The effect of alpha-tocopherol on premenstrual symptomatology: a double-blind study

London RS; Sundaram GS; Murphy L; Goldstein PJ

doi:10.1080/07315724.1983.10719916

Menstrual Cycle · Premenstrual Disorders

The effect of alpha-tocopherol on premenstrual symptomatology: a double-blind study

London RS, Sundaram GS, Murphy L, Goldstein PJ

Journal of the American College of Nutrition, 2(2), 115-122, 1983

DOI 10.1080/07315724.1983.10719916 PMID 6350402

Abstract

In a double-blind, randomized dose-response study, 75 women with benign breast disease were administered a written questionnaire in which they scored the severity of premenstrual syndrome (PMS) symptoms before and after two months of treatment with placebo or alpha-tocopherol (150, 300, or 600 IU/day). Controlling for age and pretreatment scores, alpha-tocopherol had a significantly greater effect than placebo, improving three of the four classes of PMS symptoms. These findings suggest that vitamin E supplementation may be of value in women with severe PMS symptoms.

Topics

Menstrual Cycle Premenstrual Disorders Premenstrual Syndrome Treatment

Menstrual Cycle › Premenstrual Disorders › Premenstrual Syndrome Treatment

Laura Murphy

L Murphy

PMID 6350402 6350402 DOI 10.1080/07315724.1983.10719916 10.1080/07315724.1983.10719916 London et al. 1983, London 1983

Keywords

Adolescent, Adult, Clinical Trials As Topic, Dose-Response Relationship, Drug, Double-Blind Method, Female, Humans, Menstruation Disturbances/drug Therapy, Middle Aged, Premenstrual Syndrome/drug Therapy, Syndrome, Vitamin E/therapeutic Use, Vitamin E

The effect of alpha-tocopherol on premenstrual symptomatology: a double-blind study

Abstract

Topics

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