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Ovulation induction

March CM, 1993 The Journal of Reproductive Medicine

Induction of ovulation is indicated for anovulatory and amenorrheic women as well as for women who have an inadequate luteal phase. It is also indicated as a strategy for recruiting multiple follicles...

Infertility > Ovulation Induction > Pharmacological AgentsReproductive Endocrinology > Anovulation > Treatment ProtocolsInfertility > Unexplained Infertility > Controlled Ovarian Stimulation

Risk indicators for inflammatory bowel disease

Persson PG et al., 1993 International Journal of Epidemiology

We investigated the association between different risk indicators and inflammatory bowel disease in a case-control study based on the population of Stockholm County during 1980-1984. Information on ph...

Contraception/Comparison > Adverse Effects > Inflammatory Bowel DiseaseGeneral OB/GYN > Gastrointestinal Disease > Oral Contraceptive RiskResearch Methodology > Case-Control Study > Epidemiological Risk Factors

Evaluation of natural family planning programmes in Liberia and Zambia

Gray RH et al., 1993 Journal of Biosocial Science

Studies to evaluate use-effectiveness and cost-effectiveness of natural family planning (NFP) were conducted in Liberia and Zambia. The Liberian programme provided uni-purpose NFP services to 1055 cli...

Fertility Awareness > Program Evaluation > Developing CountriesFertility Awareness > Effectiveness > Use-Effectiveness RatesRRM Methods > Natural Family Planning > Cost-Effectiveness

Suboptimal progesterone production in pathologic pregnancies

Cunningham DS et al., 1993 The Journal of Reproductive Medicine

Serum progesterone (P) levels were determined at the time of routine prenatal registration (227 patients) or upon presentation for evaluation of vaginal bleeding and/or abdominopelvic cramping/pain (1...

Pregnancy > Early Pregnancy Loss > Progesterone DeficiencyDiagnostics > Hormonal Biomarkers > Progesterone ScreeningReproductive Endocrinology > Progesterone > Early Pregnancy Levels

Do tocolytic agents stop preterm labor? A critical and comprehensive review of efficacy and safety

Higby K et al., 1993 American Journal of Obstetrics and Gynecology

OBJECTIVE: Our aim was to determine the efficacy and safety of tocolytic agents currently used to treat premature labor. STUDY DESIGN: We carried out a comprehensive review of tocolytic agents in the...

Pregnancy > Preterm Labor > Tocolytic TherapyResearch Methodology > Systematic Review > Drug EfficacyGeneral OB/GYN > Pharmacology > Uterine Relaxants

Endocrine changes and clinical outcome after laparoscopic ovarian resection in women with polycystic ovaries

Campo S et al., 1993 Human Reproduction (Oxford, England)

Ovarian laparoscopic resection was applied to 23 sterile patients affected with polycystic ovarian disease (PCOD) resistant to different pharmacological treatments, in order to induce ovulation. After...

PCOS > Surgical Treatment > Laparoscopic Ovarian DrillingInfertility > Ovulation Induction > Surgical ApproachesReproductive Endocrinology > Androgens > Post-Surgical Hormonal Changes

Psychosocial stress as a cause of infertility

Wasser SK et al., 1993 Fertility and Sterility

An adaptive model for the evolution of reproductive failure predicted psychosocial stress to increase as anatomic causes of infertility decrease. The nonanatomic infertility group in our study reporte...

Infertility > Unexplained Infertility > Psychosocial FactorsInfertility > Etiology > Stress and ReproductionResearch Methodology > Case-Control Study > Infertility Risk Factors

Smoking and ovulation inhibitor in inflammatory bowel diseases

Katschinski B, 1993 Medizinische Klinik (Munich, Germany : 1983)

In a case-control study the effects of smoking and the use of oral contraceptives were examined in 83 patients with Crohn's disease and 37 patients with ulcerative colitis in comparison with members o...

