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Amenorrhea following oral contraception
A prospective study was done on 326 nulliparous women who ceased oral contraception. Follow-up was obtained on 311. The mean age was 20.3 years (SD 2.5). Eighty-nine per cent began menstruating within...
Natural family planning
A personal series of 600 private patients using natural family planning techniques is presented. The total failure rate was 4.7 pregnancies per 100 woman-years. The advantages of this method over conv...
Identification of two related pentapeptides from the brain with potent opiate agonist activity
Enkephalin, a natural ligand for opiate receptors is composed of the pentapepides H-Tyr-Gly-Gly-Phe-Met-OH and H-Tyr-Gly-Gly-Phe-Leu-OH. The evidence is based on the determination of the amino acid se...
Obstacles to family planning practice in urban Morocco
Sixty in-depth interviews with mothers living in a urban slum of Morocco probed resistances to practicing modern methods of fertility control and began to shed light on some of the reasons family plan...
Hormone May Curb Premature Births
RETURN TO ISSUEPREVNewsNEXTHormone may curb premature birthsCite this: Chem. Eng. News 1975, 53, 41, 4–5Publication Date (Print):October 13, 1975Publication History Published online7 November 2010Publ...
Efficacy of 17alpha-hydroxyprogesterone caproate in the prevention of premature labor
We conducted a double-blind study to determine the efficacy of 17alpha-hydroxyprogesterone caproate in preventing premature delivery in 43 high-risk patients. Premature delivery did not occur in 18 pa...
Excretion of progesterone metabolites and estriol in faeces from pregnant women during ampicillin administration
Progesterone metabolites and estriol were determined in urine and faeces collected daily from three pregnant women (33–37 weeks) before and during ampicillin administration (2 g/day orally). Two of th...
Retrospective and prospective epidemiological studies of 1500 karyotyped spontaneous human abortions
Epidemiologic studies, retrospective and prospective, were done on 1500 abortions collected from 1966-1972. No secular or seasonal variations were observed. From the analysis of the relative frequenci...
Mechanism of action of narcotics in the production of menstrual dysfunction in women
The ability of morphine to block ovulation in animals prompted investigation of the frequency and mechanisms of menstrual abnormalities in women addicted to narcotic analgesics. Menstrual histories ob...
Personality patterns of couples practicing the temperature-rhythm method of birth control
Psychological data was obtained from 1009 couples located in 5 countries who were practicing the temperature-rhythm method of birth control. In the U.S., survey instruments were distributed to 160 cou...
Circulating estradiol, estrone and gonadotropin levels following the administration of orally active 17beta-estradiol in postmenopausal women
Ingestion of a single tablet containing 2 mg micronized 17beta-estradiol (E-2) produced marked increases in the serum concentrations of E-2 and estrone (E-1) in 9 postmenopausal women. The rise in cir...
Hormones in human pregnancy. IV. Plasma progesterone
The plasma concentration of progesterone (P) has been measured by radioimmunoassay in maternal peripheral vein (M.P.V.) at early pregnancy and in M.P.V. umbilical artery (U.A.) and umbilical vein (U.V...
Isolation and characterization of 5alpha-pregnane-3,20-dione and progesterone in pepipheral blood of pregnant women. measurement throughout pregnancy
5alpha-Pregnane-3,20-dione and progesterone were isolated from a pregnancy plasma pool and were identified by using a combination of chromatographic techniques and mass spectrometry. Antibodies to pro...
Evaluation of ovulation and corpus luteum function using measurements of plasma progesterone
To develop a practical yet statistically valid means of indicating ovulation and adequacy of corpus luteum function concentrations of plasma progesterone (P) were measured daily during the luteal phas...
Progesterone concentrations in the sera of patients with intact and aborted hydatidiform moles
Ovulatory failure in a normal population and in patients with breast cancer
The luteal phase plasma progesterone levels of 341 control patients were compared with those in 25 patients with early and 12 patients with advanced breast cancer. There was a significant increase of ...
Low-dosage clomiphene therapy in the treatment of infertility due to defective ovulation
Summary: The use of clomiphene in gradually increasing doses, in cases of infertility due to anovulation, oligo-ovulation and inadequate luteal phase, led to a high pregnancy rate, particularly in the...
Low-dosage clomiphene therapy in the treatment of infertility due to defective ovulation
Measurement of serum LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the inadequate luteal phase
The irregular menses experienced by obese and/or hirsute women were studied by daily measurement of serum LH, FSH, estradiol (E2) and progesterone (P). During 8 cycles of 24 to 157 days, each episode ...
