2015
Abstract not indexed. Read at source
Topics
HFEA fertility trends statistics UK 2013, UK assisted reproduction data IVF success rates, Human Fertilisation Embryology Authority annual report, national IVF registry outcomes United Kingdom, assisted reproductive technology population trends, in vitro fertilisation cycle numbers UK, fertility treatment access statistics England Wales, donor conception trends HFEA data, ART live birth rates national registry, infertility treatment epidemiology United Kingdom
Cite this article
Human Fertilisation and Embryology Authority (2015). HFEA Fertility Trends and Figures 2013.
Human Fertilisation and Embryology Authority. HFEA Fertility Trends and Figures 2013. 2015.
Human Fertilisation and Embryology Authority. HFEA Fertility Trends and Figures 2013. 2015.
Related articles
InfertilityIVF OutcomesBirth Weight and Gestational AgeSibling Studies
Neonatal characteristics of children conceived with in vitro fertilization or intrauterine insemination compared with sibling births from unassisted conceptions
Reeder MR et al., 2026·Fertil Steril
To examine birth outcomes between children conceived with in vitro fertilization (IVF) or intrauterine insemination (IUI) and sibling births from unassisted conceptions. Retrospective sibling cohort. Live born children conceived via IVF, with or without intracytoplasmic sperm injection, or IUI at the Utah Center for Reproductive Medicine, 1999-2018, and sibling births from unassisted conceptions (born 1985-2018). The main analysis included singleton births (460 IVF, 666 IUI, and 1,579 unassisted siblings). In vitro fertilization, with or without intracytoplasmic sperm injection, or IUI. Preterm birth, low birth weight, small for gestational age, large for gestational age (LGA), and major congenital anomalies. Compared with unassisted siblings, singleton children conceived via IVF had gestational ages shorter by nearly half a week (95% confidence interval [CI], -0.6 to -0.3), birth weights of 72.1 g lower (95% CI, -118.8 to -25.4), and higher proportions of preterm birth (IVF, 11.1%; IUI, 8.7%; unassisted siblings, 6.8%), LGA (IVF, 9.1%; IUI, 4.5%; unassisted siblings, 5.9%), and major congenital anomalies (IVF, 3.7%; IUI, 2.0%; unassisted siblings, 1.4%). Models adjusted for maternal age, infant sex, infant birth year, previous pregnancy, and birth order showed that children conceived via IVF were more likely to be preterm (adjusted risk ratio [aRR], 1.6; 95% CI, 1.2-2.2; absolute difference, 4.3%) and LGA (aRR, 1.8; 95% CI, 1.2-2.5; absolute difference, 3.2%). Children conceived via IVF had a higher risk of major congenital anomalies than unassisted siblings adjusted for maternal age, infant sex, and birth order (aRR, 1.9; 95% CI, 1.0-3.8; absolute difference, 2.3%). Children conceived via IUI had birth weights 55.8 g lower (95% CI, -95.6 to -15.9) than unassisted siblings. We observed an increased risk of preterm birth, low birth weight, LGA, and major congenital anomalies among singleton children conceived with IVF compared with that among unassisted siblings; however, absolute differences remain small. For children conceived via IUI, lower birth weights were observed. These results suggest that treatment-related factors in addition to underlying subfertility may contribute to adverse birth outcomes.
InfertilityIVF OutcomesNational StatisticsPopulation-Level Trends
Fertility Treatment 2018: Trends and Figures
Human Fertilisation and Embryology Authority, 2020
# Fertility treatment 2018: **UK statistics for IVF and DI treatment, storage, and donation** 30 June 2020 Fertility trends is our annual statistical release. The key findings are published on this page with a statistical appendix available for download. [**Download the underlying data set in .xlsx (151kb)**](https://www.hfea.gov.uk/media/3293/underlying-data-tables-fertility-trends-2018.xlsx "download the data as .xlsx"). [**Download a PDF version of this report (1.04mb)**](https://www.hfea.gov.uk/media/3158/fertility-treatment-2018-trends-and-figures.pdf "Fertility treatment 2018: trends and figures"). ## - [Main points](https://www.hfea.gov.uk/about-us/publications/research-and-data/fertility-treatment-2018-trends-and-figures/#mainpoints) - [Section 1. IVF birth rates have increased for patients under 43 years](https://www.hfea.gov.uk/about-us/publications/research-and-data/fertility-treatment-2018-trends-and-figures/#birthrates) - [Section 2. Birth rates were above 20% per embryo transferred on average in the first three cycles](https://www.hfea.gov.uk/about-us/publications/research-and-data/fertility-treatment-2018-trends-and-figures/#birthrates2) - [Section 3. Using donor eggs can result in high birth rates for older patients, but they are not widely used](https://www.hfea.gov.uk/about-us/publications/research-and-data/fertility-treatment-2018-trends-and-figures/#donoreggs) - [Section 4. The multiple birth rate decreased further to 8% in 2018](https://www.hfea.gov.uk/about-us/publications/research-and-data/fertility-treatment-2018-trends-and-figures/#multiplebirths) - [Section 5. Transferring more than one embryo could result in a multiple birth rate over 30%](https://www.hfea.gov.uk/about-us/publications/research-and-data/fertility-treatment-2018-trends-and-figures/#multiplebirths2) - [Section 6. Embryo and egg storage have increased as freezing becomes more common](https://www.hfea...
