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Cervical dilatation and prematurity revisited

Leveno KJ et al., 1986 Obstetrics and Gynecology

Cervical examination between 26 and 30 weeks' gestation is described as a method for identifying women at risk for delivery before 34 weeks. Blinded cervical examinations were performed in 185 consecu...

Pregnancy > Preterm Birth > Risk PredictionPregnancy > Prenatal Screening > Cervical AssessmentDiagnostics > Obstetric Evaluation > Cervical Examination

Natural family planning: an update

Derzko CM, 1986 Canadian Family Physician Medecin De Famille Canadien

Natural Family Planning (NFP) is defined by the World Health Organization (WHO) as "methods for planning or avoiding pregnancies by observation of the natural signs and symptoms of the fertile and inf...

Fertility Awareness > Methods > Symptothermal MethodFertility Awareness > Methods > Billings Ovulation MethodInfertility > Treatment > Fertility Awareness Applications

Endogenous sex hormones, prolactin, and breast cancer in premenopausal women

Meyer F et al., 1986 Journal of the National Cancer Institute

Forty-one women with breast cancer and 119 controls participated in a case-control study of the relation of endogenous sex hormones to breast carcinoma in premenopausal women. During the follicular ph...

Reproductive Endocrinology > Hormones > Progesterone and Cancer RiskGeneral OB/GYN > Breast Health > Hormonal Risk FactorsMenstrual Cycle > Luteal Phase > Hormone Levels and Disease

Mefenamic acid in the treatment of premenstrual syndrome

Mira M et al., 1986 Obstetrics and Gynecology

The use of mefenamic acid in the treatment of premenstrual syndrome (PMS) was investigated in 15 women over six menstrual cycles. A randomized, double-blind, cross-over, placebo-controlled design was ...

Menstrual Cycle > Premenstrual Syndrome > Pharmacological TreatmentResearch Methodology > Clinical Trials > Randomized Crossover DesignGeneral OB/GYN > Menstrual Disorders > PMS Management

Natural methods of family planning

Clubb E, 1986 Journal of the Royal Society of Health

Natural methods of family planning make use of the naturally occurring signs and symptoms of the fertile and infertile phases of the menstrual cycle. Recognizable signs and symptoms occur cyclically, ...

Fertility Awareness > Methods > Symptothermal MethodFertility Awareness > Methods > Billings Ovulation MethodBody Literacy > Cervical Mucus > Mucus Patterns and Fertility

Detection of preterm labor by ambulatory monitoring of uterine activity for the management of oral tocolysis

Katz M et al., 1986 American Journal of Obstetrics and Gynecology

A study to evaluate whether ambulatory tocodynamometry at home could enhance the management of oral tocolysis was performed. On discharge from the hospital, after completing parenteral tocolysis, 60 p...

Pregnancy > Preterm Birth > Monitoring and PreventionPregnancy > Preterm Birth > Tocolysis ManagementDiagnostics > Monitoring Devices > Ambulatory Tocodynamometry

Sperm migration through human cervical mucus in women with copper IUD's

Robert JA et al., 1986 Advances in contraceptive delivery systems : CDS

Human cervical mucus from women using Lippes Loop and T-Cu-200 IUDs was used to study sperm migration in vitro using flat capillary tubes. Cervical mucus from women bearing no IUD was used as the cont...

Contraception/Comparison > Intrauterine Devices > Mechanism of ActionAndrology > Sperm Function > Sperm Migration and Cervical MucusContraception/Comparison > Intrauterine Devices > Copper IUD Effects

The risks of the natural family planning methods

Zufferey MM, 1986 Therapeutische Umschau. Revue Therapeutique

Risks of 5 natural family planning (NFP) methods are compared. The main risk of these methods is the risk of pregnancy stemming from method failure, errors in instruction, error in application of the ...

Fertility Awareness > Methods > Comparative EffectivenessFertility Awareness > Methods > Risks and LimitationsFertility Awareness > Methods > Basal Body Temperature

Correlation between the zona-free hamster egg sperm penetration assay and human in vitro fertilization

Margalioth EJ et al., 1986 Fertility and Sterility

The association between in vitro fertilization (IVF) and the zona-free hamster egg sperm penetration assay (SPA) was studied in 134 couples. The indications for IVF were tubal disease in 82 couples, u...

