Reproductive Endocrinology · Ovarian Hormones

Changes in circulating hormone levels after ovarian wedge resection in patients with polycystic ovary syndrome

Szilágyi A, Rossmanith W, Csermely T, Csaba I

Archives of Gynecology and Obstetrics, 248(1), 31-35, 1990
DOI 10.1007/BF02389587 PMID 2124095

Abstract

Serum gonadotropin, prolactin, estradiol, sex hormone binding globulin (SHBG) and androgen levels were measured before, 5 days and 6 weeks following ovarian wedge resection in 9 patients with polycystic ovary syndrome. Elevated levels of LH, androstenedione, testosterone and dehydroepiandrosterone-sulphate (DHEA-S) were found before surgery. There was a marked decrease in androstenedione and DHEA-S levels 5 days following wedge resection, but a rebound effect could be observed 6 weeks later. Serum gonadotropin, prolactin, testosterone and SHBG concentrations were practically unaffected by surgery. At 6-12 months follow up patients showed regular, mainly ovulatory cycles, but pregnancy occurred only in two cases.

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Related research

Reproductive Endocrinology › Ovarian Hormones › Androgens · PMOS / PCOS › Surgical Treatment › Ovarian Wedge Resection · Menstrual Cycle › Cycle Disorders › Ovulatory Disturbances
PMID 2124095 2124095 DOI 10.1007/BF02389587 10.1007/BF02389587 Szilágyi et al. 1990, Szilágyi 1990