The "dysharmonic luteal phase" syndrome: endometrial progesterone receptor and estradiol dehydrogenase

Achille Gravanis; Jean-René Zorn; Gisèle Tanguy; Catherine Nessmann; Lise Cedard; Paul Robel

doi:10.1016/s0015-0282(16)48198-7

Reproductive Endocrinology Luteal Phase

The "dysharmonic luteal phase" syndrome: endometrial progesterone receptor and estradiol dehydrogenase

Gravanis A, Zorn JR, Tanguy G, Nessmann C, Cedard L, Robel P

Published November 1984 Fertility and sterility

DOI 10.1016/s0015-0282(16)48198-7 PMID 6208059

Abstract

The dysharmonic luteal phase (DLP) syndrome is defined by delayed endometrial maturation despite normal plasma progesterone (P) values. In ten patients with DLP the actual date of the endometrial biopsy, dated retrospectively, was 24.7 +/- 2.3 days, whereas the histologic date was 20.0 +/- 2.6 days. The concentration of cytosolic P receptor in DLP endometrium tended to be lower, whereas the concentration of nuclear receptor was significantly higher in DLP than in seven matched patients with normal luteal phases. Endometrial estradiol-dehydrogenase activities were identical in both groups. The DLP syndrome cannot be explained by a decreased sensitivity of the endometrium to P and is probably merely functional in nature.

Topics

Reproductive Endocrinology › Luteal Phase › Luteal Phase Deficiency · Menstrual Cycle › Cycle Disorders › Ovulatory Disturbances · Diagnostics › Endometrial Assessment › Luteal Phase Biopsy

Achille Gravanis, Jean-René Zorn, Gisèle Tanguy, Catherine Nessmann, Lise Cedard, Paul Robel

A Gravanis, J Zorn, G Tanguy, Cathy Nessmann, Kate Nessmann, C Nessmann, L Cedard, P Robel

PMID 6208059 6208059 DOI 10.1016/s0015-0282(16)48198-7 10.1016/s0015-0282(16)48198-7 Gravanis et al. 1984, Gravanis 1984

The "dysharmonic luteal phase" syndrome: endometrial progesterone receptor and estradiol dehydrogenase

Abstract

Topics

By this author

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