Contraception/Comparison > Oral Contraceptives > Autoimmune Disease RiskContraception/Comparison > Side Effects > Gastrointestinal DiseaseResearch Methodology > Case-Control Study > Contraceptive Risk Assessment

Postpartum mood disorders. A startling contrast to the joy of birth

Knops GG, 1993 Postgraduate Medicine

More than half of new mothers may be affected by mood disorders after childbirth. Possible causes and recommended management depend on the type of disorder and its severity. In this article, Dr Knops ...

Postpartum > Mental Health > Postpartum DepressionPostpartum > Mental Health > Postpartum PsychosisGeneral OB/GYN > Postpartum Care > Mood Disorder Management

The Billings method

Delangue AF, 1993 Soins. Gynecologie, Obstetrique, Puericulture, Pediatrie

The Billings method, or cervical mucus method, is a natural family planning method developed during the 1970s by the Australian physicians John and Evelyn Billings. The method requires periodic abstin...

Fertility Awareness > Cervical Mucus Monitoring > Billings Ovulation MethodMenstrual Cycle > Biomarkers > Cervical Mucus PatternsBody Literacy > Fertility Signs > Mucus Observation Techniques

Oral contraceptives and reproductive factors in multiple sclerosis incidence

Villard-Mackintosh L et al., 1993 Contraception

Data from the Oxford.FPA prospective study show that oral contraceptive use and pregnancy have no discernible effect on the risk of developing multiple sclerosis (MS). Women of parity 0-2 developed MS...

Contraception/Comparison > Oral Contraceptives > Neurological OutcomesGeneral OB/GYN > Reproductive Risk Factors > Autoimmune DiseaseResearch Methodology > Prospective Cohort Studies > Contraceptive Outcomes

Norplant

Hilgers TW, 1993 The Linacre Quarterly
Contraception/Comparison > Hormonal Methods > ImplantsEthics/Philosophy > Catholic Medical Ethics > Contraceptive Evaluation

The familial risk of endometriosis

Moen MH et al., 1993 Acta obstetricia et gynecologica Scandinavica
Endometriosis > Epidemiology > Familial and Genetic RiskGeneral OB/GYN > Genetic Factors > Reproductive Disease Heritability

Human cervical mucus: relationship between biochemical characteristics and ability to allow migration of spermatozoa

Morales P et al., 1993 Human reproduction (Oxford, England)

Cervical mucus is produced throughout the menstrual cycle. Sperm migration, however, is possible only during the periovulatory period of the cycle. Cervical mucus is also produced during the amenorrho...

Menstrual Cycle > Cervical Mucus > Biochemical PropertiesFertility Awareness > Biomarkers > Cervical Mucus and Sperm InteractionPostpartum > Cervical Mucus > Sperm Migration Patterns

Oral contraceptive pill use and fractures in women: a prospective study

Cooper C et al., 1993 Bone

It has been suggested that use of the oral contraceptive pill by women confers protection against osteoporosis later in life. However, cross-sectional studies of bone density among pill users have yie...

Contraception/Comparison > Oral Contraceptives > Bone Health OutcomesBone Health > Fracture Risk > Hormonal Contraception EffectsResearch Methodology > Prospective Cohort Studies > Fracture Outcomes

Pharmacotherapy of preterm labor

Travis BE et al., 1993 Pharmacotherapy

Preterm labor is defined as the onset of uterine contractions in a woman who has completed less than 37 weeks of pregnancy. It may be due to maternal, placental, fetal, or idiopathic causes, and it is...

Pregnancy > Preterm Labor > Tocolytic PharmacotherapyPregnancy > Preterm Labor > Progesterone TherapyGeneral OB/GYN > Pharmacology > Tocolytic Agents

Human chorionic gonadotrophin (hCG) in the management of recurrent abortion; results of a multi-centre placebo-controlled study

Harrison RF, 1992 European Journal of Obstetrics, Gynecology, and Reproductive Biology

An international ten-centre double-blind trial comparing hCG with placebo in the management of habitual abortion was conducted. The dose regime for hCG used was 10,000 IU i.m. on first diagnosis of pr...

