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(Ed) Seminars in Reproductive
Evidence for the involvement of beta-endorphin in the human menstrual cycle
The possibility that beta-endorphin, an endogenous opiate, is involved in the regulation of the menstrual cycle was examined. Daily serum beta-endorphin levels, in conjunction with luteinizing hormone...
Luteinizing hormone-releasing hormone release during the rat estrous cycle and after ovariectomy, as estimated with push-pull cannulae
A push-pull perfusion (PPP) system was used to carry out the first examination of LHRH release from the mediobasal hypothalami (MBH) of conscious, freely moving rats during stages of the estrous (E) c...
Natural family planning
Frequently, when one mentions natural family planning methods, the response is doubt, bewilderment, ridicule, or scorn. Much of this is due to the fact that many people know only of the rhythm method,...
Clomiphene and dexamethasone in women unresponsive to clomiphene alone
Twelve oligomenorrhic women with polycystic ovary syndrome (PCO) in whom clomiphene (250 mg daily for 5 days) and 10,000 IU human chorionic gonadotropin had failed to induce ovulation were treated wit...
Premature ovulation after ovarian ultrasonography
Whereas follicle rupture never occurred before the 37th hour after an ovulatory stimulus (either the onset of the LH surge or hCG administration) in control patients, ovulation was observed at 26 to 3...
Endocrine "conditioning" with endurance training a preliminary review
The human individual responds as an entire organism to the effect of endurance training. Exercise physiologists have long documented cardiovascular, musculo-skeletal and metabolic effects of condition...
Natural family planning: an analysis of change in procreative intention
beta-Endorphin in hypophyseal portal blood: variations throughout the menstrual cycle
Concentrations of beta-endorphin were measured in the venous effluent of the hypothalamus (hypophyseal portal blood) at various phases of the menstrual cycle and after ovariectomy in rhesus and pigtai...
Menstrual cycle changes with marathon training: anovulation and short luteal phase
Fourteen normal women (self-selected from 180 women enrolled) in a marathon training clinic kept basal body temperature (BBT), mileage, and weight records for 48 cycles before the marathon. Entry crit...
Reversible luteal phase changes and infertility associated with marathon training
Terminology and core curricula in natural family planning
22 physician-providers who serve natural family planning (NFP) programs, mostly in the private sector, gathered to formulate a standard terminology for the field. The Billings and sympto-thermal metho...
Trials of the ovulation method of natural family planning
Pip: The concept of utilizing changes in cervical secretion offers a potentially simple method of natural family planning. A detailed international trial has been conducted to test the effectiveness o...
Preliminary experience with the use of human chorionic gonadotrophin therapy in women with repeated abortion
A preliminary study of 'screened' women with two consecutive miscarriages revealed an incidence of abortion in 47.4% in a subsequent pregnancy whilst hCG therapy in a similar group of women where bioc...
The association between endometriosis and spontaneous abortion. A retrospective clinical study
Two hundred sixty-three patients with a diagnosis of endometriosis or adenomyosis were studied in a retrospective fashion. The association between endometriosis resulted in a spontaneous abortion rate...
Tamoxifen in the treatment of infertility associated with luteal phase deficiency
A group of 17 patients with suspected luteal phase deficiency was treated with tamoxifen. Tamoxifen therapy was found to lengthen the luteal phase in all patients and resulted in pregnancy in 6 of 17 ...
The human menstrual cycle: plasma concentrations of prolactin, LH, FSH, oestradiol and progesterone in conceiving and non-conceiving women
Hormonal profiles were obtained throughout 26 conception cycles and 27 non-conception control cycles. The pregnancies followed treatment (clomiphene or bromocriptine) in 12 women but were spontaneous ...
Natural family planning methods
Wade et al.'s report, entitled "A randomized prospective study of the use-effectiveness of 2 methods of natural family planning," contains items worthy of emphasis. These includes the following: 1) le...
"Abortion myths and realities": who is misleading whom?
Thomas W. Hilgers, M.D., testifying to the Australian Royal Commission on Human Relationships in 1975, alleged that liberal abortions laws in the U.S. caused more deaths among women of childbearing ag...
Atherosclerosis and oral contraceptive use. Serum from oral contraceptive users stimulates growth of arterial smooth muscle cells
Pooled serum from women taking a combined estrogen-progestin oral contraceptive preparation caused significantly greater cell proliferation and incorporation of 3H-thymidine into DNA in both human art...
Clomiphene citrate therapy of infertile women with low luteal phase progesterone levels
Sixty-nine infertile women with a midluteal serum progesterone level of 4 to 14 ng/ml were treated with a graduated dosage schedule of clomiphene citrate until the progesterone level on day 21 was gre...
Correlation between estradiol and progesterone in cycles with luteal phase deficiency
Many studies have been published on luteal phase deficiency, and the emphasis in most of them is on progesterone deficiency. In this study 144 patients (455 cycles) with infertility were studied. The ...
Ovulation detection in the human
The importance of predicting human ovulation for either optimizing or avoiding conception has been considered from an endocrine, morphological and clinical view point. Of the biochemical markers in pe...
Abnormal ovarian cycles as diagnosed by ultrasound and serum estradiol levels
A significant portion of human infertility is presumably due to defective ovulation, including patients who fail to conceive despite medical induction of ovulation, those who fail despite repeated tim...
