What is the number of older Canadians needed to screen by measurement of bone  density to detect an undiagnosed case of osteoporosis? a population-based study  from CaMos

Anna M Sawka; Alexandra Papaioannou; Robert G Josse; Timothy M Murray; George Ioannidis; David A Hanley; Jerilynn C Prior; Lehana Thabane; E A Papadimitropoulos; Amiram Gafni; Laura Pickard; Tassos Anastassiades; Susan Kirkland; Jonathan D Adachi; CaMos Research Group

doi:10.1016/j.jocd.2006.07.004

Bone Health · Osteoporosis

What is the number of older Canadians needed to screen by measurement of bone density to detect an undiagnosed case of osteoporosis? a population-based study from CaMos

Sawka AM, Papaioannou A, Josse RG, Murray TM, Ioannidis G, Hanley DA, Prior JC, Thabane L, Papadimitropoulos EA, Gafni A, Pickard L, Anastassiades T, Kirkland S, Adachi JD, CaMos Research Group

Published November 14, 2006 Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry, 9(4), 413-418

DOI 10.1016/j.jocd.2006.07.004 PMID 17097526

Abstract

Routine bone mineral densitometry (BMD) screening has been recommended for women aged >or=65 yr (Osteoporosis Canada [OC], International Society for Clinical Densitometry [ISCD], Canadian and United States Task Forces on Preventative Healthcare, and National Osteoporosis Foundation) and for men >or=65 yr (OC) or >or=70 yr (ISCD). We estimated the number of older Canadians needed to screen (NNS) by BMD to detect an undiagnosed case of osteoporosis, using prospective, multicenter, population-based data from the Canadian Multicentre Osteoporosis Study (CaMos). We included participants aged >or=65 yr with baseline dual-energy X-ray absorptiometry (DXA) BMDs at the femoral neck and lumbar spine (L1-L4). Osteoporosis was defined by a T-score or=65 yr. The percentage prevalence and 95% confidence intervals were determined. In individuals aged >or=65 yr, the prevalence of osteoporosis was 25.6% in women (95% confidence interval, 24.0%, 27.3%) and 8.9% in men (7.3%, 10.8%). In 652 men aged >or=70 yr, the prevalence of osteoporosis was 11.3% (9.1%, 14.0%). Of the participants with BMD-defined osteoporosis, 76.6% of woman aged >or=65 yr (73.2%, 79.6%; 516 of 674 women), 93.4% of men aged >or=65 yr (86.4%, 96.9%; 85 of 91), and 93.2% of men >or=70 yr (84.9%, 97.0%; 68 of 73) were not aware of it. Thus, the minimum NNS by BMD testing to detect one previously undiagnosed case of osteoporosis in Canada is: 6 women aged >or=65 yr, 13 men aged >or=65 yr, and 10 men aged >or=70 yr.

Topics

Bone Health Osteoporosis Diagnosis and Treatment

Bone Health › Osteoporosis › Diagnosis and Treatment

Anna M Sawka, Alexandra Papaioannou, Robert G Josse, Timothy M Murray, George Ioannidis, David A Hanley, Jerilynn C Prior, Lehana Thabane, Amiram Gafni, Laura Pickard, Tassos Anastassiades, Susan Kirkland, Jonathan D Adachi, Emmanuel A Papadimitropoulos

A Sawka, Alex Papaioannou, A Papaioannou, Bob Josse, Rob Josse, Bobby Josse, R Josse, Tim Murray, T Murray, G Ioannidis, Dave Hanley, D Hanley, J Prior, L Thabane, A Gafni, L Pickard, T Anastassiades, Sue Kirkland, S Kirkland, Jon Adachi, J Adachi, E Papadimitropoulos

PMID 17097526 17097526 DOI 10.1016/j.jocd.2006.07.004 10.1016/j.jocd.2006.07.004 Sawka et al. 2006, Sawka 2006

What is the number of older Canadians needed to screen by measurement of bone density to detect an undiagnosed case of osteoporosis? a population-based study from CaMos

Abstract

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