osteoporosis and cardiovascular disease in postmenopausal women. Premarin contains at le...

Reproductive Endocrinology > Estrogen Pharmacology > Conjugated Equine EstrogensPerimenopause/Menopause > Hormone Therapy > Estrogen MetabolismReproductive Endocrinology > Steroid Biochemistry > Estrogen Metabolites

Comparison of finasteride versus spironolactone in the treatment of idiopathic hirsutism

Erenus M et al., 1998 Fertility and Sterility

OBJECTIVE: To compare the efficacy of finasteride and spironolactone in the treatment of idiopathic hirsutism. DESIGN: Prospective, randomized, single-blind study. SETTING: A tertiary hirsutism clin...

Reproductive Endocrinology > Androgen Excess > Hirsutism TreatmentPCOS > Related Conditions > Idiopathic HirsutismResearch Methodology > Randomized Controlled Trials > Comparative Efficacy

Monitoring women at risk for preterm labor

Dyson DC et al., 1998 The New England Journal of Medicine

BACKGROUND: Preterm birth is a major cause of perinatal morbidity and mortality. Whether the rate of preterm birth can be reduced by frequent contact between nurses and pregnant women or home monitori...

Pregnancy > Preterm Labor > Monitoring and PreventionPregnancy > High-Risk Pregnancy > Twin PregnancyResearch Methodology > Randomized Controlled Trials > Obstetric Interventions

Practical diagnosis and treatment of premenstrual syndrome and premenstrual dysphoric disorder by psychiatrists and obstetricians/gynecologists in Japan

APGO, 1998 PCN reports : psychiatry and clinical neurosciences

Aim: To investigate and compare the diagnoses and treatment of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) from the perspectives of psychiatrists and obstetricians/gynecolog...

Menstrual Cycle > Premenstrual Syndrome > Diagnosis and TreatmentMenstrual Cycle > Premenstrual Dysphoric Disorder > PharmacotherapyGeneral OB/GYN > Clinical Practice Patterns > International Surveys

Current Research into the Role of Calcium in Treating PMS

Thys-Jacobs S, 1998 Nutrition in Clinical Practice

Herbal and related remedies are becoming increasingly popular in the United States. Although some of these products have been promoted as panaceas with little scientific data to support their use, cli...

Menstrual Cycle > Premenstrual Syndrome > Nutritional InterventionsMenstrual Cycle > Premenstrual Syndrome > Calcium Supplementation

Regulation of the human menstrual cycle

Chabbert Buffet N et al., 1998 Frontiers in neuroendocrinology

Our understanding of the regulation of the menstrual cycle has recently improved with the development of various tools of investigation. The cycle is now thought to be determined mainly by the ovary i...

Reproductive Endocrinology > Gonadotropin Secretion > Pulsatile LH PatternsMenstrual Cycle > Luteal Phase Defect > Gonadotropin EtiologyReproductive Endocrinology > Hypothalamic Dysfunction > Subclinical Disturbances

Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis

Dunaif A, 1997 Endocrine Reviews

It is now clear that PCOS is often associated with profound insulin resistance as well as with defects in insulin secretion. These abnormalities, together with obesity, explain the substantially incre...

PCOS > Pathophysiology > Insulin Resistance MechanismsReproductive Endocrinology > Insulin Signaling > Ovarian SteroidogenesisPCOS > Metabolic Complications > Diabetes and Cardiovascular Risk

What nurses should know about natural family planning

Trent AJ et al., 1997 Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN

Two common natural family planning (NFP) methods are the ovulation method based on characteristics of cervical mucus and the symptothermal method based on changes in cervical mucus, basal body tempera...

Fertility Awareness > Methods > Ovulation and Symptothermal MethodsFertility Awareness > Education > Nursing PracticeBody Literacy > Cervical Mucus Monitoring > Clinical Application

Metabolic changes induced by peroral oestrogen and transdermal oestradiol gel therapy

Karjalainen A et al., 1997 British Journal of Obstetrics and Gynaecology

OBJECTIVE: To investigate changes in plasma lipid and lipoprotein levels induced by peroral oestrogen replacement and transdermal oestradiol gel therapy. DESIGN: The effects of peroral oestradiol val...

