Assisted Reproduction · Registries and Reporting

Q-IVF Annual Report 2018: Fertility Treatments in Sweden (Treatment Year 2016)

Q-IVF, National Quality Registry for Assisted Reproduction

Q-IVF, 2018

RRM Academy Synopsis

Sweden's National IVF Registry Tracks Birth Rates By Age

A national Swedish registry tracked every clinic's IVF cycles from 2016. About 2 out of 10 fresh IVF cycles with a couple's own eggs led to a baby, and the odds fell fast with age.

Key Findings

  • Putting back just one embryo instead of two became far more common: 69.6% of fresh embryo transfers in 2007, versus 82.2% by 2016, with a couple's own eggs.
  • The report ties years of more single-embryo transfers to a falling multiple-birth rate: 3.1% for fresh cycles in 2016, and twins made up 2.8% of all IVF births.
  • Counted per embryo transfer (one or two embryos put back), 31.2% of fresh attempts and 28.6% of frozen ones using a couple's own eggs resulted in a baby.
  • When couples used a donor egg, roughly 28% of fresh attempts ended in a baby; the donor's age mattered more than the recipient's.
  • A fresh IVF cycle begun by a woman under 30 ended in a baby 28% of the time; for a woman 42 or older, that dropped to 6%.

Interpretation

This comes from Sweden's IVF quality registry. The registry counted results; it did not run a controlled comparison. So no single birth-rate change can be pinned on one cause. Small clinics or small age groups give shakier numbers, a limit the source names when it flags uncertainty in the clinic charts. The source only tracks IVF, donor-gamete, and insemination cycles. The report says nothing about other paths to pregnancy.

RRM Context

Reports like this show IVF's own numbers, in plain terms. Most cycles using a couple's own eggs did not end in a baby, and age was the strongest single factor in the outcome. Restorative reproductive medicine asks a different question: why is this couple infertile, and can that cause be treated? A registry this size makes IVF's real, age-driven odds easy to see.

Key figures

Treatment activity, 2016

Measure Value Source
IVF clinics operating in Sweden, 2016 17 Introduction
Public IVF clinics operating, 2016 6 Introduction
Private IVF clinics operating, 2016 11 Introduction
Share of clinics reporting to the Q-IVF registry, 2016 100% Introduction
Assisted reproduction treatments started, all types, 2016 21,145 Table 2
Fresh IVF/ICSI cycles started, all gamete types, 2016 12,810 Table 2
Freeze cycles started, all gamete types, 2016 6,297 Table 2
Freeze cycles started with own gametes, national total, 2016 6295 Figure 1
Fresh cycles started with own gametes, public clinics, 2016 4691 Figure 1
Freeze cycles started with own gametes, public clinics, 2016 2778 Figure 1
Fresh cycles started with own gametes, private clinics, 2016 7483 Figure 1
Freeze cycles started with own gametes, private clinics, 2016 3517 Figure 1
Fresh IVF/ICSI cycles started with own gametes, excluding PGD, 2016 11,954 Table 1
Share of started treatments that were fresh IVF/ICSI cycles, 2016 60.6% Figure 2
Share of started treatments that were freeze cycles, 2016 29.8% Figure 2
Share of started treatments that were donor insemination (AID), 2016 6.9% Figure 2
Share of started treatments that were own-oocyte freezing, 2016 1.8% Figure 2

IVF births in Sweden, 2016

Measure Value Source
Children born through IVF and their share of all Swedish births, 2016 5,182 (4.3%) Introduction

Treatment outcomes, 2016 (fresh IVF/ICSI cycles, all gamete types)

Measure Value Source
Cycles reaching oocyte retrieval, fresh IVF/ICSI, 2016 11,851 Figure 4
Cycles reaching embryo transfer, fresh IVF/ICSI, 2016 9,754 Figure 4
Cycles achieving clinical pregnancy, fresh IVF/ICSI, 2016 3,374 Figure 4
Cycles resulting in delivery, fresh IVF/ICSI, 2016 2,809 Figure 4