Pregnancy > Recurrent Pregnancy Loss > hCG TherapyReproductive Endocrinology > Hormonal Support > hCG in Early PregnancyResearch Methodology > Randomized Controlled Trials > Recurrent Miscarriage

Standardization of hysterosalpingography and selective salpingography: a valuable adjunct to simple opacification studies

Gleicher N et al., 1992 Fertility and Sterility

OBJECTIVE: To investigate the correlation between opacification and perfusion pressures during hysterosalpingography (HSG) and selective salpingography under the assumption that the latter may add to ...

Infertility > Diagnostics > HysterosalpingographyDiagnostics > Tubal Assessment > Selective SalpingographyInfertility > Tubal Factor > Tubal Patency Testing

Polycystic ovary syndrome and risk for myocardial infarction. Evaluated from a risk factor model based on a prospective population study of women

Dahlgren E et al., 1992 Acta Obstetricia Et Gynecologica Scandinavica

In order to estimate whether women with polycystic ovary syndrome (PCOS) have an increased risk of developing myocardial infarction, a risk factor model was applied on 33 women with PCOS and 132 age m...

PCOS > Comorbidities > Cardiovascular RiskPCOS > Metabolic Features > Obesity and LipidsGeneral OB/GYN > Preventive Health > Cardiovascular Disease in Women

Characteristics relating to ovarian cancer risk: collaborative analysis of 12 US case-control studies. II. Invasive epithelial ovarian cancers in white women. Collaborative Ovarian Cancer Group

Whittemore AS et al., 1992 American Journal of Epidemiology

Data collected from 2,197 white ovarian cancer patients and 8,893 white controls in 12 US case-control studies conducted in the period 1956-1986 were used to evaluate the relation of invasive epitheli...

General OB/GYN > Gynecologic Oncology > Ovarian Cancer Risk FactorsContraception/Comparison > Health Outcomes > Cancer RiskInfertility > Treatment Risks > Fertility Drug Safety

A prospective comparison of terbutaline and magnesium for tocolysis

Chau AC et al., 1992 Obstetrics and Gynecology

OBJECTIVE: To compare the tocolytic efficacy and side effects of parenteral and oral magnesium and terbutaline. METHODS: Ninety-eight patients in labor between 23-35 weeks were prospectively entered ...

Pregnancy > Preterm Labor > Tocolytic TherapyPregnancy > Complications > Preterm Delivery PreventionResearch Methodology > Clinical Trials > Prospective Controlled Trial

Steroid and peptide regulation of insulin-like growth factor-binding proteins secreted by human endometrial stromal cells is dependent on stromal differentiation

Giudice LC et al., 1992 The Journal of Clinical Endocrinology and Metabolism

Endometrial stromal cells undergo decidual transformation, in response to epidermal growth factor (EGF) and progesterone. Since insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) are...

Reproductive Endocrinology > Endometrial Physiology > Growth Factor RegulationReproductive Endocrinology > Hormonal Regulation > Progesterone Action on EndometriumMenstrual Cycle > Luteal Phase > Endometrial Decidualization

The effect of tocolytic agents (indomethacin and terbutaline) on fetal breathing and body movements: a prospective, randomized, double-blind, placebo-controlled clinical trial

Hallak M et al., 1992 American Journal of Obstetrics and Gynecology

OBJECTIVE: The null hypothesis of this study is that maternal administration of indomethacin or terbutaline will not affect fetal breathing and body movements. STUDY DESIGN: Thirty patients with a lo...

Pregnancy > Preterm Labor > Tocolytic TherapyPregnancy > Fetal Assessment > Fetal Biophysical EffectsResearch Methodology > Clinical Trials > Randomized Double-Blind Placebo-Controlled

Cumulative pregnancy rates in patients with apparently normal fertility and fertility-focused intercourse

Hilgers TW et al., 1992 The Journal of Reproductive Medicine

Fifty consecutive clients achieved pregnancy using a standardization modification of the Billings ovulation method (the Creighton Model Natural Family Planning System). Of 50 clients followed, 38 (76%...

