Myo-Inositol

By RRM Academy Reviewed by Dr. Naomi Whittaker, MD, Board-Certified OBGYN, MIGS, NFPMC, FCI Updated May 7, 2026

A naturally occurring carbocyclic sugar that acts as an insulin sensitizer and secondary messenger in FSH signaling. Used as a supplement in PCOS management. Evidence shows myo-inositol improves ovarian function, oocyte maturity rates, fertilization rates, and metabolic parameters (LH, FSH, HOMA-IR) in women with PCOS. A 2025 meta-analysis found statistically significant improvement in MII oocyte rate and fertilization rate, though evidence for clinical pregnancy rate improvement remains less conclusive.⁴⁰⁴¹⁴²

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