Oxidative medicine and cellular longevity, 2021, 6668365, 2021
Abstract
Oxidative stress has been recognized as one of the causal mediators of female infertility by affecting the oocyte quality and early embryo development. Improving oxidative stress is essential for reproductive health. Melatonin, a self-secreted antioxidant, has a wide range of effects by improving mitochondrial function and reducing the damage of reactive oxygen species (ROS). This minireview illustrates the applications of melatonin in reproduction from four aspects: physiological ovarian aging, vitrification freezing, in vitro maturation (IVM), and oxidative stress homeostasis imbalance associated with polycystic ovary syndrome (PCOS), emphasising the role of melatonin in improving the quality of oocytes in assisted reproduction and other adverse conditions.
Topics
PMID 34367465 34367465 DOI 10.1155/2021/6668365 10.1155/2021/6668365 Jiang et al. 2021, Jiang 2021
Cite this article
Jiang, Y., Shi, H., Liu, Y., Zhao, S., & Zhao, H. (2021). Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress.. Oxidative medicine and cellular longevity, 2021, 6668365. https://doi.org/10.1155/2021/6668365
Jiang Y, Shi H, Liu Y, Zhao S, Zhao H. Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress.. Oxidative medicine and cellular longevity. 2021;2021:6668365. doi:10.1155/2021/6668365
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