Andrology > Sperm Function > Sperm Penetration AssayInfertility > Diagnostics > Male Factor AssessmentInfertility > Treatment > In Vitro Fertilization Screening

The better prognosis in secondary infertility is associated with a higher proportion of ovulation disorders

Collins JA et al., 1986 Fertility and Sterility

To determine the reason for the higher pregnancy rate in couples with secondary infertility, the authors compared 237 infertile couples who had a previous pregnancy in the current partnership (seconda...

Infertility > Prognosis > Secondary vs Primary InfertilityInfertility > Etiology > Ovulation DisordersReproductive Endocrinology > Ovulatory Dysfunction > Infertility Outcomes

The significance of luteal phase deficiency on fertility: a diagnostic and therapeutic approach

Balasch J et al., 1986 Human Reproduction (Oxford, England)

Luteal phase deficiency, diagnosed by endometrial biopsy, was found in 1 out of 25 control fertile women and in 46 out of 355 infertile patients, a difference that was not significant. It was also fou...

Infertility > Luteal Phase Deficiency > Diagnosis and TreatmentReproductive Endocrinology > Luteal Phase Defect > Endometrial BiopsyPregnancy > Recurrent Pregnancy Loss > Luteal Phase Support

The risk of fetal anomalies as a result of progesterone therapy during pregnancy

Check JH et al., 1986 Fertility and Sterility

The incidence of congenital anomalies in infants born to 382 women treated with P was noted. Only five anomalies occurred in the infants born to women who had taken P. This study supports the data of ...

Reproductive Endocrinology > Progesterone Therapy > Safety in PregnancyPregnancy > Medications in Pregnancy > Fetal Anomaly RiskInfertility > Luteal Phase Support > Progesterone Safety

A double-blind placebo-controlled trial of progesterone vaginal suppositories in the treatment of premenstrual syndrome

Maddocks S et al., 1986 American Journal of Obstetrics and Gynecology

Rigorous criteria were used to select women with severe premenstrual syndrome for inclusion in an 8-month double-blind placebo-controlled clinical trial of progesterone vaginal suppositories. Followin...

Reproductive Endocrinology > Progesterone Therapy > Premenstrual SyndromeMenstrual Cycle > Premenstrual Syndrome > Hormonal TreatmentResearch Methodology > Randomized Controlled Trials > Crossover Design

Ultrasound differentiation of the competent from the incompetent cervix: prevention of preterm delivery

Michaels WH et al., 1986 American Journal of Obstetrics and Gynecology

To evaluate the feasibility of the use of serial ultrasound measurements of cervical length, membrane protrusion, and dilatation to discriminate between the competent and the incompetent cervix, 107 a...

Pregnancy > Preterm Birth > Cervical Incompetence DiagnosisDiagnostics > Ultrasound > Cervical Length MeasurementPregnancy > Cervical Insufficiency > Prevention of Preterm Delivery

The effects of oral administration of progesterone for premature labor

Erny R et al., 1986 American Journal of Obstetrics and Gynecology

The potential tocolytic effect of natural progesterone administration on premature labor was investigated in a double-blind study. An oral progesterone formulation was used because its ability to incr...

Pregnancy > Preterm Birth > Progesterone TocolysisReproductive Endocrinology > Progesterone Therapy > Preterm Labor PreventionResearch Methodology > Randomized Controlled Trials > Double-Blind Placebo

Correlation of vaginal hormonal cytograms with cervical mucus symptoms as observed by women using the ovulation method of natural family planning

Taylor RS et al., 1986 The Journal of Reproductive Medicine

The first study was done in which vaginal hormonal cytograms were correlated with cervical mucus symptoms as charted by women using the ovulation method of natural family planning. Daily vaginal smear...

Fertility Awareness > Ovulation Method > Biomarker ValidationDiagnostics > Vaginal Cytology > Hormonal CytogramMenstrual Cycle > Ovulation Detection > Cervical Mucus Correlation

Ovulation induction with low doses of clomiphene citrate

Dodge ST et al., 1986 Obstetrics and Gynecology

Ovulation was induced with one-quarter tablet (12.5 mg) of clomiphene citrate given for five days to three oligoovulatory patients who had consistently formed functional ovarian cysts when given 50 an...

