Autoimmune/Thrombophilic Disorders (as RPL Causes)

By RRM Academy Reviewed by Dr. Naomi Whittaker, MD, Board-Certified OBGYN, MIGS, NFPMC, FCI Updated May 7, 2026

Beyond APS, RRM evaluates for inherited thrombophilias (Factor V Leiden, prothrombin mutation, protein C/S deficiency), natural killer (NK) cell dysregulation, and systemic autoimmune conditions (antithyroid antibodies, antinuclear antibodies) in women with RPL. Assessment guides individualized medical therapy. See Clotting Disorder / Thrombophilia for a full breakdown of inherited vs acquired subtypes, risk stratification, and treatment approach.³⁷

This content is for educational purposes only and does not constitute medical advice. Consult an RRM clinician or healthcare provider for guidance specific to your situation.