InfertilityIVF OutcomesICSI vs Conventional IVFFollicular Development
Comparison of fertilization, cleavage and pregnancy rates of oocytes from large and small follicles
Bergh C et al., 1998·Hum Reprod
Ovarian stimulation for in-vitro fertilization (IVF) causes development of several cohorts of follicles. At the time of oocyte collection, oocytes are thus retrieved from a wide range of follicles of different sizes and developmental stages. A relationship between size of follicles and pregnancy rates has earlier been demonstrated. The aim of the present study was to compare fertilization, cleavage and pregnancy rates between oocytes retrieved from large and small follicles in conventional IVF and intracytoplasmic sperm injection (ICSI). A total of 200 conventional IVF patients and 175 ICSI patients underwent oocyte retrieval where oocytes from both large and small follicles were collected. A follicle with a volume of > or = 2 ml, corresponding to a follicular diameter > or = 16 mm as determined by ultrasound, was regarded as a large follicle. Only one cycle from each patient was included. Fertilization and cleavage rates were calculated per patient for oocytes from large and small follicles. The mean fertilization and cleavage rates for conventional IVF and ICSI cycles were calculated. Comparison of pregnancy rates was performed for patients receiving embryos derived from oocytes of only large or only small follicles. For conventional IVF patients, fertilization rates were 71.4 and 58.1% (P < 0.01, Wilcoxon paired test) for oocytes of large and small follicles respectively. The corresponding cleavage rates were 95.4 and 93.9% respectively. The pregnancy rate for the two groups was 47% (60/127) and 15% (2/13) (P < 0.05, chi2 test). For ICSI patients the fertilization rate was 72.0 and 71.1% for oocytes of large and small follicles respectively. The corresponding cleavage rate was 93.0 and 91.1%. The pregnancy rate in the two groups was 41% (46/113) and 42% (5/12). The results show that oocytes from smaller follicles also yield fertilization and pregnancies, although in conventional IVF to a lesser extent than oocytes from larger follicles. For IVF cycles, a higher proportion of immature oocytes (which are normally not included in the ICSI procedure) in the group of oocytes from small follicles is most probably the explanation for the lower fertilization rate. The decrease in pregnancy rate with oocytes from small follicles in the IVF cycles was not observed in the ICSI cycles. The possibility of evaluating the degree of oocyte maturation prior to fertilization may be an advantage of the ICSI technique. This suggests that the disadvantages of oocytes from small follicles might be overcome by means of ICSI.
InfertilityIVF Statistics and TrendsFamily Formation DemographicsNHS Fertility Funding
Family Formations in Fertility Treatment 2022
Human Fertilisation and Embryology Authority, 2024
# Family formations in fertility treatment 2022 Preliminary UK family type statistics for IVF and DI treatment, storage, November 2024 [Download the underlying dataset as .xlsx](https://www.hfea.gov.uk/media/zpjlvhnd/family-formations-in-fertility-treatment-2022-underlying-dataset.xlsx "Download the underlying dataset for the ‘Family formations in fertility treatment 2022’ report") ## - [Main points](https://www.hfea.gov.uk/about-us/publications/research-and-data/family-formations-in-fertility-treatment-2022/#main-points) - [Introduction](https://www.hfea.gov.uk/about-us/publications/research-and-data/family-formations-in-fertility-treatment-2022/#introduction) - [Section 1: The proportion of female same-sex couples and single patients having fertility treatment has changed](https://www.hfea.gov.uk/about-us/publications/research-and-data/family-formations-in-fertility-treatment-2022/#section-1) - [Section 2: IVF birth rates highest among female same-sex couples](https://www.hfea.gov.uk/about-us/publications/research-and-data/family-formations-in-fertility-treatment-2022/#section-2) - [Section 3: Single patients are starting IVF younger than previous years](https://www.hfea.gov.uk/about-us/publications/research-and-data/family-formations-in-fertility-treatment-2022/#section-3) - [Section 4: Patient population changes between those storing eggs and thawing them](https://www.hfea.gov.uk/about-us/publications/research-and-data/family-formations-in-fertility-treatment-2022/#section-4) - [Section 5: Average IVF multiple birth rate decreased across all family types](https://www.hfea.gov.uk/about-us/publications/research-and-data/family-formations-in-fertility-treatment-2022/#section-5) - [Section 6: Female same-sex couples and single patients had the lowest levels of NHS funding](https://www.hfea.gov.uk/about-us/publications/research-and-data/family-formations-in-fertility-treatment-2022/#section-6) - [Section 7: Up to two-thirds o...