Effects of in vitro fertilization on low birth weight, preterm delivery, and multiple birth

Suzanne C. Tough; Calvin A. Greene; Larry W. Svenson; Jaques Belik

doi:10.1067/mpd.2000.105132

Assisted Reproduction Safety and Risks

Effects of in vitro fertilization on low birth weight, preterm delivery, and multiple birth

Tough SC, Greene CA, Svenson LW, Belik J

Published May 10, 2000 The Journal of Pediatrics, 136(5), 618-622

DOI 10.1067/mpd.2000.105132 PMID 10802493

Abstract

Purpose

To quantify the contribution of in vitro fertilization (IVF) on changes in the rates of low birth weight (LBW), preterm delivery, very low birth weight, and multiple births during the past 3 years.

Methods

Data on IVF pregnancies from 1994 to 1996 within Alberta were reviewed. Population data were obtained from the Provincial notice of a live or stillbirth.

Results

The IVF component of increased LBW rate in the province was 17.8% for infants <2500 g and 43.5% for those born <1500 g. IVF accounted for 10.5% of the provincial rate increase in deliveries <37 weeks' gestation and 66.2% of those <30 weeks' gestation. IVF accounted for 21.4% of the twins and all of the sets of triplets in the province.

Conclusion

During a 3-year period IVF has affected the incidence of LBW, preterm delivery, and multiple birth. IVF is a substantial contributor to changes in very low birth weight and delivery before 30 weeks, which is partly related to multiple births.

Topics

Assisted Reproduction › Safety and Risks › Neonatal and Birth Outcomes · Pregnancy › Neonatal Outcomes › Birth Weight · Birth and Delivery › Birth Outcomes › Maternal Morbidity

Suzanne C. Tough, Calvin A. Greene, Larry W. Svenson, Jaques Belik

S Tough, C Greene, Lawrence Svenson, Laurence Svenson, L Svenson, J Belik

PMID 10802493 10802493 DOI 10.1067/mpd.2000.105132 10.1067/mpd.2000.105132 Tough et al. 2000, Tough 2000

Keywords

Alberta/epidemiology, Female, Fertilization in Vitro, Humans, Incidence, Infant, Low Birth Weight, Infant, Newborn, Infant, Very Low Birth Weight, Obstetric Labor, Premature/epidemiology, Pregnancy, Pregnancy, Multiple

Effects of in vitro fertilization on low birth weight, preterm delivery, and multiple birth

Abstract

Topics

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Keywords