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Assisted Reproduction · Registries and Reporting

HFEA Fertility Trends and Figures 2013

Human Fertilisation and Embryology Authority

2015 Read at source
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RRM Academy Synopsis

UK Fertility Registry Shows IVF Success Rates By Age

The UK fertility regulator counts every licensed clinic's IVF, ICSI, and donor cycles each year. This report covers 2012 and 2013. About one quarter of IVF cycles using a woman's own fresh eggs led to a live birth. Fewer of those pregnancies involved twins or triplets than in past years.

Key Findings

  • UK clinics ran 64,600 IVF or ICSI cycles for 49,636 women, plus 4,611 donor insemination cycles for 2,379 women, in 2013 alone.
  • For cycles started in 2012 using a woman's own fresh eggs, 25.8% led to a live birth, edging up from 25.4% the year before.
  • Success dropped fast with age for own-fresh-egg cycles: 41.8% of embryo transfers led to a confirmed pregnancy at 18 to 34, but only 7.0% at 45 and older.
  • Twin and triplet pregnancies became less common, sliding from about 1 in 4 pregnancies in 2008 to about 1 in 6 by 2013.
  • That shift matched a change in practice: transferring one embryo on purpose rose from 4.9% of transfers in 2008 to 26.8% by 2013.

Interpretation

This is a mandatory national count. The count is not a designed study. UK law requires every clinic to report each cycle, describing what happened. The law does not require clinics to say why. For cycles using a woman's own eggs, age tracked closely with the odds at every step, from pregnancy to live birth. Live birth figures come from cycles a year earlier than the pregnancy figures, so the two are not matched before-and-after. Where an age band held only a handful of cycles, especially past 45, one or two extra births can swing that year's percentage sharply. A single year's figure for an older group is a weaker guide than the same figure in a large group.

RRM Context

This registry counts success per single IVF try, the measure clinics use. Restorative reproductive medicine research more often follows a couple for months and counts how many became pregnant over that whole time. A rate per try and a rate over many months are not the same thing, so the two do not compare directly.

Our editorial summary of this paper, not the article's abstract.

Abstract not indexed. Read at source

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Assisted Reproduction › Registries and Reporting › National Registry Data
Human Fertilisation and Embryology Authority et al. 2015, Human Fertilisation and Embryology Authority 2015

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Human Fertilisation and Embryology Authority (2015). HFEA Fertility Trends and Figures 2013.

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