NaProTECHNOLOGY > Fertility Care > Pregnancy AchievementFertility Awareness > Methods > Creighton Model SystemInfertility > Natural Methods > Fertility-Focused Intercourse

Obstetric outcome of in vitro fertilization pregnancies compared with normally conceived pregnancies

Tan SL et al., 1992 American Journal of Obstetrics and Gynecology

OBJECTIVE: To compare the obstetric outcome of in vitro fertilization pregnancies with normally conceived pregnancies. STUDY DESIGN: The obstetric outcome of in vitro fertilization pregnancies achiev...

Infertility > ART Outcomes > Obstetric ComplicationsPregnancy > Complications > ART-Related RisksInfertility > IVF > Pregnancy Outcome Comparison

Influence of corpus luteum age on the steroidogenic response to exogenous human chorionic gonadotropin in normal cycling women

Fritz MA et al., 1992 American Journal of Obstetrics and Gynecology

OBJECTIVE: The null hypothesis of this study is that the patterns of steroid secretion exhibited by the human corpus luteum in response to exogenous human chorionic gonadotropin stimulation are indepe...

Reproductive Endocrinology > Luteal Phase > Corpus Luteum FunctionReproductive Endocrinology > Hormonal Regulation > hCG StimulationInfertility > Luteal Phase Support > hCG Administration Timing

Treatment of premenstrual syndrome with fluoxetine: a double-blind, placebo-controlled, crossover study

Wood SH et al., 1992 Obstetrics and Gynecology

OBJECTIVE: Although its etiology is unknown, it has been hypothesized that premenstrual syndrome (PMS) is linked to a deficiency of central serotoninergic activity. In the present study, we evaluated ...

Menstrual Cycle > Premenstrual Syndrome > Pharmacologic TreatmentMenstrual Cycle > Premenstrual Syndrome > Serotonergic MechanismsResearch Methodology > Clinical Trials > Double-Blind Crossover Design

Puerperal psychoses: a clinical case study with follow-up

Benvenuti P et al., 1992 Journal of Affective Disorders

Thirty cases of post-partum psychotic disorders occurred between 1973 and 1987 and hospitalized at the Psychiatric Ward of Florence University were studied and followed up. A structured diagnostic int...

Pregnancy > Postpartum Complications > Puerperal PsychosisPostpartum > Mental Health > Postpartum Psychotic DisordersGeneral OB/GYN > Psychiatry > Mood Disorders in Pregnancy

Reproduction for the athletic woman. New understandings of physiology and management

Prior JC et al., 1992 Sports Medicine (Auckland, N.Z.)

A physically active and athletic lifestyle is not only a healthy but a fulfilling choice for women. Although there is extensive literature on 'athletic amenorrhoea' which implies that exercise causes ...

Reproductive Endocrinology > Hypothalamic Dysfunction > Exercise-Induced AmenorrheaBone Health > Bone Density > Progesterone and Bone MetabolismMenstrual Cycle > Ovulatory Disorders > Luteal Phase Deficiency in Athletes

Folates and post partum depression

Rouillon F et al., 1992 Journal of Affective Disorders

Hypofolatemia can cause psychiatric disturbances of a depressive nature. Pregnancy and delivery are often associated with hypofolatemia. This study was conducted to determine if hypofolatemia at day 3...

Postpartum > Mental Health > Postpartum DepressionPregnancy > Nutritional Factors > Folate and Maternal MoodGeneral OB/GYN > Postpartum Complications > Risk Factors for Depression

The incidence of cerebral palsy

Rosen MG et al., 1992 American Journal of Obstetrics and Gynecology

The clinician is often held responsible for obstetric events that are suspected of being related to cerebral palsy. To review the incidence of cerebral palsy and to aid the clinician in this situation...

Pregnancy > Neonatal Outcomes > Cerebral PalsyGeneral OB/GYN > Obstetric Complications > Intrapartum Risk AssessmentResearch Methodology > Epidemiology > Incidence Studies

Evaluation of sodium carboxymethylcellulose for prevention of adhesions after uterine trauma in ewes

Moll HD et al., 1992 American Journal of Veterinary Research

Efficacy of a 1% solution of sodium carboxymethylcellulose (CMC) infused into the peritoneal cavity of ewes was evaluated for prevention of intraperitoneal adhesions resulting from surgery of the repr...

