Subfertility and risk of spontaneous abortion

Gray RH; Wu LY

doi:10.2105/ajph.90.9.1452

Pregnancy · Early Pregnancy

Subfertility and risk of spontaneous abortion

Gray RH, Wu LY

Published September 13, 2000 American Journal of Public Health, 90(9), 1452-1454

DOI 10.2105/ajph.90.9.1452 PMID 10983206

Abstract

Objectives

The purpose of this study was to assess the association between subfertility and spontaneous abortion.

Methods

A total of 1572 women in New York and Vermont reported 3269 pregnancies between 1980 and 1990 and were able to provide an estimate of the waiting time to conception for 2967. Subfertility was defined as a delay of 1 year or more before a recognized conception was achieved. Rates of spontaneous abortion were determined among women with and without subfertility, and adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated via multiple logistic regression.

Results

Spontaneous abortion rates were 23.0% in pregnancies preceded by subfertility and 14.0% in pregnancies without impaired fertility (adjusted OR = 1.71, 95% CI = 1.26, 2.94). The attributable risk of spontaneous abortion associated with subfertility was 6.2%.

Conclusions

Subfertile women evidence an increased number of spontaneous abortions.

Topics

Pregnancy Early Pregnancy Miscarriage

Pregnancy › Early Pregnancy › Miscarriage

Ronald H Gray

Ron Gray, R Gray

PMID 10983206 10983206 DOI 10.2105/ajph.90.9.1452 10.2105/ajph.90.9.1452 Gray et al. 2000, Gray 2000

Keywords

Abortion, Spontaneous/epidemiology/etiology, Adult, Female, Humans, Infertility, Female/complications, Logistic Models, Multivariate Analysis, New York/epidemiology, Odds Ratio, Pregnancy, Recurrence, Retrospective Studies, Risk Factors, Smoking/adverse Effects, Time Factors, Vermont/epidemiology

Subfertility and risk of spontaneous abortion

Abstract

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