The effect of estrogen and gestagen on the mucus production of human endocervical cells: a histochemical study

Edith Gaton; Liliana Zejdel; Dinu Bernstein; Marek Glezerman; Bernard Czernobilsky; Vaclav Insler

doi:10.1016/s0015-0282(16)46638-0

Reproductive Endocrinology Ovarian Hormones

The effect of estrogen and gestagen on the mucus production of human endocervical cells: a histochemical study

Gaton E, Zejdel L, Bernstein D, Glezerman M, Czernobilsky B, Insler V

Published November 1982 Fertility and sterility

DOI 10.1016/s0015-0282(16)46638-0 PMID 6215266

Abstract

The effect of hormonal stimulation on the intracellular mucus production of the endocervical cells was histochemically and morphometrically investigated. Twenty-seven cervixes from patients who had received estrogen or gestagen prior to hysterectomy were examined. "Upper" versus "lower" cervix and "small" versus "large" crypts were compared in both groups of patients. The histochemical analysis of mucins within the cells was based mainly on the combined alcian blue/periodic acid Schiff (AB/PAS) techniques at various pH levels. A semiquantitative estimation using cell counts and statistical evaluations was done for each staining method. The results indicate that sex hormones influence the chemical composition of endocervical mucus production. In addition, the nature of the intracellular mucus varies with the cryptal size and location within the cervical canal.

Topics

Reproductive Endocrinology Ovarian Hormones Estrogen

Reproductive Endocrinology › Ovarian Hormones › Estrogen

Edith Gaton, Liliana Zejdel, Dinu Bernstein, Marek Glezerman, Bernard Czernobilsky, Vaclav Insler

E Gaton, L Zejdel, D Bernstein, M Glezerman, B Czernobilsky, V Insler

PMID 6215266 6215266 DOI 10.1016/s0015-0282(16)46638-0 10.1016/s0015-0282(16)46638-0 Gaton et al. 1982, Gaton 1982

The effect of estrogen and gestagen on the mucus production of human endocervical cells: a histochemical study

Abstract

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