Infertility > Ovulation Induction > Low-Dose Clomiphene CitratePCOS > Treatment > Clomiphene Citrate ProtocolsReproductive Endocrinology > Ovulation Induction > Dose Optimization

Precocious cervical ripening and preterm labor

Papiernik E et al., 1986 Obstetrics and Gynecology

A group of 8303 women was studied to determine the timing of cervical ripening. It was confirmed that these signs of cervical change can be observed several weeks before preterm births. The precocious...

Pregnancy > Preterm Birth > Cervical Ripening PredictionDiagnostics > Clinical Examination > Cervical AssessmentGeneral OB/GYN > Preterm Labor > Screening and Prevention

Professional Program Development in Natural Family Planning

Hilgers TW, 1986 The Linacre Quarterly

There is no information available about the effect of iron in formula on the development of gastrointestinal humoral immune response in early human infancy. We compared standard Enfamil to iron-fortif...

NaProTECHNOLOGY > Education > Professional TrainingFertility Awareness > Program Development > NFP EducationRRM Methods > Clinical Programs > Service Development

Pitfalls in sonographic imaging of the incompetent uterine cervix

Confino E et al., 1986 Acta Obstetricia Et Gynecologica Scandinavica

Artifacts interfering with sonographic imaging of the uterine cervix in pregnancy are described. Increasing the amount of fluid in the urinary bladder closes the cervix and alters the configuration of...

General OB/GYN > Cervical Incompetence > Diagnostic ImagingDiagnostics > Ultrasound > Cervical AssessmentPregnancy > Complications > Cervical Insufficiency

Conditioning exercise decreases premenstrual symptoms. A prospective controlled three month trial

Prior JC et al., 1986 European Journal of Applied Physiology and Occupational Physiology

Conditioning exercise decreased premenstrual symptoms during 3 months of a prospective controlled training study. Eight women with normal ovulatory menstrual cycles began a running exercise training p...

Menstrual Cycle > Premenstrual Syndrome > Exercise InterventionMenstrual Cycle > Premenstrual Syndrome > Non-Pharmacological TreatmentReproductive Endocrinology > Ovulatory Function > Exercise Effects

Association of endometriosis and spontaneous abortion: effect of control group selection

Metzger DA et al., 1986 Fertility and Sterility

Endometriosis has been associated with an increased incidence of spontaneous abortion, compared with the abortion rate of the general population. To assess whether a separate control group would affec...

Endometriosis > Outcomes > Spontaneous AbortionEndometriosis > Treatment > Conservative SurgeryResearch Methodology > Study Design > Control Group Selection

Embryotoxicity of a single dose of medroxyprogesterone acetate (MPA) and maternal serum MPA concentrations in cynomolgus monkey (Macaca fascicularis)

Prahalada S et al., 1985 Teratology

A single dose of MPA (Depo-Provera; Upjohn Co., Kalamazoo, Michigan) was administered intramuscularly to 12 time-mated pregnant cynomolgus monkeys on day 27 (+/- 2) of gestation at 25 mg/kg or at 100 ...

Reproductive Endocrinology > Progestogens > Fetal ToxicityPregnancy > Teratology > Hormonal ExposureContraception/Comparison > Injectable Contraceptives > Safety Concerns

Lactation and postpartum infertility: the use-effectiveness of natural family planning (NFP) after term pregnancy

Hatherley LI, 1985 Clinical Reproduction and Fertility

The use-effectiveness of natural methods of family planning in lactation is evaluated by comparing the incidence of unplanned pregnancies in a group of nursing mothers practising these methods with th...

Fertility Awareness > Postpartum > Lactational InfertilityPostpartum > Breastfeeding > Return of FertilityFertility Awareness > Effectiveness > NFP Use-Effectiveness

Neuropeptide levels in premenstrual syndrome

Chuong CJ et al., 1985 Fertility and Sterility

To determine whether changes in circulating levels of neuropeptides are associated with symptoms of premenstrual syndrome (PMS), 20 women with the diagnosis of PMS and 20 asymptomatic subjects were st...