Delay in conception for former 'pill' users
Interview data from 3,214 married women having planned pregnancies and singleton deliveries who had no history of fertility treatment and who conceived more than two weeks after cessation of contracep...
Teratogenic effects of cyproterone acetate and medroxyprogesterone treatment during the pre- and postimplantation period of mouse embryos. I
Pregnant mice were treated with a single subcutaneous injection of either cyproterone acetate (CA) or medroxyprogesterone acetate (MPA). In the first experiment the animals received 5-900 mg/kg of the...
Natural family planning: a review
This review of natural family planning (NFP) focuses on the following: components of the fertile phase; sympto-thermal methods; the history and methodology of NFP (calendar rhythm, basal body temperat...
The outcome of pregnancy resulting from clomiphene-induced ovulation
The outcome of pregnancy was studied in all women conceiving after ovulation induction with clomiphene at the gynaecological endocrine clinics operating in 2 Tasmanian cities. In 156 pregnancies where...
Evaluation of the use of Proluton-Depot (hydroxyprogesterone hexanoate) in early pregnancy
This study evaluates the effect of treatment with Proluton-Depot (hydroxyprogesterone hexanoate) in early pregnancy, and the final outcome of pregnancy and fetal status. One hundred and fifty patients...
Comparison between tamoxifen and clomiphene for induction of ovulation
The effectiveness of tamoxifen and clomiphene in inducing ovulation was compared in 46 women with anovulatory infertility. All the women were given both the drugs in an alternate way. If one cycle was...
Natural family planning: ovulation method after Billings (author's transl)
During the last decade, the World Health Organization has paid increasing attention to some reliable methods of birth control based on periodic abstinence. There are 2 main methods of natural family p...
Clues from Research into Cross-Species Fertilization
Dialysis encephalopathy and osteomalacic bone disease: a case-controlled study
Nine patients on long-term hemodialysis with dialysis encephalopathy were studied, with sex matched control subjects for eight of the patients. Each patient with dialysis encephalopathy and control su...
Endocrine, structural, and functional changes in the uterus during premature labor
Rats which were subjected to ovariectomy on day 18 of pregnancy and were treated with 17 beta-estradiol underwent delivery prematurely at 0900 +/- 1.9 hours on the morning of day 18. All animals had i...
The Beginnings of Human Life
Reproductive performance of women with uterine anomalies. An evaluation of 182 cases
A total of 182 women with uterine anomalies were observed over a period of 18 years. In all, 126 women had 265 pregnancies, fetal survival rate was 66%, perinatal mortality 8% and premature labors occ...
Medvei VC: A History of Endocrinology
Ovulation method of natural family planning
Past practices of Natural Family Planning (NFP) have included such techniques as: 1) calendar rhythm in which a constant mathematical relationship was calculated between the day of ovulation and the b...
Deficient cellular immunity in endometriosis
Cell-mediated autoimmune responses were studied by means of in vivo and in vitro techniques in five rhesus monkeys with spontaneous endometriosis. The results were compared with similar data obtained ...
Natural family planning IV. The identification of postovulatory infertility
The estimated time of ovulation (ETO) was correlated with the day of defined postovulatory infertility in 66 hormonally normal menstrual cycles from 24 subjects for each of 15 different natural family...
Adolescent contraception
Both the medical profession and the general public are becoming more and more aware of the need for adolescent contraception and the devastating consequences of the lack of such care. It is the respon...
Fertility following bilateral ovarian wedge resection: a critical analysis of 90 consecutive cases of the polycystic ovary syndrome
Fertility following bilateral ovarian wedge resection (BOWR) was evaluated in a retrospective cohort study of 90 consecutive cases of the polycystic ovary syndrome. Post-BOWR follow-up was available f...
Sex hormone-binding globulin concentrations in women with severe premenstrual syndrome
Sex hormone binding globulin (SHBG) binding capacity was measured in 50 women with severe premenstrual syndrome and 50 age-matched controls. The binding capacity was significantly lower (P = 0.001) in...
Do natural methods for fertility regulation increase the risks of genetic errors?
Genetic errors of many kinds are connected with the reproductive processes and are favored by a nunber of largely uncontrollable, endogenous, and/or exogenous factors. For a long time human beings hav...
A prospective multicentre trial of the ovulation method of natural family planning. I. The teaching phase
The percentage of 869 women in five countries capable of being taught to recognize the periovulatory cervical mucus symptom of the fertile period was determined in a prospective multicentre trial of t...
Breast cancer incidence in women with a history of progesterone deficiency
In order to investigate the nature of the association of involuntarily delayed first birth and risk of breast cancer, 1083 white women who had been evaluated and treated for infertility from 1945-1965...
Natural family planning III. Intermenstrual symptoms and estimated time of ovulation
Several periovulatory symptoms sometimes used in natural family planning are correlated with the estimated time of ovulation in 23 subjects and 64 hormonally normal menstrual cycles. The data suggest ...
Possible involvement of endorphin withdrawal or imbalance in specific premenstrual syndromes and postpartum depression
Puerperal Psychosis. Phenomena and diagnosis
Fifty-eight psychoses beginning within two weeks of childbirth are compared with 52 episodes of nonpuerperal psychotic illness occurring in young women. A clinical approach based on the use of multipl...