IVF outcomes with own gametes, 2016

Measure Value Source
Clinical pregnancies, fresh cycles, own gametes, 2016 2142 Table 1
Clinical pregnancies, freeze cycles, own gametes, 2016 2149 Table 1
Spontaneous abortions before week 22, fresh cycles, own gametes, 2016 447 Table 1
Spontaneous abortions before week 22, freeze cycles, own gametes, 2016 288 Table 1
Deliveries, own gametes, total, 2016 4,469 Table 1
Deliveries, fresh cycles, own gametes, 2016 2,642 Table 1
Deliveries, freeze cycles, own gametes, 2016 1,827 Table 1
Live born children, own gametes, total, 2016 4,531 Table 1
Live born children, fresh cycles, own gametes, 2016 2,679 Table 1
Live born children, freeze cycles, own gametes, 2016 1,852 Table 1

Delivery rates, own gametes IVF, 2016

Measure Value Source
Delivery rate per embryo transfer, fresh IVF, own gametes, 2016 31.2% Figure 10
Delivery rate per embryo transfer, freeze cycles, own gametes, 2016 28.6% Figure 10
Delivery rate per started cycle, fresh IVF, own gametes, 2016 22% Figure 9
Delivery rate per embryo transfer after single embryo transfer (SET), fresh IVF, own gametes, all ages, 2016 30% Figure 11
Delivery rate per embryo transfer after double embryo transfer (DET), fresh IVF, own gametes, all ages, 2016 22% Figure 11

Embryo transfer practice, 2016

Measure Value Source
Embryo transfers at blastocyst stage (day 5-6), fresh IVF, 2016 74% Figures 8a-8b
Embryo transfers at blastocyst stage (day 5-6), freeze cycles, 2016 81% Figures 8a-8b

Complications, fresh IVF cycles started 2016

Measure Value Source
Complications reported, fresh IVF cycles, 2016 162 Table 3
Complication rate among fresh IVF cycles, 2016 1.3% Table 3

Multiple births, 2016

Measure Value Source
Twin delivery rate, overall IVF, 2016 2.8% Table 4
Triplet delivery rate, overall IVF, 2016 0.1% Table 4
Twin delivery rate, fresh IVF, own gametes, 2016 3.06% Table 4
Triplet delivery rate, fresh IVF, own gametes, 2016 0.08% Table 4
Twin delivery rate, freeze cycles, own gametes, 2016 2.54% Table 4
Triplet delivery rate, freeze cycles, own gametes, 2016 0.11% Table 4

Oocyte freezing and fertility preservation, 2016

Measure Value Source
Oocyte freezing cycles started, all reasons, 2016 397 Table 2
Oocyte freezing cycles performed, all reasons, 2016 389 Figure 23
Oocyte freezing cycles for oncological indications, 2016 102 Figure 23
Oocyte freezing cycles for non-medical reasons, 2016 287 Figure 23

Donor treatment, 2016

Measure Value Source
Donor insemination (AID) treatments performed, 2016 1,452 Figures 19-20
Delivery rate per AID insemination, 2016 16.8% Figures 19-20
AID treatments performed at public clinics, 2016 867 Figure 19
AID treatments performed at private clinics, 2016 585 Figure 19
IVF cycles with donated oocytes started, total, 2016 342 Figure 15
IVF cycles with donated oocytes started, fresh, 2016 189 Figure 15
IVF cycles with donated oocytes started, freeze, 2016 153 Figure 15
IVF cycles with donated sperm started, total, 2016 758 Figure 15
IVF cycles with donated sperm started, fresh, 2016 447 Figure 15
IVF cycles with donated sperm started, freeze, 2016 311 Figure 15
Chance of a delivery per fresh treatment, own eggs with donated sperm, 2016 roughly 35% Report text
Chance of a delivery per fresh oocyte-donation treatment, 2016 roughly 28% Report text

Trends, single embryo transfer rate 2007 to 2016

Measure Value Source
Single embryo transfer (SET) rate trend, fresh IVF, own gametes, 2007 to 2016 69.6% to 82.2% Figure 6a
Single embryo transfer (SET) rate trend, freeze cycles, own gametes, 2007 to 2016 76.7% to 97.5% Figure 7b

Registry scale and context

Measure Value Source
Cumulative assisted reproduction treatments registered in Q-IVF, as of 2016 almost 190,000 How we collect data

Our summary of the report's published figures, each citing its table, figure or section. The full report is at the publisher's link.

Topics

By this author

Related research

Assisted Reproduction › Registries and Reporting › National Registry Data
Q-IVF et al. 2018, Q-IVF 2018