Menstrual Cycle > Premenstrual Syndrome > Neuroendocrine FactorsReproductive Endocrinology > Neuropeptides > Beta-EndorphinMenstrual Cycle > Premenstrual Syndrome > Pathophysiology

The association of subclinical infection with preterm labor: the role of C-reactive protein

Potkul RK et al., 1985 American Journal of Obstetrics and Gynecology

The role of subclinical intrauterine infection in preterm labor was evaluated prospectively in 40 patients and appropriate control subjects. The 24 preterm labor patients (60%) with a negative C-react...

Pregnancy > Preterm Labor > Subclinical InfectionPregnancy > Preterm Labor > Tocolysis ResponseDiagnostics > Biomarkers > C-Reactive Protein in Pregnancy

Embryotoxicity and maternal serum concentrations of medroxyprogesterone acetate (MPA) in baboons (Papio cynocephalus)

Prahalada S et al., 1985 Contraception

A single dose of MPA (Depo-Provera; Upjohn Co.; USA) was administered intramuscularly on day 27 (+/- 2) of gestation to three dosage groups of pregnant baboons. The dosage expressed as mg/kg correspon...

Contraception/Comparison > Hormonal Contraceptives > Depo-Provera SafetyReproductive Endocrinology > Progesterone > Synthetic Progestin EffectsPregnancy > Teratogenicity > Progestin Exposure

Evidence for an increased risk of Crohn's disease in oral contraceptive users

Lesko SM et al., 1985 Gastroenterology

The risk of Crohn's disease in relation to oral contraceptive use was evaluated in a hospital-based, case-control study of 57 women with Crohn's disease and 2189 controls with other conditions. The re...

Contraception/Comparison > Oral Contraceptives > Adverse EffectsGeneral OB/GYN > Autoimmune Disease > Oral Contraceptive AssociationResearch Methodology > Case-Control Studies > Contraceptive Side Effects

The effects of spironolactone on adrenal steroidogenesis in hirsute women

Serafini P et al., 1985 Fertility and Sterility

The effect of spironolactone on adrenal androgen and cortisol production was studied in six hirsute women. Hirsute women were evaluated before and 1 month after receiving 200 mg of spironolactone dail...

Reproductive Endocrinology > Androgens > Adrenal SteroidogenesisPCOS > Hirsutism > Anti-Androgen TherapyReproductive Endocrinology > Adrenal Function > Enzyme Inhibition

The endometrial biopsy for diagnosis of luteal phase deficiency

Balasch J et al., 1985 Fertility and Sterility

We studied endometrial luteal phase in specimens from 660 biopsies done in 300 patients from our infertility clinic. A minimum of two (240 women) or three (60 women) endometrial biopsy specimens from ...

Diagnostics > Endometrial Biopsy > Luteal Phase AssessmentInfertility > Luteal Phase Deficiency > Diagnostic MethodsReproductive Endocrinology > Luteal Phase > Endometrial Dating

Bioavailability of oral micronized progesterone

Maxson WS et al., 1985 Fertility and Sterility

Progesterone (P) has not been administered orally because of reportedly poor bioavailability and a rapid clearance rate. Unfortunately, the synthetic derivatives, although orally active, have a number...

Reproductive Endocrinology > Progesterone > Oral Micronized ProgesteronePerimenopause/Menopause > Hormone Therapy > Progesterone ReplacementDiagnostics > Pharmacokinetics > Progesterone Bioavailability

Effect of peritoneal fluid on in vitro cleavage of 2-cell mouse embryos: possible role in infertility associated with endometriosis

Morcos RN et al., 1985 Fertility and Sterility

The purpose of this study was to evaluate the effect of peritoneal fluid (PF) on in vitro cleavage of 2-cell mouse embryos. PF was aspirated from the posterior cul-de-sac at laparoscopy and centrifuge...

Endometriosis > Pathophysiology > Peritoneal Fluid EffectsInfertility > Endometriosis-Associated > Embryotoxicity MechanismsResearch Methodology > In Vitro Studies > Embryo Culture

Failure of intraperitoneal adjuncts to improve the outcome of pelvic operations in young women

Jansen RP, 1985 American Journal of Obstetrics and Gynecology

An examination was made of the possibility that 100 to 200 ml of intraperitoneal 32% dextran 70 and/or 0.5% hydrocortisone sodium succinate (randomized independently with similar volumes of Ringer's l...

