Adenomyosis

By RRM Academy Reviewed by Dr. Naomi Whittaker, MD, Board-Certified OBGYN, MIGS, NFPMC, FCI Updated May 7, 2026

A condition in which endometrial-like glands and stroma are present within the myometrium (uterine muscle wall), causing the uterus to enlarge and the junctional zone (the inner myometrium) to thicken. Adenomyosis is associated with heavy, painful periods and impaired fertility. A meta-analysis found women with adenomyosis had a 28% decreased probability of clinical pregnancy via IVF/ICSI compared to women without it, and higher miscarriage rates (OR 2.17). RRM approaches include hormonal management, and in selected cases, surgical resection of focal lesions.⁴⁸⁴⁹⁵⁰

This content is for educational purposes only and does not constitute medical advice. Consult an RRM clinician or healthcare provider for guidance specific to your situation.