Antioxidant Therapy

By RRM Academy Reviewed by Dr. Naomi Whittaker, MD, Board-Certified OBGYN, MIGS, NFPMC, FCI Updated May 7, 2026

The therapeutic use of antioxidant compounds to reduce oxidative stress in both male and female reproductive contexts. In males, antioxidants (vitamin C, E, CoQ10, zinc, selenium, L-carnitine, N-acetylcysteine) reduce sperm DNA fragmentation and improve sperm parameters. In females, antioxidants support oocyte quality, reduce endometriosis-related oxidative damage, and may support embryo development.¹²

Cited in this entry

The Role of Sperm DNA Fragmentation in the Evaluation of the Male Factor. SSMR. https://ssmr.org/patients/patient-resources/patient-education-forum/the-role-of-sperm-dna-fragmentation-in-the-evaluat.aspx
Sperm DNA Fragmentation: causes, evaluation and management in male infertility. PMC. https://pmc.ncbi.nlm.nih.gov/articles/PMC11152411/

This content is for educational purposes only and does not constitute medical advice. Consult an RRM clinician or healthcare provider for guidance specific to your situation.