Perimenopause/Menopause > Hormone Therapy > Estrogen Routes of AdministrationPerimenopause/Menopause > Hormone Therapy > Metabolic EffectsPerimenopause/Menopause > Cardiovascular Health > Lipid Profiles

Psychosocial predictors of depressive symptomatology level in postpartum women

Bernazzani O et al., 1997 Journal of Affective Disorders

This study explored a multifactorial model for the prediction of the intensity of depressive symptoms in postpartum women. Data were gathered from 213 pregnant women during the second trimester of pre...

Pregnancy > Mental Health > Postpartum Depression Risk FactorsPostpartum > Mental Health > Depressive SymptomatologyResearch Methodology > Statistical Methods > Path Analysis

Progesterone metabolite allopregnanolone in women with premenstrual syndrome

Rapkin AJ et al., 1997 Obstetrics and Gynecology

OBJECTIVE: To evaluate the anxiolytic 3alpha-5alpha-reduced progesterone metabolite allopregnanolone in the luteal phase of the menstrual cycle in women with premenstrual syndrome (PMS) and controls. ...

Menstrual Cycle > Premenstrual Syndrome > Neurosteroid PathophysiologyReproductive Endocrinology > Progesterone Metabolism > AllopregnanoloneMenstrual Cycle > Premenstrual Syndrome > Luteal Phase Hormones

Preterm birth and cerebral palsy. Predictive value of pregnancy complications, mode of delivery, and Apgar scores

Topp M et al., 1997 Acta Obstetricia Et Gynecologica Scandinavica

BACKGROUND: Preterm infants are at 8 times higher risk than term infants for pre- and perinatal brain damage, resulting in cerebral palsy. In this paper we have analysed the influence of prenatal and ...

Pregnancy > Preterm Birth > Cerebral Palsy Risk FactorsPregnancy > Delivery > Cesarean Section OutcomesResearch Methodology > Study Design > Register-Based Studies

Menstrual cyclicity after metformin therapy in polycystic ovary syndrome

Velázquez E et al., 1997 Obstetrics and Gynecology

OBJECTIVE: To assess the effect of insulin-lowering treatment on menstrual cyclicity in polycystic ovary syndrome (PCOS). METHODS: Forty oligoamenorrheic women with PCOS were recruited in a prospecti...

PCOS > Treatment > MetforminPCOS > Pathophysiology > Insulin ResistanceInfertility > Ovulation Induction > Insulin Sensitizing Agents

Transvaginal administration of progesterone

Fanchin R et al., 1997 Obstetrics and Gynecology

OBJECTIVE: To examine the endometrial effects of three different doses of progesterone administered vaginally. METHODS: Forty women 25-41 years old deprived of ovarian function received estradiol (E2...

Reproductive Endocrinology > Progesterone > Vaginal AdministrationReproductive Endocrinology > Endometrium > Secretory TransformationReproductive Endocrinology > Progesterone > First Uterine Pass Effect

Increased incidence of preeclampsia in women conceiving by intrauterine insemination with donor versus partner sperm for treatment of primary infertility

Smith GN et al., 1997 American Journal of Obstetrics and Gynecology

OBJECTIVE: Reports suggest that there is an increased incidence of preeclampsia after a previously normal pregnancy if there is a change in paternity. We hypothesize that there is a higher incidence o...

Infertility > Assisted Reproduction > Intrauterine InseminationPregnancy > Complications > PreeclampsiaPregnancy > Immunology > Paternal Antigen Exposure

Menstrual characteristics in women with and without endometriosis

Vercellini P et al., 1997 Obstetrics and Gynecology

OBJECTIVE: To assess menstrual blood loss and other menstrual characteristics prospectively in women with and without endometriosis. METHODS: Three hundred fifteen premenopausal women undergoing lapa...

