Assisted Reproduction · Add-Ons and Adjuncts

Enhancement of Ovarian Reserve and Oocyte Quality After Platelet-Rich Plasma Instillation in a Woman With Diminished Anti-Müllerian Hormone

Shrivastava J, More A, Shrivastava V, Choudhary N, Shrivastava D

Published February 2, 2024 Cureus
DOI 10.7759/cureus.53474 PMID 38440028 PMC PMC10910621

Abstract

Platelet-rich plasma (PRP) is a concentrated platelet preparation known for its regenerative properties due to the various growth factors it contains. Its application in the medical field, including dentistry, gynecology, and plastic surgery, has surged. In obstetrics and gynecology, PRP has shown promise in improving low libido, vaginal rejuvenation, ovarian reserve, and endometrial receptivity. This study presents a 29-year-old woman experiencing primary infertility attributed to low levels of anti-Müllerian hormone alongside the presence of asthenozoospermia in her husband's semen. After failed intrauterine insemination as well as in vitro fertilization (IVF), attempts at laparoscopic PRP treatment were administered before the second IVF cycle to enhance ovarian reserve and quality. The PRP treatment led to an increased follicle count, improved oocyte quality, and a successful pregnancy outcome in the second IVF cycle. PRP treatment promises to be effective in fertility treatments, potentially increasing ovarian reserve, improving oocyte quality, and enhancing successful pregnancy outcomes. This case report highlights its beneficial impact on a couple facing primary infertility, providing hope for patients with similar reproductive challenges.

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Assisted Reproduction › Add-Ons and Adjuncts › Adjunct Evidence Base · Therapeutics › Emerging Therapies › Platelet-Rich Plasma · Reproductive Endocrinology › Ovarian Hormones › Estrogen
Jarul Shrivastava, Akash More, Virul Shrivastava, Namrata Choudhary, Deepti Shrivastava
J Shrivastava, A More, V Shrivastava, N Choudhary, D Shrivastava
PMID 38440028 38440028 DOI 10.7759/cureus.53474 10.7759/cureus.53474 Shrivastava et al. 2024, Shrivastava 2024