Myo-Inositol
Myo-inositol is a natural compound, similar to a sugar, that helps the cells of the body respond to insulin. Inside cells, it acts as a second messenger, a molecule that relays a signal. It helps insulin move sugar into the cell.1 Many women with polyendocrine metabolic ovarian syndrome (PMOS), formerly polycystic ovary syndrome (PCOS), have insulin resistance. Their cells do not respond well to insulin. Myo-inositol may help those cells respond better.1
In women with PMOS / PCOS, researchers have tested the effect of myo-inositol on cycles, hormones, and ovulation. In one study, many women had more regular cycles. The balance of LH and FSH also improved. These two hormones from the brain guide the ovaries.1 In a placebo-controlled trial, more women ovulated, and their testosterone levels fell.2
Researchers have also studied myo-inositol for egg quality.3 The strongest evidence is for blood sugar and hormone results in PMOS / PCOS. Results on pregnancy rates are less consistent across studies. No single dose is agreed on.1
Cited in this entry
- The Effectiveness of Myo-Inositol in Women With Polycystic Ovary Syndrome. https://pmc.ncbi.nlm.nih.gov/articles/PMC10926319/
- Costantino D, Minozzi G, Minozzi E, Guaraldi C. Metabolic and hormonal effects of myo-inositol in women with polycystic ovary syndrome: a double-blind trial. European Review for Medical and Pharmacological Sciences. 2009. https://pubmed.ncbi.nlm.nih.gov/19499845/
- Effect of myo-inositol supplementation in mixed ovarian response. https://pmc.ncbi.nlm.nih.gov/articles/PMC11968372/
This content is for educational purposes only and does not constitute medical advice. Consult an RRM clinician or healthcare provider for guidance specific to your situation.