Estrogen and progesterone in plasma in relation to premenstrual tension
Plasma concentration of estrogen and progesterone were measured during the last 6 days of the menstrual cycle in women with premenstrual tension, and compared with a group of healthy women. Those wome...
Effect of progesterone and 17-hydroxyprogesterone caproate on normal corpus luteum function
A group of infertility patients were evaluated by an endometrial biopsy, timed with a basal body temperature chart, serum luteinizing hormone radioimmunassay to pinpoint ovulation, and daily serum pro...
Significant fall in progesterone and rise in oestradiol levels in human peripheral plasma before onset of labour
Plasma progesterone levels in normal and abnormal pregnancies
Plasma progesterone levels were estimated by competitive protein binding in 815 samples from healthy pregnant women with uncomplicated pregnancies. This series includes 32 patients who were followed s...
Recollections of my life with progesterone
This paper gives in narrative style those phases of the corpus luteum story in which the author was an active participant. The first part deals with the exciting days at the University of Rochester wh...
Levels of prostaglandins in human endometrium during the normal menstrual cycle
The levels of prostaglandins in the human endometrium throughout the normal menstrual cycle were measured by bioassay. The identity of prostaglandin F2alpha and prostaglandin E2 in endometrial tissue ...
Water and electrolytes in human cervical mucus
The ovulation method of family planning
The ovulation method of family planning relies on self-recognition of physiological changes occuring around time of ovulation rather than a calendar to enable a couple to avoid sexual intercourse duri...
Cycle pattern and pregnancy rate following combined clomiphene-estrogen therapy
Oestriol and prevention of breast cancer
Findings of estriol protective action against chemical carcinogens used to induce breast cancer in laboratory animals.
The influence of fetal sex on the levels of plasma progesterone in the human fetus
Progesterone levels in the human fetoplacental unit at term were determined by a competitive protein binding method. Progesterone levels in the umbilical vein were always higher than in the umbilical ...
The prevention of postoperative pelvic adhesions following conservative operative treatment for human infertility. A final 3-year follow-up report
A combination of Decadreon (dexamethasone) and Phenergan (promethazine) was tested in this collaborative study of 240 infertility patients as a means of preventing postoperative adhesion formation aft...
Ovulation method of family planning
Hyperbradykininism: a new orthostatic syndrome
The Cervical Score: A Simple Semiquantative Method for Monitoring of the Menstrual Cycle
A trial of the ovulation method of family planning in Tonga
A composite picture of the menstrual cycle
Ten ovulating women were studied to assess the interrelationships of various systemic, hormonal, and reproductive tract changes during normal menstrual cycles. Samples of blood, 24 hour urine specimen...
The hypothalamus and reproduction
This article has been designed to review recent developments in the field of hypothalamic hormones involved in the control of reproductive functions. A brief resume of early physiologic and anatomic s...
Stein-Leventhal syndrome
Endocrine profiles in premenstrual tension
Summary: Studies on pituitary and ovarian function as assessed by the urinary output of total gonadotrophic activity, the three classical oestrogens, pregnanediol and, in some cases, testosterone and ...
The applicability of labor inhibition to the problem of prematurity
Outcome of pregnancy after induced ovulation. Follow-up of pregnancies and children born after clomiphene therapy
Eighty-six women reached at least 20 weeks' pregnancy in 96 instances, after ovulation induced by clomiphene citrate. Although 37 of the women had 44 previous pregnancies, there had been a high pregna...
The effect of personal factors on the use of the basal body temperature method of regulating births
Plasma estrone, estradiol, estriol, progesterone, and 17-hydroxyprogesterone in human pregnancy. I. Normal pregnancy
To describe normal relationships between the various plasma unconjugated estrogens and progesterone during the second half of human pregnancy, the plasma concentrations of progesterone, 17-hydroxyprog...
Single luteal phase serum progesterone assay as an indicator of ovulation
A study was undertaken to determine whether solitary progesterone as says performed on serum samples obtained in the midluteal phase would provide the clinician with a convenient indicator that ovulat...
The significance of the human corpus luteum in pregnancy maintenance. I. Preliminary studies
Following the total removal of luteal tissue, circulating plasma progesterone, intrauterine pressure, oxytocin response, and clinical progress in abortion were determined sequentially in 12 first-trim...
Symptoms and hormonal changes accompanying ovulation
Luteal Phase Defects: Diagnosis and Implications
Cervical Mucus in Human Reproduction: Present State of Knowledge
Prostaglandin-induced myometrial activity inhibited by progesterone
PROSTAGLANDINS (PGs) are being used increasingly as abortifacients although their precise mechanism of action is uncertain. One of the compounds frequently used is PGF2α, which has been shown to stimu...