Urman, B., Sarac, E., Dogan, L., & Gürgan, T. (1997). Pregnancy in infertile PCOD patients. Complications and outcome. The Journal of Reproductive Medicine, 42(8), 501-505.
Urman B, Sarac E, Dogan L, Gürgan T. Pregnancy in infertile PCOD patients. Complications and outcome. J Reprod Med. 1997;42(8):501-505.
Urman, B., et al. "Pregnancy in infertile PCOD patients. Complications and outcome." The Journal of Reproductive Medicine, vol. 42, no. 8, 1997, pp. 501-505.
To evaluate the complications and outcome of pregnancy in women with polycystic ovary disease (PCOD).
Study Design
The course and outcome of 47 singleton pregnancies in women with well-documented PCOD were compared with those in 100 healthy controls.
Results
Women with PCOD had a significantly higher body mass index as compared to the control group (P < .05); however, the proportion of lean versus obese subjects in the two groups was similar. The incidence of an abnormal glucose challenge test, gestational diabetes mellitus and pregnancy-induced hypertension was significantly increased in pregnant women with PCOD (P < .05). When lean PCOD subjects were compared with lean control subjects, the difference in the incidence of the above complications was still significant (P < .05). The incidence of pregnancy complications was similar when obese PCOD subjects were compared with obese controls.
Conclusion
Women with PCOD were at increased risk of gestational diabetes and pregnancy-induced hypertension, and this risk appeared to be independent of body mass index.