Bhalla, A. K., Sarala, G., & Dhaliwal, L. (1992). Pregnancy following infertility. The Australian & New Zealand journal of obstetrics & gynaecology, 32(3), 249-251. https://doi.org/10.1111/j.1479-828x.1992.tb01959.x
Bhalla AK, Sarala G, Dhaliwal L. Pregnancy following infertility. Aust N Z J Obstet Gynaecol. 1992;32(3):249-251. doi:10.1111/j.1479-828x.1992.tb01959.x
Bhalla, ashish K., et al. "Pregnancy following infertility." The Australian & New Zealand journal of obstetrics & gynaecology, vol. 32, no. 3, 1992, pp. 249-251.
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Post Graduate Institute of Medical Education and Research009nfym65
Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education, and Research, Chandigarh, India.
Pregnancies of 112 patients who had conceived after a history of a minimum of 2 years of infertility were compared to an equal number of matching controls without prior infertility to find out any risk of increased pregnancy complications. These patients were at a significantly higher risk of developing first trimester bleeding, antepartum haemorrhage and intrauterine fetal death. Also there were higher rates of preterm delivery and Caesarean section. The patients in the study group had a significantly higher number of stillborn babies. The incidence of other complications such as ectopic pregnancy, multiple pregnancy, and medical complications was also higher in these patients but the difference was not statistically significant.
Pregnancy following a period of infertility was considered to be an increased risk for the fetus. During a period of 3 years (1983-85), 748 couples were seen at this infertility clinic; 515 women (68.9%) conceived, and were followed up and studied prospectively. Fifteen of these women moved out of the area. We analysed the results of pregnancies for the remaining 500, (Group 1) and compared them with the outcome for the total obstetric population (Group 2) during the same period. Mean age at conception in the infertility group (Group 1) was 31.8 (+/- 2.7, 2 SD) years, as compared with 23.7 (+/- 2.9, 2 SD) in the total hospital obstetric population (Group 2) (p less than 0.05). The incidences of spontaneous abortion for the two groups (8 and 6.2%) did not differ (p greater than 0.05). However, the incidence of ectopic pregnancy was higher (3.0%) in Group 1 than in Group 2 (1.5%) (p less than 0.01). The incidence of pre-existing hypertensive vascular disease (7.7%) complicating pregnancy and multiple pregnancy (4.1%) was significantly higher in Group 1 than in Group 2 (1.5% and 1.4% respectively), (p less than 0.01). The incidences of induction of labor (29.5%) and elective operative delivery (10.6%) were higher in Group 1 (p less than 0.01). The incidences of infants with birth weight below the tenth centile (12.9%), of fetal distress in labor (14.6%) and a low Apgar score (0-5) (9.5%), were higher in Group 1, but there was no difference in the perinatal mortality rate between the two groups.(ABSTRACT TRUNCATED AT 250 WORDS)
Kathpalia SK et al., 2016·Medical journal, Armed Forces India·Free full text on PubMed Central
Many infertile couples need treatment in different forms including Assisted Reproductive Techniques. In Vitro Fertilization and Embryo Transfer is the most advanced method of infertility treatment. Management of these pregnancies is difficult as the couples and treating doctors have undue concern and apprehension and worry about outcome of such pregnancies. This study was undertaken to find out the complications and mode of delivery and if there is a need to manage them at tertiary care centers. 130 cases were included in the study after pregnancy was confirmed in this prospective study. These cases were followed throughout pregnancy and labour. Pregnancy, labour, and neonatal complications were noted. Incidence of primary infertility was more common. Mean age of patient was more. All the cases were provided standard routine antenatal care. Multiple pregnancies and preterm labour were more frequent in the study group. A large number of cases delivered vaginally. A large number of pregnancies terminated in vaginal delivery, thereby indicating that these pregnancies though high risk can have vaginal delivery. They can be managed at any hospital once clinical pregnancy is confirmed.
We studied 500 women who conceived after investigation and treatment for different infertility problems and compared the outcome of the 5 infertility groups (Group 1 to 5), the ovulatory dysfunction (Group 1), male infertility (Group 2), A.I.D. (Group 3), tubal surgery and IVF (Group 4) and no treatment (Group 5) with the outcome in the hospital group during a period of 3 years. The incidence of abortion in Group 3 is significantly higher (13.8%), the incidence of ectopic pregnancy is significantly higher in Group 4 (21.7%) as compared with the incidence in the hospital group (P less than 0.01). The rate of pre-existing hypertension and gestational diabetes is significantly higher in all the 5 infertility groups as compared with the incidence in the hospital group (P less than 0.05). The incidence of preterm labor in general is less in the infertility group as compared with the incidence in the hospital group (P greater than 0.05). The incidence of older women, multiple pregnancy, induction of labor, operative deliveries, fetal distress, low Apgar score, babies with birth weight below the tenth centile were higher in the infertility groups (P less than 0.05). But the perinatal mortality or major or minor fetal anomalies were not significantly different in the infertility groups as compared with the rate in the hospital groups (P greater than 0.05).
Källén B, 2008·Best practice & research. Clinical obstetrics & gynaecology
Pregnancies following in-vitro fertilization (IVF) are known to be at increased risk of a number of pregnancy- and delivery-related complications when compared with non-IVF pregnancies. Most of these complications seem to be due to underlying fertility problems. Ovarian stimulation carries a marked risk for two serious conditions - ovarian torsion and ovarian hyperstimulation syndrome - both of which are relatively rare. Although some common pregnancy complications show an up to five times increased risk over non-IVF pregnancies, the absolute frequencies are still low for most of these conditions. However, an increased risk of placenta praevia might be to some extent due to the IVF procedure. No long-terms effects on cancer risk or mortality can be linked to the IVF procedure, although follow-up time is still relatively short.
Birth and Delivery › Birth Outcomes › Maternal Morbidity · Pregnancy › Pregnancy Complications › Premature Rupture of Membranes
PMID 1445139 1445139 DOI 10.1111/j.1479-828x.1992.tb01959.x 10.1111/j.1479-828x.1992.tb01959.x Bhalla et al. 1992, Bhalla 1992
Cite this article
Bhalla, A. K., Sarala, G., & Dhaliwal, L. (1992). Pregnancy following infertility. The Australian & New Zealand journal of obstetrics & gynaecology, 32(3), 249-251. https://doi.org/10.1111/j.1479-828x.1992.tb01959.x
Bhalla AK, Sarala G, Dhaliwal L. Pregnancy following infertility. Aust N Z J Obstet Gynaecol. 1992;32(3):249-251. doi:10.1111/j.1479-828x.1992.tb01959.x
Bhalla, ashish K., et al. "Pregnancy following infertility." The Australian & New Zealand journal of obstetrics & gynaecology, vol. 32, no. 3, 1992, pp. 249-251.
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