Inflammatory Markers in Dysmenorrhea and Therapeutic Options

Zofia Barcikowska; Elżbieta Rajkowska-Labon; Magdalena Emilia Grzybowska; Rita Hansdorfer-Korzon; Katarzyna Zorena

doi:10.3390/ijerph17041191

General Gynecology · Pelvic Pain

Inflammatory Markers in Dysmenorrhea and Therapeutic Options

Barcikowska Z, Rajkowska-Labon E, Grzybowska ME, Hansdorfer-Korzon R, Zorena K

Published February 13, 2020 International journal of environmental research and public health, 17(4)

DOI 10.3390/ijerph17041191 PMID 32069859 PMC PMC7068519

Abstract

Dysmenorrhea often significantly reduces the quality of women's life and is still an important public health problem. Despite numerous studies, the pathomechanism of dysmenorrhea is not fully understood. Previous research indicates the complexity of biochemical reactions between the endocrine, vascular, and immune systems. Prostaglandins play a major role in the pathomechanism of dysmenorrhea. In contrast, cytokines and other proinflammatory factors in primary dysmenorrhea are less studied. In addition to the applied pharmacotherapy, more and more studies proving the effectiveness of non-pharmacological methods appear. Therefore, the present work contains a review of the latest research concerning factors involved in dysmenorrhea, as well as therapeutic options. In the literature search, authors used online databases, PubMed, and clinitrials.gov and browsed through individual gynecology, physiotherapy journals and books.

Topics

General Gynecology Pelvic Pain Chronic Pelvic Pain

General Gynecology › Pelvic Pain › Chronic Pelvic Pain

Zofia Barcikowska, Elżbieta Rajkowska-Labon, Magdalena Emilia Grzybowska, Rita Hansdorfer-Korzon, Katarzyna Zorena

Z Barcikowska, E Rajkowska-Labon, M Grzybowska, R Hansdorfer-Korzon, K Zorena

PMID 32069859 32069859 DOI 10.3390/ijerph17041191 10.3390/ijerph17041191 Barcikowska et al. 2020, Barcikowska 2020

Keywords

dysmenorrhea, inflammation markers, progesterone, treatment, women’s health

Inflammatory Markers in Dysmenorrhea and Therapeutic Options

Abstract

Topics

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Keywords