Assisted Reproduction · Registries and Reporting

HFEA Fertility Trends and Figures 2012

Human Fertilisation and Embryology Authority

2014

RRM Academy Synopsis

In 2011, 25.4% of UK Fresh Own-Egg IVF Cycles Led to a Live Birth

The UK regulator's yearly report on licensed clinics found that 25.4% of fresh own-egg IVF cycles led to a live birth in 2011. It counted 62,155 IVF or ICSI cycles among 47,422 women in 2012. Multiple births kept falling as single embryo transfers became more common.

Key Findings

  • 77 UK clinics did IVF and 72 did donor insemination (DI) in 2012. 47,422 women had 62,155 IVF or ICSI cycles; 2,265 women had 4,452 DI cycles.
  • The 2011 live birth rate for fresh cycles with a woman's own eggs was 32.2% at 18-34, 13.4% at 40-42, and 0.8% at 45+. The all-ages rate was 25.4%.
  • The multiple birth rate for fresh cycles at ages 18-34 fell from 21.3% to 20.0%. Across all ages it fell from 19.8% to 18.8%.
  • Elective single embryo transfer (eSET) rose from 16.8% of cycles in 2011 to 22.2% in 2012. One blastocyst kept multiple pregnancy risk near the natural rate of 1.59%, versus 37.0% after two.
  • The share of UK babies conceived through IVF rose from 0.3% in 1992 to 2.2% in 2011.

Interpretation

The report is a national registry summary, distinct from a clinical trial. The HFEA collected outcomes from nearly every licensed IVF cycle in the UK: 2011 for live births, 2012 for cycle activity. The scale makes the age-based rates solid population figures. But small age groups, like women 43 and older, can swing more year to year because fewer cycles are counted there. The report also separates the pregnancy rate, confirmed by ultrasound, from the live birth rate, since not every pregnancy ends in a birth. It does not test why one method works better, and says little about people who did not have IVF.

RRM Context

The registry tracks outcomes for a treatment that bypasses the reproductive system instead of asking why conception was not happening on its own. The registry's own numbers show success stayed steeply tied to age even in a monitored clinical setting, from 32.2% down to under 1% per cycle. RRM asks a different question first: what is causing infertility, and can it be treated. A registry like this reads IVF's population results. It does not report on restorative, cause-based care as a separate path.

Abstract not indexed. Read at source

Topics

By this author

Related research

Assisted Reproduction › Registries and Reporting › National Registry Data
Human Fertilisation and Embryology Authority et al. 2014, Human Fertilisation and Embryology Authority 2014