Factor VII Deficiency
Factor VII deficiency is a rare inherited bleeding disorder in which the body makes too little of clotting factor VII. Factor VII starts the chain of steps that forms a clot.
Women with the condition can have heavy periods, bleeding between periods, bleeding after surgery, and bleeding after birth. A clotting disorder is a common cause of heavy flow in young women. In a review of 2,770 adolescents with heavy periods, clotting disorders accounted for about 19 percent of cases.1
Clotting studies also belong in a workup for recurrent pregnancy loss. Evidence tying factor VII deficiency itself to miscarriage is thin.
Cited in this entry
- Hall EM, Ravelo AE, Aronoff SC, Del Vecchio MT. Systematic review and meta-analysis of the etiology of heavy menstrual bleeding in 2,770 adolescent females. BMC women's health. 2024. https://pubmed.ncbi.nlm.nih.gov/38378571/
This content is for educational purposes only and does not constitute medical advice. Consult an RRM clinician or healthcare provider for guidance specific to your situation.