Surgery > Adhesion Prevention > Barrier AgentsSurgery > Animal Models > Uterine Trauma and AdhesionsGeneral OB/GYN > Surgical Complications > Post-Operative Adhesions

Pregnancy following infertility

Bhalla AK et al., 1992 The Australian & New Zealand Journal of Obstetrics & Gynaecology

Pregnancies of 112 patients who had conceived after a history of a minimum of 2 years of infertility were compared to an equal number of matching controls without prior infertility to find out any ris...

Infertility > Pregnancy Outcomes > Obstetric ComplicationsPregnancy > High-Risk Pregnancy > Prior InfertilityGeneral OB/GYN > Pregnancy Complications > Antepartum Hemorrhage

The natural killer activity of peritoneal fluid lymphocytes is decreased in women with endometriosis

Oosterlynck DJ et al., 1992 Fertility and Sterility

OBJECTIVE: To investigate the local natural killer (NK) activity of the peritoneal fluid mononuclear cells (PFMC). DESIGN PATIENTS: In a prospective way, the NK activity (K562-assay) was measured in...

Endometriosis > Immunology > Natural Killer Cell ActivityEndometriosis > Pathophysiology > Peritoneal Fluid EnvironmentInfertility > Endometriosis-Related > Immune Dysfunction

Re: "Polycystic ovaries and the risk of breast cancer"

Toniolo P et al., 1992 American Journal of Epidemiology

Gammon and Thompson (1) recently reported in the Journal the results of an analysis of data from the Center for Disease Control's Cancer and Steroid Hormones Study to examine the association between a...

PCOS > Long-Term Health Risks > Breast Cancer RiskGeneral OB/GYN > Oncology > Breast Cancer Hormonal Risk FactorsReproductive Endocrinology > Endogenous Hormones > Cancer Association

Glucocorticoid treatment decreases sera embryotoxicity in endometriosis patients

Gómez E et al., 1992 Fertility and Sterility

OBJECTIVE: To investigate the effect of short-term glucocorticoid administration on embryotoxicity of sera from infertile patients with mild to moderate endometriosis. DESIGN: Prospective longitudina...

Endometriosis > Medical Treatment > Glucocorticoid TherapyEndometriosis > Pathophysiology > Embryotoxicity and AutoimmunityInfertility > Endometriosis-Related > Immunological Factors

A simple, safe technique for placement of the veress needle and trocar in laparoscopy

Hilgers TW, 1992 Journal of Laparoendoscopic Surgery

A simple technique of placing two Kocher clamps on the anterior rectus fascia for the elevation of the anterior abdominal wall during the insertion of the veress needle and the laparoscopic trocar is ...

Surgery > Laparoscopy > Trocar Placement TechniqueSurgery > Laparoscopy > Complication PreventionNaProTECHNOLOGY > Surgical Techniques > Laparoscopy

Significance of peritoneal macrophages on fertility in mice

Umesaki N et al., 1992 American Journal of Obstetrics and Gynecology

OBJECTIVE: To elucidate the role of peritoneal macrophages in infertility, we investigated how the presence of peritoneal macrophages would affect fecundity in mice. Moreover, we also studied the effe...

Infertility > Immunological Factors > Peritoneal MacrophagesReproductive Endocrinology > Cytokines > Interleukin-1 Embryo EffectsResearch Methodology > Animal Models > Mouse Fertility Studies

Comparison of cytokine levels and embryo toxicity in peritoneal fluid in infertile women with untreated or treated endometriosis

Taketani Y et al., 1992 American Journal of Obstetrics and Gynecology

OBJECTIVE: Our aim was to examine the relationship between the levels of cytokines in peritoneal fluid and its embryo toxicity. STUDY DESIGN: The levels of interleukin-1 and tumor necrosis factor wer...

