Reproductive Surgery Adhesion Prevention

Laparoscopic implant of Gore-Tex surgical membrane

Crain J, Curole D, Hill G, Hurst B, Metzger D, Murphy A, Perloe M, Reich H, Rowe G, Sanfillipo J

Published August 1995 The Journal of the American Association of Gynecologic Laparoscopists, 2(4), 417-420
DOI 10.1016/s1074-3804(05)80063-5 PMID 9050595

Abstract

One of the major postoperative complications of reproductive surgery is the formation of adhesions. 1, 2 Over the past several decades a number of methods have been explored to solve this problem, g, 4 Recently there has been renewed interest in covering the damaged peritoneal surface with an absorbable or nonabsorbable barrier as a means of preventing adhesions after fertility-enhancing surgery. Currently, two barriers are commercially available for clinical use: Interceed Absorbable Adhesion Barrier (Ethicon, Somerville, NJ), which is composed of oxidized regenerated cellulose, and the Gore-Tex Surgical Membrane (W. L. Gore & Associates, Inc., Flagstaff, AZ), constructed of expanded polytetrafluoroethylene (e-PTFE). Interceed has been investigated both experimentally and clinically and has proved effective in some circumstances. 5,6 Studies also report on the laparoscopic application of Interceed in fertility-enhancement procedures.7, 8 Recent reports, however, have questioned the product's degree of effectiveness and raised concern about possible residual effects it may have on peritoneal tissue? 11 Gore-Tex Surgical Membrane has been indicated for use in peritoneal reconstruction since 1983, and experimental and clinical reports describe its effectiveness in preventing adhesion formation. 12-14 Interceed is an absorbable material that is phagocytized by macrophages within 1 month. Gore-Tex Surgical Membrane is nonabsorbable and is intended to be a permanent implant. Since all published reports on the clinical application of the Gore-Tex membrane discuss implantation by laparotomy, ~g, 14 the ease of use of this product in laparoscopic surgery is of particular interest. Moreover, because of its permanence, its long-term safety and effectiveness merit examination. A prospective, multicenter clinical study was undertaken to evaluate the ease of using Gore-Tex Surgical Membrane laparoscopically.

Read the guide

Topics

By this author

Related research

Reproductive Surgery › Adhesion Prevention › Barrier Agents
Harry Reich
H Reich
PMID 9050595 9050595 DOI 10.1016/s1074-3804(05)80063-5 10.1016/s1074-3804(05)80063-5 Crain et al. 1995, Crain 1995