The Journal of Reproductive Medicine, 43(1), 3-10
To examine the structure and metabolism of human chorionic gonadotropin (hCG) and the effect of molecular heterogeneity on the immunodiagnosis and monitoring of gestational trophoblastic disease.
A review of the current medical literature concerning measurement of hCG and hCG-related molecules.
hCG molecules in gestational trophoblastic disease are more heterogeneous or degraded in serum and urine samples than in normal pregnancy.
Appropriate measurement and monitoring of hCG levels in gestational trophoblastic disease require an understanding of hCG structure and metabolism.
Cole, L. A. (1998). hCG, its free subunits and its metabolites. Roles in pregnancy and trophoblastic disease. *The Journal of reproductive medicine*, *43*(1), 3-10.
Cole LA. hCG, its free subunits and its metabolites. Roles in pregnancy and trophoblastic disease. J Reprod Med. 1998;43(1):3-10.
Cole, Louise A. "hCG, its free subunits and its metabolites. Roles in pregnancy and trophoblastic disease." *The Journal of reproductive medicine*, vol. 43, no. 1, 1998, pp. 3-10.
Biomarkers/blood/urine, Chorionic Gonadotropin/analysis/chemistry/metabolism/physiology, Circadian Rhythm, Epitopes/immunology, Female, Humans, Pregnancy/blood/physiology/urine, Reagent Kits, Diagnostic, Reproducibility of Results, Trophoblastic Neoplasms/blood/urine, Uterine Neoplasms/blood/urine, Biomarkers, Chorionic Gonadotropin, Epitopes, Reagent Kits, Diagnostic,