Fertility Awareness · Biomarkers

Cervical mucus and identification of the fertile phase of the menstrual cycle

Flynn AM, Lynch SS

Published August 1976 British Journal of Obstetrics and Gynaecology, 83(8), 656-659
DOI 10.1111/j.1471-0528.1976.tb00906.x PMID 952797

RRM Academy Synopsis

Nine fertile women predicted ovulation by grading their cervical mucus

Nine healthy women who graded their own cervical mucus identified the fertile phase of their cycle, a 1976 Birmingham study of 29 cycles found. Any mucus appeared on average 5.2 days before the LH peak. The study took the LH peak as the day of ovulation.

Key Findings

  • Nine healthy women, aged 26 to 44, were followed through 29 menstrual cycles, and an LH peak was observed in all 29 cycles.
  • Basal body temperature showed a biphasic pattern in 26 of the 29 cycles; the other 3 cycles had missing or insufficient temperature readings.
  • Any mucus first appeared on average 5.2 days before the LH peak.
  • In 8 of the 29 cycles, in five women, the fertile mucus phase before ovulation lasted only two days.
  • The women identified cervical mucus in the 29 cycles, and grading became easier with continued observation.

Interpretation

The study is a small observational series of nine healthy volunteers, each with three to six children. Blood samples dated ovulation by the LH peak, with no ultrasound confirmation. No pregnancies occurred, so pregnancy outcomes were not tested. The women were fertile. The authors suggest the method could help infertile women recognize ovulation, but infertile women were not studied. Seminal fluid after intercourse caused some confusion in early cycles. One woman had a vaginal infection in the second half of a cycle.

RRM Context

Restorative reproductive medicine reads the cycle as information about how the reproductive system is working. The women here recorded cervical mucus alongside basal body temperature. Symptothermal methods pair these two signs to mark the fertile window. Blood sampling served as the reference in this study. Daily observation by the woman needs no blood draw. Charting gives a couple a shared record of the fertile window.

Abstract

Nine healthy fertile women were studied during 29 menstrual cycles. A cervical mucus grading system, assessed by the patient and used in conjunction with basal body temperature, was correlated with plasma levels of luteinizing hormone (LH), oestradiol and plasma progesterone. The results show that a patient can be taught to predict the time of ovulation by observing the changes in the cervical mucus.

Topics

By this author

Related research

Fertility Awareness › Biomarkers › Cervical Mucus · Menstrual Cycle › Cycle Biomarkers › Cervical Mucus · Reproductive Endocrinology › Ovulation Physiology › Follicular Development
Anna M. Flynn
A Flynn
PMID 952797 952797 DOI 10.1111/j.1471-0528.1976.tb00906.x 10.1111/j.1471-0528.1976.tb00906.x Flynn et al. 1976, Flynn 1976