Studies on the penetration of radioactive ions through human cervical mucus

Odeblad E, Westin B

Published May 1958 Acta Radiologica, 49(5), 382-388
DOI 10.3109/00016925809171005
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RRM Academy Synopsis

Sodium ions appear to move slowest through cervical mucus at ovulation

In a 1958 lab study of cervical mucus from apparently healthy women, radioactive sodium appeared to pass quickly after the period and slowly near ovulation. The authors call the work preliminary.

Key Findings

  • Mucus samples came from some apparently healthy women with regular ovarian cycles. Radioactive sodium was placed on top of each sample, and its spread downward was counted over time.
  • After the period, ions diffused through the cervical mucus rather quickly.
  • Near midcycle, when the secretion turned transparent and abundant and showed arborization (a fern-like crystal pattern), the diffusion coefficient appeared considerably suppressed.
  • The diffusion coefficient varied about tenfold across the cycle. Each measured value may be off by a factor of two or so, a smaller error than that change.
  • In the authors' words, diffusion proceeded slowest when the percentage of water in the mucus was highest.

Interpretation

The study is a bench experiment on mucus samples, and the paper gives no count of women. The authors describe their method as approximate and their approach as preliminary. The result suggests a cyclic change in how ions move through mucus in an unspecified number of women. The authors reason that slow movement at midcycle may reflect water held tightly to the mucus, and they tie it to higher viscosity. The paper reports no pregnancy or fertility outcome.

RRM Context

Cervical mucus changes through the cycle with the hormones acting on the cervical glands, a point the authors cite from earlier work. Fertility awareness-based methods build on that changing secretion. The Creighton Model and other mucus-observation methods teach women to chart it. This 1958 measurement adds one physical property of midcycle mucus.

Abstract not indexed.

By this author

Related research

DOI 10.3109/00016925809171005 10.3109/00016925809171005 Odeblad et al. 1958, Odeblad 1958