Endometriosis > Pathophysiology > Peritoneal EnvironmentEndometriosis > Medical Treatment > Danazol and GnRH AgonistsInfertility > Immunological Factors > Cytokine Mediated

Early pregnancy wastage: the role of repetitive human chorionic gonadotropin supplementation during the first 8 weeks of gestation

Blumenfeld Z et al., 1992 Fertility and Sterility

OBJECTIVE: To determine if repetitive administration of hCG causes decreased pregnancy wastage rates in patients who are at a high risk of luteal inadequacy. DESIGN: Ovulation induction using human m...

Infertility > Recurrent Pregnancy Loss > hCG SupplementationReproductive Endocrinology > Luteal Phase Deficiency > TreatmentPregnancy > Early Pregnancy Support > Hormonal Supplementation

Pelvic inflammatory disease and fertility. A cohort study of 1,844 women with laparoscopically verified disease and 657 control women with normal laparoscopic results

Weström L et al., 1992 Sexually Transmitted Diseases

From 1960 10 1984, 2,501 women underwent diagnostic laparoscopy (index laparoscopy) because of a clinical suspicion of acute pelvic inflammatory disease (PID). Of these women, 1,844 had abnormal lapar...

Infertility > Tubal Factor > Pelvic Inflammatory DiseaseGeneral OB/GYN > Infectious Disease > PID Long-term OutcomesInfertility > Ectopic Pregnancy > Risk Factors

Assessment of the empty follicle syndrome by transvaginal sonography

Hilgers TW et al., 1992 Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine

The empty follicle syndrome was assessed using transvaginal ultrasonography in a group of 152 consecutive women with unmedicated menstrual cycles being studied because of primary or secondary infertil...

NaProTECHNOLOGY > Diagnostics > Transvaginal UltrasoundDiagnostics > Ovulation Assessment > Empty Follicle SyndromeInfertility > Ovulatory Dysfunction > Empty Follicle Syndrome

Myomectomy for fertility enhancement and preservation

Verkauf BS, 1992 Fertility and Sterility

OBJECTIVE: To review, evaluate, and synthesize current published reports assessing the value of abdominal myomectomy in infertile women and those desiring to preserve fertility potential. DATA IDENTI...

Surgery > Myomectomy > Fertility PreservationInfertility > Uterine Factor > Leiomyomata TreatmentSurgery > Abdominal Surgery > Myomectomy Outcomes

Oral contraceptive use and the risk of inflammatory bowel disease

Sandler RS et al., 1992 Epidemiology (Cambridge, Mass.)

We used rosters of the Crohn's and Colitis Foundation of America to identify potential cases and peer-nominated controls to explore the reported association between oral contraceptives and inflammator...

Contraception/Comparison > Side Effects > Inflammatory Bowel DiseaseContraception/Comparison > Oral Contraceptives > Autoimmune RiskResearch Methodology > Epidemiology > Case-Control Studies

Luteal function in infertile patients with endometriosis

Kusuhara K, 1992 American Journal of Obstetrics and Gynecology

OBJECTIVE: Our purpose was to determine whether infertile patients who have endometriosis show luteal phase defects. STUDY DESIGN: The luteal function in 24 infertile patients who had endometriosis w...

Endometriosis > Pathophysiology > Luteal Phase FunctionInfertility > Endometriosis-Related > Hormonal AssessmentReproductive Endocrinology > Luteal Phase Deficiency > Endometriosis Association

Oestriol in the prophylactic treatment of recurrent urinary tract infections in postmenopausal women

Kirkengen AL et al., 1992 Scandinavian Journal of Primary Health Care

A block randomized, double-blind, group-comparative, placebo-controlled study was conducted to assess the effect of oestriol on recurrent urinary tract infections in postmenopausal women. 40 women, me...

Perimenopause/Menopause > Hormone Therapy > Estriol TreatmentGeneral OB/GYN > Urinary Tract Infections > Postmenopausal PreventionResearch Methodology > Clinical Trials > Randomized Controlled Trial