PMID 3204228 3204228 DOI 10.1037//0021-843x.97.4.429 10.1037//0021-843x.97.4.429
Cite this article
Trunnell, E. P., Turner, C. W., & Keye, W. R. (1988). A comparison of the psychological and hormonal factors in women with and without premenstrual syndrome. Journal of Abnormal Psychology, 97(4), 429-436. https://doi.org/10.1037//0021-843x.97.4.429
Trunnell EP, Turner CW, Keye WR. A comparison of the psychological and hormonal factors in women with and without premenstrual syndrome. J Abnorm Psychol. 1988;97(4):429-436. doi:10.1037//0021-843x.97.4.429
Trunnell, Eric P., et al. "A comparison of the psychological and hormonal factors in women with and without premenstrual syndrome." Journal of Abnormal Psychology, vol. 97, no. 4, 1988, pp. 429-436.
A variety of hypotheses have been proposed to explain the premenstrual syndromes. These hypotheses serve as rationales for an equally diverse range of proposed treatments. To investigate these hypotheses, we obtained multiple blood samples across the menstrual cycle in women with well-characterized menstrually related mood disorder and in control subjects. No diagnosis-related differences were observed in the levels or patterns of secretion of progesterone, estradiol, follicle-stimulating hormone, luteinizing hormone, testosterone-estradiol-binding globulin, dehydroepiandrosterone sulfate, dihydrotestosterone, prolactin, or cortisol. Our data suggest that premenstrual syndrome does not represent a simple hormonal deficiency and that the cited rationales for several of the proposed treatments are of questionable merit.
Klump KL et al., 2013·Journal of abnormal psychology
Studies suggest that within-person changes in estrogen and progesterone predict changes in binge eating across the menstrual cycle. However, samples have been extremely small (maximum N = 9), and analyses have not examined the interactive effects of hormones that are critical for changes in food intake in animals. The aims of the current study were to examine ovarian hormone interactions in the prediction of within-subject changes in emotional eating in the largest sample of women to date (N = 196). Participants provided daily ratings of emotional eating and saliva samples for hormone measurement for 45 consecutive days. Results confirmed that changes in ovarian hormones predict changes in emotional eating across the menstrual cycle, with a significant estradiol × progesterone interaction. Emotional eating scores were highest during the midluteal phase, when progesterone peaks and estradiol demonstrates a secondary peak. Findings extend previous work by highlighting significant interactions between estrogen and progesterone that explain midluteal increases in emotional eating. Future work should explore mechanisms (e.g., gene-hormone interactions) that contribute to both within- and between-subjects differences in emotional eating.