Assisted Reproduction Registries and Reporting

Rapport médical et scientifique 2023 - Assistance Médicale à la Procréation et Diagnostic Préimplantatoire (Agence de la biomédecine Medical and Scientific Report 2023: Assisted Reproduction and Preimplantation Genetic Diagnosis; RAMS AMP/DPI 2023)

Agence de la biomédecine

Agence de la biomédecine - Rapport médical et scientifique, 2024

RRM Academy Synopsis

France's 2023 National ART Report Counted 27,455 Babies Born

Out of 164,670 fertility treatment cycles in 2023, France's national report counted 27,455 babies born. More than one in four IVF and ICSI egg retrievals produced no usable embryo. That count covers own eggs and sperm and leaves out freeze-all cycles. Multiple pregnancies fell to 5.3% of deliveries from 8.3% in 2020, alongside more single-embryo transfers.

Key Findings

  • France's 164,670 assisted reproduction attempts in 2023 led to 87,324 embryo transfers, 31,048 confirmed pregnancies, 26,876 deliveries, and 27,455 live-born children, with vital status unknown for 995 more.
  • An adjusted estimate put ART births at 28,440 in 2023: 4% of all children born in France, or nearly 1 in 24, up from about 1 in 27 in 2022.
  • 12.4% of ART children in 2023 were conceived using donor eggs, sperm, or embryos, roughly 3,460 children, up from 6.6% in 2022.
  • In 2023, 27.6% of standard IVF and 27.2% of ICSI cycles ended with no transferable embryo after retrieval, up from 25.1% and 26.2% in 2022. Own eggs and sperm; freeze-all excluded.
  • Among ICSI cycles using the couple's own eggs and sperm in 2023, the delivery rate per egg retrieval fell from 26.6% under age 30 to 7.1% at ages 40 to 42.

Interpretation

This is a government report. France's health agency, the Agence de la biomédecine, collects yearly data that every licensed fertility clinic must submit by law. The agency counts what happened nationwide in 2023. The dataset does not test a hypothesis, so these numbers describe outcomes across the whole country. The report does not adjust for age, diagnosis, or how many attempts a couple already made. So it cannot explain why success rates differ between techniques or years. The 'no embryo to transfer' and multiple-birth figures come from named groups, such as standard IVF or ICSI.

RRM Context

This report shows how ART outcomes in France change with age and technique. More than a quarter of 2023 IVF and ICSI retrievals with own eggs and sperm, freeze-all cycles excluded, produced no transferable embryo. Success also fell sharply with age. RRM clinicians read numbers like these as a reason to find out why conception is not happening before turning to assisted reproduction. Bypassing the reproductive system does not fix an underlying cause.

Key figures

Treatment activity, 2023

Measure Value Source
Number of clinico-biological centers practicing in vitro fertilization, 2023 105 VOLUME D’ACTIVITE SELON LA TECHNIQUE
Median annual oocyte retrievals per center practicing in vitro fertilization, 2023 471 VOLUME D’ACTIVITE SELON LA TECHNIQUE
Positive extraction rate (presence of spermatozoa) in surgical sperm retrieval procedures, 2023 51.1% RECUEIL CHIRURGICAL DE SPERMATOZOÏDES EN VUE D'AMP

Pregnancy and delivery rates, 2023

Measure Value Source
Delivery rate per intrauterine insemination using the couple's own gametes, 2023 10.9% INSEMINATION INTRA-UTERINE
Singleton deliveries as a share of deliveries after intrauterine insemination using the couple's own gametes, 2023 91.9% INSEMINATION INTRA-UTERINE
Ultrasound-confirmed pregnancies after fresh embryo transfer, conventional in vitro fertilization excluding ICSI, 2022 to 2023 3,175 to 2,961 Tableau AMP13

Children born after assisted reproduction, 2023

Measure Value Source
Total children born from assisted reproduction performed in 2023 27,455 ENFANTS ISSUS D'UNE AMP

Frozen embryo transfer, 2023

Measure Value Source
Freeze-all of the entire embryo cohort as a share of oocyte retrievals in in vitro fertilization attempts, 2023 26.6% LES EMBRYONS CONSERVES

Donor treatment, 2023

Measure Value Source
Conventional in vitro fertilization (excluding ICSI) fertilizations among donor oocyte fertilizations, 2023 10 (0.7%) TENTATIVES AVEC DON D'OVOCYTES
Oocyte donation attempts as a share of attempts using third-party donor gametes, 2023 12.6% CHIFFRES CLES DE L’ACTIVITE 2023
Embryo donation (reception of donated embryos) attempts as a share of attempts using third-party donor gametes, 2023 1.2% CHIFFRES CLES DE L’ACTIVITE 2023
Average number of oocytes injected per attempt using donor oocytes, 2023 5.7 Tableau AMP43
Female couples or unmarried women as a share of intrauterine insemination cycles using donor sperm, 2023 80.4% INSEMINATION INTRA-UTERINE
Ratio of assisted reproduction requests using donor sperm to donors accepted in the year, 2023 16.7 DONNEURS ET COUPLES OU FEMMES NON MARIEES RECEVEURS
Ratio of assisted reproduction requests using donor sperm to donors accepted in the year, 2022 (for comparison) 14 DONNEURS ET COUPLES OU FEMMES NON MARIEES RECEVEURS
Ratio of assisted reproduction requests using donor sperm to donors accepted in the year, 2021 (for comparison) 7.7 DONNEURS ET COUPLES OU FEMMES NON MARIEES RECEVEURS

Preimplantation genetic diagnosis, 2023

Measure Value Source
Molecular genetics requests accepted among those examined for preimplantation genetic diagnosis, 2023 59.7% Tableau DPI7
Cytogenetics requests accepted among those examined for preimplantation genetic diagnosis, 2023 68.5% Tableau DPI7

Trends, 2022 to 2023

Measure Value Source
Increase in intrauterine inseminations using donor sperm, 2022 to 2023 127% INSEMINATION INTRA-UTERINE

Our summary of the report's published figures, each citing its table, figure or section. The full report is at the publisher's link.

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Related research

Assisted Reproduction › Registries and Reporting › National Registry Data · Ethics and Policy › Policy and Regulation › Professional Standards
Agence de la biomédecine et al. 2024, Agence de la biomédecine 2024