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By this author
Bowel Invisible Microscopic Endometriosis: Leave It Alone
Redwine DB et al., 2018 · Journal of minimally invasive gynecology
Dissecting and temporarily resuspending the adherent ovary
Redwine DB, 2006 · Fertility and sterility
Variations in tubal configuration in endometriosis?
Redwine DB, 2006 · Fertility and sterility
Chronic pelvic pain associated with autoimmunity and systemic and peritoneal inflammation and treatment with immune modification
Thomson JC et al., 2005 · The Journal of reproductive medicine
To determine the prevalence of chronic inflammation of the pelvic peritoneum, systemic inflammation and autoimmunity in chronic pelvic pain and to explore the significance of these findings and assess the response to treatment with immune modification. Prospective, observational clinical studies from 2 centers were performed on 3,238 women presenting with pelvic pain to determine the prevalence of chronic inflammation by biopsy when endometriosis was absent. A second study included 40 women with chronic pelvic pain not resulting from endometriosis; immunologic investigations were carried out and therapy instituted. Chronic inflammation of the peritoneum, while not evident in the absence of pelvic pain, was present in 15.7% of women with chronic pelvic pain. In the second group, 10% had histologic evidence of chronic inflammation, 55% demonstrated evidence of systemic inflammation, and 37.5% were found to have autoimmune disorders. Chronic inflammation of the vagina was found in 42.5% and polycystic ovary syndrome in 22% of those with systemic inflammation. Twelve of the 40 were subsequently treated, with considerable success, with immune-modifying drugs, hydroxychloroquine and methotrexate. Chronic pelvic pain is frequently associated with systemic inflammation, including autoimmune diseases. Peritoneal chronic inflammation is sometimes also associated. It is often successfully treated with immune-modifying drugs.
Related research
Epidemiology of complications associated with gynecological laparoscopy procedures in Ukraine: results a multicenter study
Salmanov AG et al., 2024 · Wiadomosci lekarskie (Warsaw, Poland : 1960)
To estimate the frequency of complications during laparoscopic gynecologic surgery for benign diseases in women and identify associated risk factors in Ukraine. Materials and A multicenter, prospective cohort study was performed in gynecological departments from 10 regional hospitals of Ukraine between January 1, 2020, to December 31, 2022. The study included gynecologic laparoscopies for benign diseases in women performed at these hospitals. To identify risk factors and variables associated with complications, crude and adjusted odds ratios were calculated with unconditional logistic regression. Surveillance was performed during 30 days after gynecological laparoscopy procedures. A total of 14,440 laparoscopic surgeries were performed, 2,340 (16.2%) complications cases were observed. Of all complication's cases, 74.9% were detected after hospital discharge. The overall frequency of major complications was 5.04%, and that of minor complications was 11.2%. The most frequently reported complications types were serious bleeding complications (20.6%), intestinal perforation (17.9%), mild anemia (16.7%), severe anemia (transfusion) (16.1%), failed laparoscopy (9.3%), minor bleeding complications (8.3%), postoperative hematoma (6.7%), urinary tract infection (5.6%), and fever (5.0%). The level of technical difficulty and existence of prior abdominal surgery, and obesity were associated with a higher risk of complications associated with gynecological laparoscopy procedures. Results this study suggest a high frequency of complications associated laparoscopic gynecologic surgery in Ukraine. Greater technical difficulty and prior surgery were factors associated with a higher frequency of complications.