Utilization of Low-Dose Naltrexone for Burning Mouth Syndrome: A Case Report

Neuman DL; Chadwick AL

doi:10.1213/xaa.0000000000001475

Therapeutics · Emerging Therapies

Utilization of Low-Dose Naltrexone for Burning Mouth Syndrome: A Case Report

Neuman DL, Chadwick AL

Published May 2021 A&A Practice, 15(5), e01475

DOI 10.1213/xaa.0000000000001475 PMC PMC8311810

Abstract

Burning mouth syndrome is a chronic pain condition characterized by a burning sensation of the oropharynx. The pathophysiology of burning mouth syndrome includes peripheral and central sensitization. Treatment is generally aimed at symptom reduction. We describe a woman in her seventh decade with burning mouth syndrome that had been refractory to treatment for nearly a decade. Low-dose naltrexone has been reported to provide analgesia in central sensitization states and was successful in reducing pain severity in our patient. We conclude that low-dose naltrexone may be a therapeutic option for patients with burning mouth syndrome who are refractory to conventional therapies.

Topics

Therapeutics Emerging Therapies Low-Dose Naltrexone

Therapeutics › Emerging Therapies › Low-Dose Naltrexone

DOI 10.1213/xaa.0000000000001475 10.1213/xaa.0000000000001475 Neuman et al. 2021, Neuman 2021

Utilization of Low-Dose Naltrexone for Burning Mouth Syndrome: A Case Report

Abstract

Topics

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