Endometriosis > Symptoms > Menstrual CharacteristicsEndometriosis > Diagnosis > Menstrual Blood Loss AssessmentMenstrual Cycle > Disorders > Heavy Menstrual Bleeding

Fertility awareness in women attending a fertility clinic

Blake D et al., 1997 The Australian & New Zealand Journal of Obstetrics & Gynaecology

Eighty women attending for consultation at a tertiary referral fertility unit over a 3-month period were surveyed for their knowledge of fertility awareness and how they used this information to enhan...

Body Literacy > Education > Fertility Awareness KnowledgeFertility Awareness > Patient Knowledge > Fertile Window UnderstandingInfertility > Patient Education > Conception Timing Knowledge

Successful induction of ovulation in normogonadotrophic clomiphene resistant anovulatory women by combined naltrexone and clomiphene citrate treatment

Roozenburg BJ et al., 1997 Human Reproduction (Oxford, England)

Patients suffering from normogonadotrophic anovulation and infertility are initially treated with clomiphene citrate. Those who do not respond to clomiphene citrate usually receive gonadotrophin treat...

Infertility > Ovulation Induction > Naltrexone TherapyInfertility > Ovulation Induction > Clomiphene Resistance ManagementRRM Methods > Ovulation Restoration > Opioid Antagonist Treatment

Postpartum mood disorders: clinical perspectives

Pariser SF et al., 1997 Journal of Women's Health

Mood disorders are common in women. A prepregnancy personal history of mood disorder (bipolar or major depression), premenstrual syndrome, or (possibly) postpartum blues places a woman at high risk fo...

Pregnancy > Postpartum Complications > Postpartum Mood DisordersPostpartum > Mental Health > Depression and PsychosisGeneral OB/GYN > Psychiatry > Perinatal Mental Health

Pregnancy in infertile PCOD patients. Complications and outcome

Urman B et al., 1997 The Journal of Reproductive Medicine

OBJECTIVE: To evaluate the complications and outcome of pregnancy in women with polycystic ovary disease (PCOD). STUDY DESIGN: The course and outcome of 47 singleton pregnancies in women with well-do...

PCOS > Pregnancy Outcomes > Gestational DiabetesPCOS > Pregnancy Outcomes > Pregnancy-Induced HypertensionPregnancy > Complications > Metabolic Disorders in PCOS

Endometriosis-associated pelvic pain: evidence for an association between the stage of disease and a history of chronic pelvic pain

Stovall DW et al., 1997 Fertility and Sterility

OBJECTIVE: To track the severity and location of pelvic pain associated with endometriosis throughout the reproductive-age years and to evaluate the association between these pain parameters and the s...

Endometriosis > Symptoms > Chronic Pelvic PainEndometriosis > Staging > Disease Severity and OutcomesGeneral OB/GYN > Pain Management > Endometriosis-Associated Pain

Sexually transmitted diseases: global importance

Sciarra JJ, 1997 International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics

The worldwide incidence of sexually transmitted diseases (STDs) including the human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) continues to increase and represents a ma...

Infertility > Etiology > Sexually Transmitted InfectionsGeneral OB/GYN > Infectious Disease > Sexually Transmitted DiseasesInfertility > Prevention > STD Detection and Treatment

Determinants of abnormal gonadotropin secretion in clinically defined women with polycystic ovary syndrome

Taylor AE et al., 1997 The Journal of Clinical Endocrinology and Metabolism

Polycystic ovary syndrome (PCOS) is a heterogeneous disorder of reproductive age women characterized in its broadest definition by the presence of oligoamenorrhea and hyperandrogenism and the absence ...

PCOS > Pathophysiology > Gonadotropin Secretion AbnormalitiesReproductive Endocrinology > Neuroendocrinology > LH PulsatilityPCOS > Obesity > Body Composition and Hormonal Effects

The relationship between laparoscopic disease, pelvic pain and infertility; an unbiased assessment

Thornton JG et al., 1997 European Journal of Obstetrics, Gynecology, and Reproductive Biology

OBJECTIVES: To measure the relationship between laparoscopically detected pelvic pathology and pelvic pain or infertility. METHODS: Women undergoing diagnostic laparoscopy either for the investigatio...