Surgery > Adhesion Prevention > Intraperitoneal AdjunctsEndometriosis > Surgical Treatment > Adhesion OutcomesInfertility > Tubal Surgery > Postoperative Adhesion Prevention

Sensory neuropathy with low-dose pyridoxine

Parry GJ et al., 1985 Neurology

We describe 16 patients with neuropathy associated with pyridoxine abuse. The clinical picture of a pure sensory central-peripheral distal axonopathy was consistent. Pyridoxine dose was 0.2 to 5 g/d, ...

General OB/GYN > Nutritional Supplements > Vitamin B6 ToxicityDiagnostics > Neuropathy > Pyridoxine-Induced Sensory Neuropathy

Systemic lupus erythematosus and reproductive function: a case-control study

Grimes DA et al., 1985 American Journal of Obstetrics and Gynecology

Systemic lupus erythematosus characteristically afflicts women of reproductive age, yet the explanation for this feature is unknown. This hospital-based, case-control study of 109 incident cases of sy...

General OB/GYN > Autoimmune Disease > Systemic Lupus ErythematosusEndometriosis > Comorbidities > Autoimmune Disease AssociationResearch Methodology > Case-Control Studies > Reproductive Risk Factors

Natural family planning after pregnancy. A problem for women with previously irregular menstrual cycles

Hatherley LI, 1985 Clinical reproduction and fertility

A prospective six-year study (1975-1980) of 273 patients, monitored in the use of natural family planning (NFP), has shown that those with previously irregular menstrual cycles are disadvantaged in th...

Fertility Awareness > Ovulation Method > Postpartum ApplicationPostpartum > Return of Fertility > Irregular CyclesBody Literacy > Menstrual Cycle Monitoring > Postpartum Charting

Treatment of habitual abortion with human chorionic gonadotropin: results of open and placebo-controlled studies

Harrison RF, 1985 European Journal of Obstetrics, Gynecology, and Reproductive Biology

Human chorionic gonadotropin was administered intramuscularly in an open study of 32 women whose last three pregnancies had ended in spontaneous abortion. An initial dosage of 10 000 iu on earliest di...

Infertility > Recurrent Pregnancy Loss > hCG TreatmentPregnancy > Miscarriage Prevention > Hormonal SupportResearch Methodology > Randomized Controlled Trials > Placebo-Controlled Studies

The repetition of spontaneous preterm labour

Carr-Hill RA et al., 1985 British Journal of Obstetrics and Gynaecology

The likelihood of repetition of preterm birth after spontaneous onset of labour has been studied in 6572 reproductive careers after excluding stillbirths, multiple births, all careers in which any lab...

Pregnancy > Preterm Birth > Recurrence RiskPregnancy > Preterm Labor > EpidemiologyResearch Methodology > Retrospective Cohort Studies > Reproductive Outcomes

Protective effects of progesterone and tamoxifen in estrogen-induced mammary carcinogenesis in ovariectomized W/Fu rats

Inoh A et al., 1985 Japanese Journal of Cancer Research : Gann

The protective effect of progesterone or tamoxifen, an antiestrogenic agent, was investigated in estrogen-induced mammary carcinogenesis. Multiple mammary tumors (MT) of tubular or medullary carcinoma...

Reproductive Endocrinology > Progesterone > Cancer Protective EffectsReproductive Endocrinology > Estrogen > Mammary CarcinogenesisResearch Methodology > Animal Studies > Rat Models

Initial evaluation of an ambulatory system for home monitoring and transmission of uterine activity data

Katz M et al., 1985 Obstetrics and Gynecology

A system capable of ambulatory home monitoring of uterine activity and data transmission was evaluated in a group of pregnant patients. The evaluation focused on three questions: 1) Is the information...

Pregnancy > Preterm Labor > Home MonitoringDiagnostics > Uterine Activity Monitoring > Ambulatory SystemsPregnancy > High-Risk Pregnancy > Surveillance Technology