Uterine and Pelvic Conditions · Fibroids

Epidemiology of Uterine Fibroids: From Menarche to Menopause

Wise LA, Laughlin-Tommaso SK

Published March 2016 Clinical obstetrics and gynecology, 59(1), 2-24
DOI 10.1097/GRF.0000000000000164 PMID 26744813 PMC PMC4733579

Abstract

Uterine leiomyomata (UL) have a substantial impact on women's health, but relatively few studies have identified opportunities for primary prevention of these neoplasms. Most established risk factors are not modifiable, including premenopausal age, African ancestry, age at menarche, and childbearing history. The main challenge in studying UL is that a large proportion of tumors are asymptomatic. Herein, we review the epidemiology of UL from published studies to date. We highlight the advantages of ultrasound screening studies and the ways in which their innovative methods have helped clarify the etiology of disease. We conclude with a discussion of promising new hypotheses.

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Uterine and Pelvic Conditions › Fibroids › Fibroid Classification
Lauren A Wise, Shannon K Laughlin-Tommaso
L Wise, S Laughlin-Tommaso
PMID 26744813 26744813 DOI 10.1097/GRF.0000000000000164 10.1097/GRF.0000000000000164 Wise et al. 2016, Wise 2016