Endometriosis > Diagnosis > Laparoscopic AssessmentEndometriosis > Symptoms > Pelvic Pain AssociationInfertility > Etiology > Endometriosis and Pelvic Pathology

The risk of preterm birth across generations

Porter TF et al., 1997 Obstetrics and Gynecology

OBJECTIVE: To examine the risk of preterm birth for mothers who themselves were born before term. METHODS: Data were taken from a linked data base of birth certificates composed of two cohorts: 1) a ...

Pregnancy > Preterm Birth > Intergenerational RiskPregnancy > Preterm Birth > Epidemiology and Risk FactorsResearch Methodology > Cohort Studies > Linked Database Analysis

Interleukin-6 and neopterin levels in serum of patients with preterm labour with and without infection

Oleszczuk J et al., 1997 European Journal of Obstetrics, Gynecology, and Reproductive Biology

We estimated the levels of interleukin 6 (IL-6) and neopterin, in serum of twelve nonpregnant (group A) and 28 pregnant women between 28-36 weeks of pregnancy. Group B consisted of eight patients with...

Pregnancy > Preterm Birth > Infection and Inflammation BiomarkersDiagnostics > Biomarkers > Interleukin-6 and Neopterin in PregnancyPregnancy > Preterm Birth > Immunological Mechanisms

Disturbances of menstruation in thyroid disease

Koutras DA, 1997 Annals of the New York Academy of Sciences

Both hyperand hypothyroidism may result in menstrual disturbances. In hyperthyroidism, amenorrhea was described as early as 1840 by von Basedow. The most common manifestation is simple oligomenorrhea ...

Menstrual Cycle > Disorders > Thyroid-Related Menstrual DisturbancesReproductive Endocrinology > Thyroid Disorders > Effects on MenstruationInfertility > Etiology > Thyroid Dysfunction and Anovulation

Expanding the availability and improving delivery of natural family planning services and fertility awareness education: providers' perspectives

Arévalo M, 1997 Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception

Despite the recognized benefits for clients and programs of providing natural family planning (NFP) services, few family planning programs offer NFP and few provide fertility awareness education. Furt...

Fertility Awareness > Service Delivery > Provider Perspectives and BarriersFertility Awareness > Program Integration > NFP in Family PlanningRRM Methods > Access and Availability > NFP Service Expansion

Body/self awareness and interpersonal communications: fundamental components of reproductive health awareness

Aumack-Yee K, 1997 Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception

To protect and advocate for their own reproductive health, people of all ages can greatly benefit from enhanced body/self awareness and strong interpersonal communication skills. Body/self awareness a...

Body Literacy > Education > Reproductive Health AwarenessBody Literacy > Self-Awareness > Body KnowledgeFertility Awareness > Education > Communication Skills

Natural family planning effectiveness: evaluating published reports

Lamprecht V et al., 1997 Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception

Objective: To equip the reader with the tools necessary to evaluate studies of natural family planning (NFP) effectiveness found in the literature and to make recommendations for future NFP effectiven...

Fertility Awareness > Effectiveness > Study EvaluationResearch Methodology > Study Design > Contraceptive EffectivenessFertility Awareness > Methods > Natural Family Planning

Changing behavior: a challenge for reproductive health awareness

Andreasen AR, 1997 Advances in Contraception : the Official Journal of the Society for the Advancement of Contraception

Social marketing applies commercial sector ideas to programs to change behavior. It involves a mindset that is customer-focused; a process that starts with customers and continually returns to them fo...

Body Literacy > Education > Behavior ChangeFertility Awareness > Education > Social MarketingBody Literacy > Health Promotion > Reproductive Health Awareness

Progesterone-induced immunosuppression

Schust DJ et al., 1997 Human reproduction (Oxford, England)

Progesterone is a known immunosupressant in humans and may be important in treatment regimens for women with immunological and endocrinological reproductive failure. The molecular mechanism of progest...

Reproductive Endocrinology > Progesterone > ImmunosuppressionInfertility > Immunological Factors > Progesterone TreatmentReproductive Endocrinology > Hormone Receptors > Progesterone Receptor Expression