Therapeutics · Ovulation Agents

Successful treatment of polycystic ovary syndrome with spironolactone or bromocriptine

Blum I, Kaufman H, Marilus R, Rusecki Y, Chovers I

Published May 1981 Obstetrics and Gynecology, 57(5), 661-665

Abstract

Marked improvement in the severe hypertension (250/150 mmHg) and hirsutism of a patient suffering from polycystic ovary syndrome was quickly achieved by the use of spironolactone 200 mg per day. Substitution of spironolactone with bromocriptine induced further amelioration of these symptoms and renewal of ovulatory cycles. These drugs may afford another mode of therapy in patients with polycystic ovary syndrome.

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Related research

Therapeutics › Ovulation Agents › Dopamine Agonists · Reproductive Endocrinology › Ovarian Hormones › Androgens · Menstrual Cycle › Cycle Disorders › Ovulatory Disturbances
Blum et al. 1981, Blum 1981