Human Reproduction Open, 2020

Unexplained recurrent pregnancy loss and unexplained infertility: twins in disguise

Fox CW, Savaris RF, Jeong JW, Kim TH, Miller PB, Likes CE, Schammel DP, Young SL, Lessey BA

Author affiliations (2)
  • University of North Carolina at Chapel Hill ROR
  • University of South Carolina ROR
DOI10.1093/hropen/hoz021 PMID36694811
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Abstract

Endometrial BCL6 protein levels are significantly elevated in women with unexplained recurrent pregnancy loss and unexplained infertility compared with fertile controls, with 79% of subfertile women displaying elevated BCL6. Among those with abnormal BCL6 who underwent laparoscopy, most were found to have endometriosis, suggesting a continuum of progesterone resistance and inflammatory/endometriosis-related endometrial dysfunction.

Topics

PMID 36694811 36694811 DOI 10.1093/hropen/hoz021 10.1093/hropen/hoz021 Fox et al. 2020, Fox 2020

Cite this article

Fox, C. W., Savaris, R. F., Jeong, J. W., Kim, T. H., Miller, P. B., Likes, C. E., Schammel, D. P., Young, S. L., & Lessey, B. A. (2020). Unexplained recurrent pregnancy loss and unexplained infertility: twins in disguise. Human Reproduction Open. https://doi.org/10.1093/hropen/hoz021

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